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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInvested CapitalMarket CapitalizationNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Sales

Upstream Bio (UPB) Return on Sales: 2024-2025

Historic Return on Sales for Upstream Bio (UPB) over the last 2 years, with Sep 2025 value amounting to -43.64%.

  • Upstream Bio's Return on Sales fell 1772.00% to -43.64% in Q3 2025 from the same period last year, while for Sep 2025 it was -43.64%, marking a year-over-year decrease of 1772.00%. This contributed to the annual value of -27.70% for FY2024, which is 1259.00% down from last year.
  • Latest data reveals that Upstream Bio reported Return on Sales of -43.64% as of Q3 2025, which was down 13.81% from -38.35% recorded in Q2 2025.
  • In the past 5 years, Upstream Bio's Return on Sales ranged from a high of -22.10% in Q2 2024 and a low of -43.64% during Q3 2025.
  • Its 2-year average for Return on Sales is -32.03%, with a median of -31.09% in 2024.
  • Data for Upstream Bio's Return on Sales shows a maximum YoY tumbled of 1,772bps (in 2025) over the last 5 years.
  • Upstream Bio's Return on Sales (Quarterly) stood at -27.70% in 2024, then tumbled by 1,772bps to -43.64% in 2025.
  • Its Return on Sales was -43.64% in Q3 2025, compared to -38.35% in Q2 2025 and -34.48% in Q1 2025.