Upstream Bio (UPB) Other Operating Expenses (2024 - 2026)

Upstream Bio's (UPB) quarterly Other Operating Expenses came in at -$1.1 million in Q1 2026, down 5.6% year-on-year from -$1.2 million in Q1 2025, and up 14.97% quarter-over-quarter from -$1.3 million in Q4 2025.

Upstream Bio (UPB) Other Operating Expenses (2024 - 2026) Analysis & Trends

Upstream Bio's Other Operating Expenses history runs 3 years deep, the most recent figure standing at -$1.1 million for Q1 2026.

  • On a quarterly basis, Other Operating Expenses fell 5.6% year-over-year to -$1.1 million in Q1 2026; TTM through Mar 2026 was -$4.6 million, a 77.37% decrease from a year earlier, with the FY2025 full-year figure at -$4.5 million, down 127.77% from the prior year.
  • Other Operating Expenses improved to -$1.1 million in Q1 2026 per UPB's latest filing, from -$1.3 million in the prior quarter.
  • Across five years, Other Operating Expenses topped out at -$334000.0 in Q2 2024 and bottomed at -$1.3 million in Q4 2025.
  • The 3-year median for Other Operating Expenses is -$891000.0 (2025), against an average of -$843666.7.
  • Across the five-year window, Other Operating Expenses plunged 273.95% in 2025 and retreated 5.6% in 2026, its largest moves.
  • Year by year, Other Operating Expenses stood at -$836000.0 in 2024, then slumped by 56.58% to -$1.3 million in 2025, then grew by 14.97% to -$1.1 million in 2026.
  • Per Business Quant, the three latest UPB Other Operating Expenses figures stand at -$1.1 million (Q1 2026), -$1.3 million (Q4 2025), and -$891000.0 (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn
7 Belite Bio 61.40 Bn 61.40 Bn -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn
9 Revolution Medicines 37.37 Bn 37.37 Bn -
10 Upstream Bio 343.65 Mn 343.65 Mn -3.94 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -1.11 Mn
Dec 31, 2025 -1.31 Mn
Sep 30, 2025 -891,000.00
Jun 30, 2025 -1.25 Mn
Mar 31, 2025 -1.05 Mn
Dec 31, 2024 -836,000.00
Sep 30, 2024 -348,000.00
Jun 30, 2024 -334,000.00
Mar 31, 2024 -459,000.00