Upstream Bio (UPB) Consolidated Net Income (2023 - 2026)

Upstream Bio's Consolidated Net Income history runs 4 years deep, the most recent figure standing at -$40.6 million for Q1 2026.

• In Q1 2026, Consolidated Net Income fell 48.74% year-over-year to -$40.6 million; the TTM figure through Mar 2026 stood at -$156.7 million (down 97.97% YoY), while the FY2025 annual figure was -$143.4 million, down 118.5% from the prior year.
• Consolidated Net Income was -$40.6 million for Q1 2026 at Upstream Bio, up from -$42.5 million in the prior quarter.
• In the past five years, Consolidated Net Income ranged from a high of -$7.9 million in Q3 2023 to a low of -$42.5 million in Q4 2025.
• Historically, Consolidated Net Income has averaged -$24.6 million across 4 years, with a median of -$21.2 million in 2024.
• The sharpest annual moves came in 2025 and 2026: Consolidated Net Income sank 172.22% in 2025, then sank 48.74% in 2026.
• A 4-year view of Consolidated Net Income shows it stood at -$12.8 million in 2023, then tumbled by 65.81% to -$21.2 million in 2024, then tumbled by 100.14% to -$42.5 million in 2025, then grew by 4.59% to -$40.6 million in 2026.
• The last three Consolidated Net Income figures came in at -$40.6 million (Q1 2026), -$42.5 million (Q4 2025), and -$33.7 million (Q3 2025), per Business Quant data.