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Upstream Bio (UPB) Return on Equity: 2024-2025

Historic Return on Equity for Upstream Bio (UPB) over the last 2 years, with Sep 2025 value amounting to -0.31%.

  • Upstream Bio's Return on Equity fell 68.00% to -0.31% in Q3 2025 from the same period last year, while for Sep 2025 it was -0.31%, marking a year-over-year decrease of 68.00%. This contributed to the annual value of -0.38% for FY2024, which is N/A change from last year.
  • Upstream Bio's Return on Equity amounted to -0.31% in Q3 2025, which was down 26.95% from -0.24% recorded in Q2 2025.
  • Upstream Bio's 5-year Return on Equity high stood at 0.37% for Q3 2024, and its period low was -0.42% during Q4 2024.
  • For the 2-year period, Upstream Bio's Return on Equity averaged around -0.07%, with its median value being -0.21% (2025).
  • Data for Upstream Bio's Return on Equity shows a maximum YoY tumbled of 68bps (in 2025) over the last 5 years.
  • Over the past 2 years, Upstream Bio's Return on Equity (Quarterly) stood at -0.42% in 2024, then crashed by 68bps to -0.31% in 2025.
  • Its Return on Equity was -0.31% in Q3 2025, compared to -0.24% in Q2 2025 and -0.17% in Q1 2025.