Upstream Bio (UPB) Assets (2023 - 2026)

Upstream Bio (UPB) posted quarterly Assets of $318.1 million for Q1 2026, down 30.28% year-over-year from $456.2 million in Q1 2025, and down 10.1% quarter-over-quarter from $353.8 million in Q4 2025.

Upstream Bio (UPB) Assets (2023 - 2026) Analysis & Trends

Upstream Bio's Assets history runs 4 years deep, the most recent figure standing at $318.1 million for Q1 2026.

  • In Q1 2026, Assets fell 30.28% year-over-year to $318.1 million; the TTM figure through Mar 2026 stood at $318.1 million (down 30.28% YoY), while the FY2025 annual figure was $353.8 million, down 26.56% from the prior year.
  • Assets for Q1 2026 stood at $318.1 million, down from $353.8 million in the prior quarter.
  • The five-year high for Assets was $481.7 million in Q4 2024, with the low at $117.2 million in Q4 2023.
  • The 4-year median for Assets is $372.5 million (2025), against an average of $346.4 million.
  • The sharpest annual moves came in 2024 and 2026: Assets soared 311.03% in 2024, then plunged 30.28% in 2026.
  • Upstream Bio's Assets stood at $117.2 million in 2023, then soared by 311.03% to $481.7 million in 2024, then retreated by 26.56% to $353.8 million in 2025, then dropped by 10.1% to $318.1 million in 2026.
  • Business Quant data shows UPB's Assets at $318.1 million in Q1 2026, $353.8 million in Q4 2025, and $391.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Assets (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 27.42 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 41.73 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 10.03 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 4.32 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 9.18 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 15.59 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 19.82 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 5.56 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 2.10 Bn
10 Upstream Bio 387.23 Mn 387.23 Mn -3.29 Mn 281.17 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 281.17 Mn
Mar 31, 2026 318.05 Mn
Dec 31, 2025 353.77 Mn
Sep 30, 2025 391.20 Mn
Jun 30, 2025 420.52 Mn
Mar 31, 2025 456.17 Mn
Dec 31, 2024 481.72 Mn
Sep 30, 2024 232.70 Mn
Dec 31, 2023 117.20 Mn