Upstream Bio (UPB) Return on Equity (2024 - 2026)

Upstream Bio's quarterly Return on Equity came in at 0.0% in Q1 2026, little changed year-on-year from 0.0% in Q1 2025, and down 21.93% quarter-over-quarter from 0.0% in Q4 2025.

Upstream Bio has reported Return on Equity for 3 years, with the latest figure at 0.0% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Equity changed 0.0% year-over-year to 0.0%; the trailing twelve-month figure through Mar 2026 stood at 0.0% (changed 0.0% YoY), and the FY2025 full-year result was 0.0%, changed 0.0% from the prior year.
  • Return on Equity for Q1 2026 stood at 0.0%, down from 0.0% in the prior quarter.
  • The five-year high for Return on Equity was 0.0% in Q3 2024, with the low at 0.0% in Q1 2026.
  • Average Return on Equity over 3 years is 0.0%, with a median of 0.0% recorded in 2025.
  • Peak annual rise in Return on Equity reached 0 bps in 2025, while the deepest fall reached 1 bps in 2025.
  • Tracing UPB's Return on Equity over 3 years: stood at 0.0% in 2024, then climbed by 6 bps to 0.0% in 2025, then declined by 22 bps to 0.0% in 2026.
  • The last three Return on Equity figures came in at 0.0% (Q1 2026), 0.0% (Q4 2025), and 0.0% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROE (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -0.04%
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -0.01%
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 0.00%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 0.00%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 0.01%
10 Upstream Bio 454.22 Mn 454.22 Mn -3.94 Mn 0.00%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 0.00%
Dec 31, 2025 0.00%
Sep 30, 2025 0.00%
Jun 30, 2025 0.00%
Mar 31, 2025 0.00%
Dec 31, 2024 0.00%
Sep 30, 2024 0.00%
Jun 30, 2024 0.00%