Upstream Bio (UPB) EBT Margin (2023 - 2025)

Upstream Bio has reported EBT Margin over the past 3 years, most recently at 6364.22% for Q4 2025.

  • Quarterly results put EBT Margin at 6364.22% for Q4 2025, down 289897.0% from a year ago — trailing twelve months through Dec 2025 was 5025.51% (down 225585.0% YoY), and the annual figure for FY2025 was 5025.51%, down 225585.0%.
  • EBT Margin for Q4 2025 was 6364.22% at Upstream Bio, down from 4938.36% in the prior quarter.
  • Over the last five years, EBT Margin for UPB hit a ceiling of 1265.54% in Q3 2023 and a floor of 6364.22% in Q4 2025.
  • Median EBT Margin over the past 3 years was 3170.18% (2024), compared with a mean of 3561.54%.
  • Biggest five-year swings in EBT Margin: crashed -61836bps in 2024 and later plummeted -289897bps in 2025.
  • Upstream Bio's EBT Margin stood at 2846.89% in 2023, then dropped by -22bps to 3465.25% in 2024, then tumbled by -84bps to 6364.22% in 2025.
  • The last three reported values for EBT Margin were 6364.22% (Q4 2025), 4938.36% (Q3 2025), and 4259.98% (Q2 2025) per Business Quant data.