Upstream Bio (UPB) EPS (Basic) (2023 - 2026)
Upstream Bio's (UPB) quarterly EPS (Basic) came in at -$1.14 in Q1 2026, down 123.59% year-on-year from $4.82 in Q1 2025, and down 44.23% quarter-over-quarter from -$0.79 in Q4 2025.
Upstream Bio (UPB) EPS (Basic) (2023 - 2026) Analysis & Trends
Upstream Bio's EPS (Basic) history runs 4 years deep, the most recent figure standing at -$1.14 for Q1 2026.
- On a quarterly basis, EPS (Basic) fell 123.59% year-over-year to -$1.14 in Q1 2026; TTM through Mar 2026 was -$3.28, a 95.88% decrease from a year earlier, with the FY2025 full-year figure at -$2.66, up 52.29% from the prior year.
- EPS (Basic) eased to -$1.14 in Q1 2026 per UPB's latest filing, from -$0.79 in the prior quarter.
- Across five years, EPS (Basic) topped out at -$0.51 in Q1 2025 and bottomed at -$6.96 in Q3 2024.
- The 4-year median for EPS (Basic) is -$1.59 (2024), against an average of -$2.79.
- Across the five-year window, EPS (Basic) sank 229.2% in 2024 and jumped 91.01% in 2025, its largest moves.
- Year by year, EPS (Basic) stood at -$5.07 in 2023, then soared by 68.61% to -$1.59 in 2024, then jumped by 50.49% to -$0.79 in 2025, then plunged by 44.23% to -$1.14 in 2026.
- Per Business Quant, the three latest UPB EPS (Basic) figures stand at -$1.14 (Q1 2026), -$0.79 (Q4 2025), and -$0.63 (Q3 2025).
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EPS (Basic) (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | 0.00 |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 0.00 |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 0.16 |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 4.06 |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 6.99 |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 0.00 |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 5.90 |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -2.29 |
| 10 | Upstream Bio | 343.65 Mn | 343.65 Mn | -3.94 Mn | -1.14 |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -1.14 |
| Dec 31, 2025 | -0.79 |
| Sep 30, 2025 | -0.63 |
| Jun 30, 2025 | -0.74 |
| Mar 31, 2025 | -0.51 |
| Dec 31, 2024 | -1.59 |
| Sep 30, 2024 | -6.96 |
| Jun 30, 2024 | -6.50 |
| Mar 31, 2024 | -4.68 |
| Dec 31, 2023 | -5.07 |
| Sep 30, 2023 | -2.11 |