Upstream Bio UPB
NASDAQ UPB
$5.97 -0.11 (-1.89%)
As of: Sep 4, 2026 · 3:56 PM EDT

Upstream Bio (UPB) EPS (Basic) (2023 - 2026)

Upstream Bio (UPB) posted quarterly EPS (Basic) of -$1.14 for Q1 2026, down 123.59% year-over-year from $4.82 in Q1 2025, and down 44.23% quarter-over-quarter from -$0.79 in Q4 2025.

Analysis

Upstream Bio (UPB) EPS (Basic) (2023 - 2026) Analysis & Trends

Upstream Bio's EPS (Basic) history runs 4 years deep, the most recent figure standing at -$1.14 for Q1 2026.

  • In Q1 2026, EPS (Basic) fell 123.59% year-over-year to -$1.14; the TTM figure through Mar 2026 stood at -$3.28 (down 95.88% YoY), while the FY2025 annual figure was -$2.66, up 52.29% from the prior year.
  • EPS (Basic) for Q1 2026 stood at -$1.14, down from -$0.79 in the prior quarter.
  • The five-year high for EPS (Basic) was -$0.51 in Q1 2025, with the low at -$6.96 in Q3 2024.
  • The 4-year median for EPS (Basic) is -$1.59 (2024), against an average of -$2.79.
  • The sharpest annual moves came in 2024 and 2025: EPS (Basic) plunged 229.2% in 2024, then jumped 91.01% in 2025.
  • Upstream Bio's EPS (Basic) stood at -$5.07 in 2023, then surged by 68.61% to -$1.59 in 2024, then soared by 50.49% to -$0.79 in 2025, then sank by 44.23% to -$1.14 in 2026.
  • Business Quant data shows UPB's EPS (Basic) at -$1.14 in Q1 2026, -$0.79 in Q4 2025, and -$0.63 in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EPS (Basic) (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 4.34
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 12.62
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 7.70
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -1.96
5 Revolution Medicines 44.33 Bn 44.33 Bn - -3.06
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 2.12
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 1.23
8 Royalty Pharma 28.45 Bn 27.61 Bn - 0.18
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -0.06
10 Upstream Bio 327.95 Mn 327.95 Mn -3.29 Mn -0.73
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -0.73
Mar 31, 2026 -0.81
Dec 31, 2025 -0.79
Sep 30, 2025 -0.63
Jun 30, 2025 -0.74
Mar 31, 2025 -0.51
Dec 31, 2024 -1.59
Sep 30, 2024 -6.96
Jun 30, 2024 -6.50
Mar 31, 2024 -4.68
Dec 31, 2023 -5.07
Sep 30, 2023 -2.11