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Upstream Bio (UPB) Retained Earnings (2023 - 2025)

Upstream Bio has reported Retained Earnings over the past 3 years, most recently at -$334.2 million for Q4 2025.

  • Quarterly results put Retained Earnings at -$334.2 million for Q4 2025, down 75.19% from a year ago — trailing twelve months through Dec 2025 was -$334.2 million (down 75.19% YoY), and the annual figure for FY2025 was -$334.2 million, down 75.19%.
  • Retained Earnings for Q4 2025 was -$334.2 million at Upstream Bio, down from -$291.8 million in the prior quarter.
  • Over the last five years, Retained Earnings for UPB hit a ceiling of $368000.0 in Q1 2025 and a floor of -$334.2 million in Q4 2025.
  • Median Retained Earnings over the past 3 years was -$190.8 million (2024), compared with a mean of -$177.7 million.
  • Biggest five-year swings in Retained Earnings: plummeted 908576.19% in 2024 and later tumbled 72.09% in 2025.
  • Upstream Bio's Retained Earnings stood at $21000.0 in 2023, then plummeted by 908576.19% to -$190.8 million in 2024, then crashed by 75.19% to -$334.2 million in 2025.
  • The last three reported values for Retained Earnings were -$334.2 million (Q4 2025), -$291.8 million (Q3 2025), and -$258.0 million (Q2 2025) per Business Quant data.