Upstream Bio (UPB) EBT Margin (2023 - 2026)

Upstream Bio's EBT Margin history runs 4 years deep, the most recent figure standing at 3922.73% for Q1 2026.

• In Q1 2026, EBT Margin rose 89529.0% year-over-year to 3922.73%; the TTM figure through Mar 2026 stood at 4717.61% (down 126970.0% YoY), while the FY2025 annual figure was 5025.51%, down 225585.0% from the prior year.
• EBT Margin was 3922.73% for Q1 2026 at Upstream Bio, up from 6364.22% in the prior quarter.
• In the past five years, EBT Margin ranged from a high of 1265.54% in Q3 2023 to a low of 6364.22% in Q4 2025.
• Historically, EBT Margin has averaged 3594.38% across 4 years, with a median of 3465.25% in 2024.
• The sharpest annual moves came in 2025 and 2026: EBT Margin plunged 289897 bps in 2025, then surged 89529 bps in 2026.
• A 4-year view of EBT Margin shows it stood at 2846.89% in 2023, then slipped by 22 bps to 3465.25% in 2024, then plunged by 84 bps to 6364.22% in 2025, then surged by 38 bps to 3922.73% in 2026.
• The last three EBT Margin figures came in at 3922.73% (Q1 2026), 6364.22% (Q4 2025), and 4938.36% (Q3 2025), per Business Quant data.