Upstream Bio (UPB) Return on Capital Employed (2024 - 2026)

Upstream Bio's Return on Capital Employed history runs 3 years deep, the most recent figure standing at 53.36% for Q1 2026.

• In Q1 2026, Return on Capital Employed fell 3274.0% year-over-year to 53.36%; the TTM figure through Mar 2026 stood at 53.36% (down 3274.0% YoY), while the FY2025 annual figure was 39.66%, down 1273.0% from the prior year.
• Return on Capital Employed was 53.36% for Q1 2026 at Upstream Bio, down from 44.66% in the prior quarter.
• In the past five years, Return on Capital Employed ranged from a high of 20.63% in Q1 2025 to a low of 53.36% in Q1 2026.
• Historically, Return on Capital Employed has averaged 34.2% across 3 years, with a median of 32.06% in 2025.
• The sharpest annual moves came in 2025 and 2026: Return on Capital Employed slumped 2222 bps in 2025, then tumbled 3274 bps in 2026.
• A 3-year view of Return on Capital Employed shows it stood at 22.44% in 2024, then slumped by 99 bps to 44.66% in 2025, then declined by 19 bps to 53.36% in 2026.
• The last three Return on Capital Employed figures came in at 53.36% (Q1 2026), 44.66% (Q4 2025), and 35.67% (Q3 2025), per Business Quant data.