Upstream Bio (UPB) Assets (2023 - 2026)

Upstream Bio (UPB) recorded quarterly Assets of $318.1 million in Q1 2026, down 10.1% quarter-over-quarter from $353.8 million in Q4 2025, and down 30.28% on a YoY basis from $456.2 million in Q1 2025.

Upstream Bio (UPB) Assets (2023 - 2026) Analysis & Trends

Upstream Bio's Assets history runs 4 years deep, the most recent figure standing at $318.1 million for Q1 2026.

  • In Q1 2026, Assets fell 30.28% year-over-year to $318.1 million; the TTM figure through Mar 2026 stood at $318.1 million (down 30.28% YoY), while the FY2025 annual figure was $353.8 million, down 26.56% from the prior year.
  • Assets was $318.1 million for Q1 2026 at Upstream Bio, down from $353.8 million in the prior quarter.
  • In the past five years, Assets ranged from a high of $481.7 million in Q4 2024 to a low of $117.2 million in Q4 2023.
  • Historically, Assets has averaged $346.4 million across 4 years, with a median of $372.5 million in 2025.
  • The sharpest annual moves came in 2024 and 2026: Assets jumped 311.03% in 2024, then sank 30.28% in 2026.
  • A 4-year view of Assets shows it stood at $117.2 million in 2023, then jumped by 311.03% to $481.7 million in 2024, then decreased by 26.56% to $353.8 million in 2025, then declined by 10.1% to $318.1 million in 2026.
  • The last three Assets figures came in at $318.1 million (Q1 2026), $353.8 million (Q4 2025), and $391.2 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Assets (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 37.37 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 811.27 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 14.93 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 1.73 Bn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 23.64 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 33.89 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 12.81 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 26.48 Bn
9 Abivax 91.96 Bn 91.96 Bn - 640.56 Mn
10 Upstream Bio 339.03 Mn 339.03 Mn -3.94 Mn 318.05 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 318.05 Mn
Dec 31, 2025 353.77 Mn
Sep 30, 2025 391.20 Mn
Jun 30, 2025 420.52 Mn
Mar 31, 2025 456.17 Mn
Dec 31, 2024 481.72 Mn
Sep 30, 2024 232.70 Mn
Dec 31, 2023 117.20 Mn