Upstream Bio (UPB) Retained Earnings (2023 - 2026)
Upstream Bio's (UPB) quarterly Retained Earnings came in at -$374.8 million in Q1 2026, down 156.51% year-on-year from $663.2 million in Q1 2025, and down 70819.62% quarter-over-quarter from $530000.0 in Q4 2025.
Upstream Bio (UPB) Retained Earnings (2023 - 2026) Analysis & Trends
Upstream Bio's Retained Earnings history runs 4 years deep, the most recent figure standing at -$374.8 million for Q1 2026.
- On a quarterly basis, Retained Earnings fell 156.51% year-over-year to -$374.8 million in Q1 2026; TTM through Mar 2026 was -$374.8 million, a 156.51% decrease from a year earlier, with the FY2025 full-year figure at $530000.0, down 99.92% from the prior year.
- Retained Earnings retreated to -$374.8 million in Q1 2026 per UPB's latest filing, from $530000.0 in the prior quarter.
- Across five years, Retained Earnings topped out at $666.4 million in Q2 2025 and bottomed at -$374.8 million in Q1 2026.
- The 4-year median for Retained Earnings is $6.8 million (2023), against an average of $203.8 million.
- Across the five-year window, Retained Earnings surged 13594.11% in 2024 and sank 156.51% in 2026, its largest moves.
- Year by year, Retained Earnings stood at $4.8 million in 2023, then jumped by 13594.11% to $660.6 million in 2024, then sank by 99.92% to $530000.0 in 2025, then slumped by 70819.62% to -$374.8 million in 2026.
- Per Business Quant, the three latest UPB Retained Earnings figures stand at -$374.8 million (Q1 2026), $530000.0 (Q4 2025), and $493000.0 (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Retained Earnings (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -527.87 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | -27.89 Mn |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 12.91 Bn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | 115.82 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 14.59 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 11.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 1.41 Bn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -622,000.00 |
| 10 | Upstream Bio | 347.73 Mn | 347.73 Mn | -3.94 Mn | -374.81 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -374.81 Mn |
| Dec 31, 2025 | 530,000.00 |
| Sep 30, 2025 | 493,000.00 |
| Jun 30, 2025 | 666.45 Mn |
| Mar 31, 2025 | 663.24 Mn |
| Dec 31, 2024 | 660.60 Mn |
| Sep 30, 2024 | 8.87 Mn |
| Dec 31, 2023 | 4.82 Mn |