Upstream Bio (UPB) EPS (Basic) (2023 - 2026)
Upstream Bio (UPB) posted quarterly EPS (Basic) of -$1.14 for Q1 2026, down 123.59% year-over-year from $4.82 in Q1 2025, and down 44.23% quarter-over-quarter from -$0.79 in Q4 2025.
Analysis
Upstream Bio (UPB) EPS (Basic) (2023 - 2026) Analysis & Trends
Upstream Bio's EPS (Basic) history runs 4 years deep, the most recent figure standing at -$1.14 for Q1 2026.
- In Q1 2026, EPS (Basic) fell 123.59% year-over-year to -$1.14; the TTM figure through Mar 2026 stood at -$3.28 (down 95.88% YoY), while the FY2025 annual figure was -$2.66, up 52.29% from the prior year.
- EPS (Basic) for Q1 2026 stood at -$1.14, down from -$0.79 in the prior quarter.
- The five-year high for EPS (Basic) was -$0.51 in Q1 2025, with the low at -$6.96 in Q3 2024.
- The 4-year median for EPS (Basic) is -$1.59 (2024), against an average of -$2.79.
- The sharpest annual moves came in 2024 and 2025: EPS (Basic) plunged 229.2% in 2024, then jumped 91.01% in 2025.
- Upstream Bio's EPS (Basic) stood at -$5.07 in 2023, then surged by 68.61% to -$1.59 in 2024, then soared by 50.49% to -$0.79 in 2025, then sank by 44.23% to -$1.14 in 2026.
- Business Quant data shows UPB's EPS (Basic) at -$1.14 in Q1 2026, -$0.79 in Q4 2025, and -$0.63 in Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EPS (Basic) (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 4.34 |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 12.62 |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 7.70 |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -1.96 |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | -3.06 |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 2.12 |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 1.23 |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 0.18 |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -0.06 |
| 10 | Upstream Bio | 327.95 Mn | 327.95 Mn | -3.29 Mn | -0.73 |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -0.73 |
| Mar 31, 2026 | -0.81 |
| Dec 31, 2025 | -0.79 |
| Sep 30, 2025 | -0.63 |
| Jun 30, 2025 | -0.74 |
| Mar 31, 2025 | -0.51 |
| Dec 31, 2024 | -1.59 |
| Sep 30, 2024 | -6.96 |
| Jun 30, 2024 | -6.50 |
| Mar 31, 2024 | -4.68 |
| Dec 31, 2023 | -5.07 |
| Sep 30, 2023 | -2.11 |