Upstream Bio (UPB) Assets (2023 - 2026)

Upstream Bio's (UPB) quarterly Assets came in at $318.1 million in Q1 2026, down 30.28% year-on-year from $456.2 million in Q1 2025, and down 10.1% quarter-over-quarter from $353.8 million in Q4 2025.

Upstream Bio (UPB) Assets (2023 - 2026) Analysis & Trends

Upstream Bio's Assets history runs 4 years deep, the most recent figure standing at $318.1 million for Q1 2026.

  • On a quarterly basis, Assets fell 30.28% year-over-year to $318.1 million in Q1 2026; TTM through Mar 2026 was $318.1 million, a 30.28% decrease from a year earlier, with the FY2025 full-year figure at $353.8 million, down 26.56% from the prior year.
  • Assets slipped to $318.1 million in Q1 2026 per UPB's latest filing, from $353.8 million in the prior quarter.
  • Across five years, Assets topped out at $481.7 million in Q4 2024 and bottomed at $117.2 million in Q4 2023.
  • The 4-year median for Assets is $372.5 million (2025), against an average of $346.4 million.
  • Across the five-year window, Assets soared 311.03% in 2024 and sank 30.28% in 2026, its largest moves.
  • Year by year, Assets stood at $117.2 million in 2023, then jumped by 311.03% to $481.7 million in 2024, then decreased by 26.56% to $353.8 million in 2025, then declined by 10.1% to $318.1 million in 2026.
  • Per Business Quant, the three latest UPB Assets figures stand at $318.1 million (Q1 2026), $353.8 million (Q4 2025), and $391.2 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Assets (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - 311.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - 78.88 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 8.55 Bn
4 NuCana 279.75 Bn 279.75 Bn - 39.68 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 26.48 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 40.87 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 811.27 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 10.03 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 2.25 Bn
10 Upstream Bio 347.73 Mn 347.73 Mn -3.94 Mn 318.05 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 318.05 Mn
Dec 31, 2025 353.77 Mn
Sep 30, 2025 391.20 Mn
Jun 30, 2025 420.52 Mn
Mar 31, 2025 456.17 Mn
Dec 31, 2024 481.72 Mn
Sep 30, 2024 232.70 Mn
Dec 31, 2023 117.20 Mn