Upstream Bio (UPB) Income from Continuing Operations (2023 - 2026)

Upstream Bio's quarterly Income from Continuing Operations came in at 40561000.0 in Q1 2026, down 48.74% year-on-year from 79125722.15 in Q1 2025, and up 4.59% quarter-over-quarter from 42513000.0 in Q4 2025.

Upstream Bio has reported Income from Continuing Operations for 4 years, with the latest figure at 40561000.0 in Q1 2026.

  • For the quarter ending Q1 2026, Income from Continuing Operations fell 48.74% year-over-year to 40561000.0; the trailing twelve-month figure through Mar 2026 stood at 156719000.0 (down 97.97% YoY), and the FY2025 full-year result was 143428000.0, down 118.5% from the prior year.
  • Income from Continuing Operations for Q1 2026 stood at 40561000.0, up from 42513000.0 in the prior quarter.
  • The five-year high for Income from Continuing Operations was 7859000.0 in Q3 2023, with the low at 42513000.0 in Q4 2025.
  • Average Income from Continuing Operations over 4 years is 24572727.27, with a median of 21242000.0 recorded in 2024.
  • Year-over-year, Income from Continuing Operations sank 172.22% in 2025 and sank 48.74% in 2026.
  • Tracing UPB's Income from Continuing Operations over 4 years: stood at 12811000.0 in 2023, then slumped by 65.81% to 21242000.0 in 2024, then slumped by 100.14% to 42513000.0 in 2025, then increased by 4.59% to 40561000.0 in 2026.
  • The last three Income from Continuing Operations figures came in at 40561000.0 (Q1 2026), 42513000.0 (Q4 2025), and 33729000.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Income (Continuing) (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -2.99 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -8.40 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -14.46 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.03 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.40 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 727.20 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 205.99 Mn
10 Upstream Bio 454.22 Mn 454.22 Mn -3.94 Mn -40.56 Mn

Historic Data

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DateValue
Mar 31, 2026 -40.56 Mn
Dec 31, 2025 -42.51 Mn
Sep 30, 2025 -33.73 Mn
Jun 30, 2025 -39.92 Mn
Mar 31, 2025 -27.27 Mn
Dec 31, 2024 -21.24 Mn
Sep 30, 2024 -15.99 Mn
Jun 30, 2024 -14.66 Mn
Mar 31, 2024 -13.75 Mn
Dec 31, 2023 -12.81 Mn
Sep 30, 2023 -7.86 Mn