Upstream Bio (UPB) Income from Continuing Operations (2023 - 2026)

Upstream Bio's (UPB) quarterly Income from Continuing Operations came in at 61786000.0 in Q1 2026, down 77.23% year-on-year from 271290342.32 in Q1 2025, and up 69.83% quarter-over-quarter from 204790000.0 in Q4 2025.

Upstream Bio (UPB) Income from Continuing Operations (2023 - 2026) Analysis & Trends

Upstream Bio's Income from Continuing Operations history runs 4 years deep, the most recent figure standing at 61786000.0 for Q1 2026.

  • On a quarterly basis, Income from Continuing Operations fell 77.23% year-over-year to 61786000.0 in Q1 2026; TTM through Mar 2026 was 483992000.0, a 146.9% decrease from a year earlier, with the FY2025 full-year figure at 305705000.0, down 123.29% from the prior year.
  • Income from Continuing Operations improved to 61786000.0 in Q1 2026 per UPB's latest filing, from 204790000.0 in the prior quarter.
  • Across five years, Income from Continuing Operations topped out at 7859000.0 in Q3 2023 and bottomed at 204790000.0 in Q4 2025.
  • The 4-year median for Income from Continuing Operations is 52506000.0 (2023), against an average of 68676090.91.
  • Biggest YoY gain for Income from Continuing Operations was 76.19% in 2024; the steepest drop was 549.96% in 2024.
  • Year by year, Income from Continuing Operations stood at 52506000.0 in 2023, then sank by 76.19% to 92508000.0 in 2024, then tumbled by 121.38% to 204790000.0 in 2025, then surged by 69.83% to 61786000.0 in 2026.
  • Per Business Quant, the three latest UPB Income from Continuing Operations figures stand at 61786000.0 (Q1 2026), 204790000.0 (Q4 2025), and 133269000.0 (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Income (Continuing) (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -37.09 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 227.36 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.68 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 727.20 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -26.94 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 362.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -453.82 Mn
10 Upstream Bio 347.73 Mn 347.73 Mn -3.94 Mn -61.79 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -61.79 Mn
Dec 31, 2025 -204.79 Mn
Sep 30, 2025 -133.27 Mn
Jun 30, 2025 -84.15 Mn
Mar 31, 2025 -34.86 Mn
Dec 31, 2024 -92.51 Mn
Sep 30, 2024 -51.08 Mn
Jun 30, 2024 -17.57 Mn
Mar 31, 2024 -15.06 Mn
Dec 31, 2023 -52.51 Mn
Sep 30, 2023 -7.86 Mn