Upstream Bio (UPB) Other Gross PP&E Adjustments (2023 - 2026)

Upstream Bio's quarterly Other Gross PP&E Adjustments came in at -$1.4 million in Q1 2026, up 24.47% year-on-year from -$1.1 million in Q1 2025, and down 32.81% quarter-over-quarter from -$1.1 million in Q4 2025.

Upstream Bio has reported Other Gross PP&E Adjustments for 4 years, with the latest figure at -$1.4 million in Q1 2026.

  • For the quarter ending Q1 2026, Other Gross PP&E Adjustments rose 24.47% year-over-year to -$1.4 million; the trailing twelve-month figure through Mar 2026 stood at -$1.4 million (up 24.47% YoY), and the FY2025 full-year result was -$1.1 million, up 29.81% from the prior year.
  • Other Gross PP&E Adjustments for Q1 2026 stood at -$1.4 million, down from -$1.1 million in the prior quarter.
  • The five-year high for Other Gross PP&E Adjustments was -$692000.0 in Q4 2023, with the low at -$2.0 million in Q3 2024.
  • Average Other Gross PP&E Adjustments over 4 years is -$1.4 million, with a median of -$1.5 million recorded in 2024.
  • Year-over-year, Other Gross PP&E Adjustments slumped 121.53% in 2024 and soared 45.8% in 2025.
  • Tracing UPB's Other Gross PP&E Adjustments over 4 years: stood at -$692000.0 in 2023, then slumped by 121.53% to -$1.5 million in 2024, then climbed by 29.81% to -$1.1 million in 2025, then slumped by 32.81% to -$1.4 million in 2026.
  • The last three Other Gross PP&E Adjustments figures came in at -$1.4 million (Q1 2026), -$1.1 million (Q4 2025), and -$1.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Other Gross PP&E Adjustments (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -83,048.00
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -60,691.22
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -285.20 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -892,000.00
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn -1.69 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn -
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn -189.30 Mn
10 Upstream Bio 454.22 Mn 454.22 Mn -3.94 Mn -1.43 Mn

Historic Data

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DateValue
Mar 31, 2026 -1.43 Mn
Mar 31, 2026 -1.43 Mn
Dec 31, 2025 -1.08 Mn
Dec 31, 2025 -1.08 Mn
Sep 30, 2025 -1.07 Mn
Sep 30, 2025 -1.07 Mn
Jun 30, 2025 -1.92 Mn
Jun 30, 2025 -1.92 Mn
Mar 31, 2025 -1.89 Mn
Mar 31, 2025 -1.89 Mn
Dec 31, 2024 -1.53 Mn
Dec 31, 2024 -1.53 Mn
Sep 30, 2024 -1.98 Mn
Sep 30, 2024 -1.98 Mn
Dec 31, 2023 -692,000.00
Dec 31, 2023 -692,000.00