Upstream Bio (UPB) Return on Sales (2023 - 2025)

Historic Return on Sales for Upstream Bio (UPB) over the last 3 years, with Q3 2025 value amounting to 49.38%.

  • Upstream Bio's Return on Sales fell 230400.0% to 49.38% in Q3 2025 from the same period last year, while for Sep 2025 it was 43.64%, marking a year-over-year decrease of 177200.0%. This contributed to the annual value of 27.7% for FY2024, which is 125900.0% down from last year.
  • As of Q3 2025, Upstream Bio's Return on Sales stood at 49.38%, which was down 230400.0% from 42.6% recorded in Q2 2025.
  • Over the past 5 years, Upstream Bio's Return on Sales peaked at 12.66% during Q3 2023, and registered a low of 49.38% during Q3 2025.
  • Over the past 3 years, Upstream Bio's median Return on Sales value was 28.75% (recorded in 2024), while the average stood at 32.5%.
  • Its Return on Sales has fluctuated over the past 5 years, first plummeted by -61800bps in 2024, then crashed by -267000bps in 2025.
  • Quarter analysis of 3 years shows Upstream Bio's Return on Sales stood at 28.47% in 2023, then dropped by -22bps to 34.65% in 2024, then tumbled by -43bps to 49.38% in 2025.
  • Its Return on Sales stands at 49.38% for Q3 2025, versus 42.6% for Q2 2025 and 48.18% for Q1 2025.