Upstream Bio (UPB) EBT (2023 - 2026)
Upstream Bio (UPB) reported EBT of -$39.71 million for Q2 2026, compared with -$39.92 million a year earlier.
Powered by 
Analysis
Upstream Bio (UPB) EBT (2023 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Upstream Bio's EBT came in at -$156.51 million; for FY2025, it came in at -$143.43 million.
- By year, EBT came in at -$65.64 million in FY2024 and -$35.95 million in FY2023.
- Five-year quarterly EBT spans a low of -$42.51 million in Q4 2025 and a high of -$7.86 million in Q3 2023.
- Per Business Quant data, the three quarters before Q2 2026 came in at -$40.56 million (Q1 2026), -$42.51 million (Q4 2025) and -$33.73 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 6.75 Bn |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 4.28 Bn |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -683.00 Mn |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 4.27 Bn |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 2.80 Bn |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 2.77 Bn |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -10.25 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -653.00 Mn |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 1.39 Bn |
| 10 | Upstream Bio | 290.29 Mn | 290.29 Mn | -3.29 Mn | -39.71 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -39.71 Mn |
| Mar 31, 2026 | -40.56 Mn |
| Dec 31, 2025 | -42.51 Mn |
| Sep 30, 2025 | -33.73 Mn |
| Jun 30, 2025 | -39.92 Mn |
| Mar 31, 2025 | -27.27 Mn |
| Dec 31, 2024 | -21.24 Mn |
| Sep 30, 2024 | -15.99 Mn |
| Jun 30, 2024 | -14.66 Mn |
| Mar 31, 2024 | -13.75 Mn |
| Dec 31, 2023 | -12.81 Mn |
| Sep 30, 2023 | -7.86 Mn |
API Access
Upstream Bio EBT API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebt&ticker=UPB&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebt", "ticker": "UPB", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebt&ticker=UPB&period=max&api_key=YOUR_API_KEY");
const data = await res.json();