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Upstream Bio (UPB) Cash from Operations: 2023-2024

Historic Cash from Operations for Upstream Bio (UPB) over the last 2 years, with Dec 2024 value amounting to -$59.2 million.

  • Upstream Bio's Cash from Operations fell 59.29% to -$22.2 million in Q3 2025 from the same period last year, while for Sep 2025 it was -$122.3 million, marking a year-over-year decrease of 119.61%. This contributed to the annual value of -$59.2 million for FY2024, which is 56.02% down from last year.
  • Per Upstream Bio's latest filing, its Cash from Operations stood at -$59.2 million for FY2024, which was down 56.02% from -$37.9 million recorded in FY2023.
  • Upstream Bio's Cash from Operations' 5-year high stood at -$37.9 million during FY2023, with a 5-year trough of -$59.2 million in FY2024.
  • Moreover, its 2-year median value for Cash from Operations was -$48.5 million (2023), whereas its average is -$48.5 million.
  • Data for Upstream Bio's Cash from Operations shows a maximum YoY crashed of 56.02% (in 2024) over the last 5 years.
  • Yearly analysis of 2 years shows Upstream Bio's Cash from Operations stood at -$37.9 million in 2023, then plummeted by 56.02% to -$59.2 million in 2024.