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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInvested CapitalMarket CapitalizationNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Sales

Upstream Bio (UPB) Return on Sales: 2024-2025

Historic Return on Sales for Upstream Bio (UPB) over the last 2 years, with Sep 2025 value amounting to -43.64%.

  • Upstream Bio's Return on Sales fell 1772.00% to -43.64% in Q3 2025 from the same period last year, while for Sep 2025 it was -43.64%, marking a year-over-year decrease of 1772.00%. This contributed to the annual value of -27.70% for FY2024, which is 1259.00% down from last year.
  • Per Upstream Bio's latest filing, its Return on Sales stood at -43.64% for Q3 2025, which was down 13.81% from -38.35% recorded in Q2 2025.
  • In the past 5 years, Upstream Bio's Return on Sales registered a high of -22.10% during Q2 2024, and its lowest value of -43.64% during Q3 2025.
  • Moreover, its 2-year median value for Return on Sales was -31.09% (2024), whereas its average is -32.03%.
  • Data for Upstream Bio's Return on Sales shows a maximum YoY tumbled of 1,772bps (in 2025) over the last 5 years.
  • Over the past 2 years, Upstream Bio's Return on Sales (Quarterly) stood at -27.70% in 2024, then plummeted by 1,772bps to -43.64% in 2025.
  • Its Return on Sales was -43.64% in Q3 2025, compared to -38.35% in Q2 2025 and -34.48% in Q1 2025.