Upstream Bio (UPB) Shares Outstanding (2023 - 2026)

Upstream Bio (UPB) recorded quarterly Shares Outstanding of $54.4 million in Q1 2026, little changed quarter-over-quarter from $54.2 million in Q4 2025, and up 1.45% on a YoY basis from $53.6 million in Q1 2025.

Upstream Bio (UPB) Shares Outstanding (2023 - 2026) Analysis & Trends

Upstream Bio's Shares Outstanding history runs 4 years deep, the most recent figure standing at $54.4 million for Q1 2026.

  • In Q1 2026, Shares Outstanding rose 1.45% year-over-year to $54.4 million; the TTM figure through Mar 2026 stood at $54.4 million (up 1.45% YoY), while the FY2025 annual figure was $54.2 million, up 1.18% from the prior year.
  • Shares Outstanding was $54.4 million for Q1 2026 at Upstream Bio, roughly flat from $54.2 million in the prior quarter.
  • In the past five years, Shares Outstanding ranged from a high of $54.4 million in Q1 2026 to a low of $3.0 million in Q3 2023.
  • Historically, Shares Outstanding has averaged $30.8 million across 4 years, with a median of $53.6 million in 2024.
  • The sharpest annual moves came in 2024 and 2025: Shares Outstanding soared 1691.27% in 2024, then gained 1.18% in 2025.
  • A 4-year view of Shares Outstanding shows it stood at $3.0 million in 2023, then jumped by 1691.27% to $53.6 million in 2024, then grew by 1.18% to $54.2 million in 2025, then increased by 0.34% to $54.4 million in 2026.
  • The last three Shares Outstanding figures came in at $54.4 million (Q1 2026), $54.2 million (Q4 2025), and $54.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Shares (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 40.14 Bn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 91.57 Bn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -1.88
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 254.16 Mn
9 Abivax 91.96 Bn 91.96 Bn - -
10 Upstream Bio 339.03 Mn 339.03 Mn -3.94 Mn 54.42 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 54.42 Mn
Mar 31, 2026 54.42 Mn
Mar 31, 2026 54.42 Mn
Mar 31, 2026 54.42 Mn
Mar 31, 2026 54.42 Mn
Mar 31, 2026 54.42 Mn
Mar 31, 2026 54.42 Mn
Mar 31, 2026 54.42 Mn
Dec 31, 2025 54.24 Mn
Dec 31, 2025 54.24 Mn
Dec 31, 2025 54.24 Mn
Dec 31, 2025 54.24 Mn
Dec 31, 2025 54.24 Mn
Dec 31, 2025 54.24 Mn
Dec 31, 2025 54.24 Mn
Dec 31, 2025 54.24 Mn
Sep 30, 2025 54.00 Mn
Sep 30, 2025 54.00 Mn
Sep 30, 2025 54.00 Mn
Sep 30, 2025 54.00 Mn