Upstream Bio (UPB) EBT Margin: 2023-2025

Historic EBT Margin for Upstream Bio (UPB) over the last 2 years, with Sep 2025 value amounting to -4,938.36%.

  • Upstream Bio's EBT Margin fell 230426.00% to -4,938.36% in Q3 2025 from the same period last year, while for Sep 2025 it was -4,364.31%, marking a year-over-year decrease of 177210.00%. This contributed to the annual value of -2,769.66% for FY2024, which is 125920.00% down from last year.
  • Per Upstream Bio's latest filing, its EBT Margin stood at -4,938.36% for Q3 2025, which was down 15.92% from -4,259.98% recorded in Q2 2025.
  • In the past 5 years, Upstream Bio's EBT Margin ranged from a high of -1,265.54% in Q3 2023 and a low of -4,938.36% during Q3 2025.
  • Its 3-year average for EBT Margin is -3,250.13%, with a median of -2,875.10% in 2024.
  • Data for Upstream Bio's EBT Margin shows a maximum YoY tumbled of 267,005bps (in 2025) over the last 5 years.
  • Upstream Bio's EBT Margin (Quarterly) stood at -2,846.89% in 2023, then tumbled by 61,836bps to -3,465.25% in 2024, then crashed by 230,426bps to -4,938.36% in 2025.
  • Its EBT Margin was -4,938.36% in Q3 2025, compared to -4,259.98% in Q2 2025 and -4,818.02% in Q1 2025.