Upstream Bio (UPB) Change in Acquisitions & Divestments (2023 - 2026)
Upstream Bio (UPB) posted quarterly Change in Acquisitions & Divestments of $56.8 million for Q1 2026, up 7.87% year-over-year from $52.7 million in Q1 2025, and down 41.59% quarter-over-quarter from $97.3 million in Q4 2025.
Analysis
Upstream Bio (UPB) Change in Acquisitions & Divestments (2023 - 2026) Analysis & Trends
Upstream Bio's Change in Acquisitions & Divestments history runs 4 years deep, the most recent figure standing at $56.8 million for Q1 2026.
- In Q1 2026, Change in Acquisitions & Divestments rose 7.87% year-over-year to $56.8 million; the TTM figure through Mar 2026 stood at $296.7 million (up 20.1% YoY), while the FY2025 annual figure was $292.6 million, up 26.3% from the prior year.
- Change in Acquisitions & Divestments for Q1 2026 stood at $56.8 million, down from $97.3 million in the prior quarter.
- The five-year high for Change in Acquisitions & Divestments was $97.3 million in Q4 2025, with the low at $29.6 million in Q4 2023.
- The 4-year median for Change in Acquisitions & Divestments is $63.4 million (2025), against an average of $61.1 million.
- The sharpest annual moves came in 2024 and 2025: Change in Acquisitions & Divestments surged 185.25% in 2024, then declined 3.23% in 2025.
- Upstream Bio's Change in Acquisitions & Divestments stood at $29.6 million in 2023, then soared by 185.25% to $84.3 million in 2024, then gained by 15.39% to $97.3 million in 2025, then plunged by 41.59% to $56.8 million in 2026.
- Business Quant data shows UPB's Change in Acquisitions & Divestments at $56.8 million in Q1 2026, $97.3 million in Q4 2025, and $72.7 million in Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn |
| 10 | Upstream Bio | 327.95 Mn | 327.95 Mn | -3.29 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 66.70 Mn |
| Mar 31, 2026 | 56.82 Mn |
| Dec 31, 2025 | 97.28 Mn |
| Sep 30, 2025 | 72.71 Mn |
| Jun 30, 2025 | 69.90 Mn |
| Mar 31, 2025 | 52.68 Mn |
| Dec 31, 2024 | 84.30 Mn |
| Sep 30, 2024 | 75.14 Mn |
| Jun 30, 2024 | 34.93 Mn |
| Mar 31, 2024 | 37.26 Mn |
| Dec 31, 2023 | 29.55 Mn |