Upstream Bio (UPB) EPS (Basic) (2023 - 2026)
Upstream Bio (UPB) posted quarterly EPS (Basic) of -$1.14 for Q1 2026, down 123.59% year-over-year from $4.82 in Q1 2025, and down 44.23% quarter-over-quarter from -$0.79 in Q4 2025.
Upstream Bio (UPB) EPS (Basic) (2023 - 2026) Analysis & Trends
Upstream Bio's EPS (Basic) history runs 4 years deep, the most recent figure standing at -$1.14 for Q1 2026.
- In Q1 2026, EPS (Basic) fell 123.59% year-over-year to -$1.14; the TTM figure through Mar 2026 stood at -$3.28 (down 95.88% YoY), while the FY2025 annual figure was -$2.66, up 52.29% from the prior year.
- EPS (Basic) for Q1 2026 stood at -$1.14, down from -$0.79 in the prior quarter.
- The five-year high for EPS (Basic) was -$0.51 in Q1 2025, with the low at -$6.96 in Q3 2024.
- The 4-year median for EPS (Basic) is -$1.59 (2024), against an average of -$2.79.
- The sharpest annual moves came in 2024 and 2025: EPS (Basic) plunged 229.2% in 2024, then jumped 91.01% in 2025.
- Upstream Bio's EPS (Basic) stood at -$5.07 in 2023, then surged by 68.61% to -$1.59 in 2024, then soared by 50.49% to -$0.79 in 2025, then sank by 44.23% to -$1.14 in 2026.
- Business Quant data shows UPB's EPS (Basic) at -$1.14 in Q1 2026, -$0.79 in Q4 2025, and -$0.63 in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EPS (Basic) (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 4.34 |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 12.62 |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 7.59 |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -3.06 |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 0.16 |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 0.00 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 0.18 |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 1.23 |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -0.06 |
| 10 | Upstream Bio | 387.23 Mn | 387.23 Mn | -3.29 Mn | -0.90 |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -0.90 |
| Mar 31, 2026 | -1.14 |
| Dec 31, 2025 | -0.79 |
| Sep 30, 2025 | -0.63 |
| Jun 30, 2025 | -0.74 |
| Mar 31, 2025 | -0.51 |
| Dec 31, 2024 | -1.59 |
| Sep 30, 2024 | -6.96 |
| Jun 30, 2024 | -6.50 |
| Mar 31, 2024 | -4.68 |
| Dec 31, 2023 | -5.07 |
| Sep 30, 2023 | -2.11 |