Upstream Bio (UPB) Change in Acquisitions & Divestments (2023 - 2026)
Upstream Bio (UPB) recorded quarterly Change in Acquisitions & Divestments of $56.8 million in Q1 2026, down 41.59% quarter-over-quarter from $97.3 million in Q4 2025, and up 7.87% on a YoY basis from $52.7 million in Q1 2025.
Upstream Bio (UPB) Change in Acquisitions & Divestments (2023 - 2026) Analysis & Trends
Upstream Bio's Change in Acquisitions & Divestments history runs 4 years deep, the most recent figure standing at $56.8 million for Q1 2026.
- In Q1 2026, Change in Acquisitions & Divestments rose 7.87% year-over-year to $56.8 million; the TTM figure through Mar 2026 stood at $296.7 million (up 20.1% YoY), while the FY2025 annual figure was $292.6 million, up 26.3% from the prior year.
- Change in Acquisitions & Divestments was $56.8 million for Q1 2026 at Upstream Bio, down from $97.3 million in the prior quarter.
- In the past five years, Change in Acquisitions & Divestments ranged from a high of $97.3 million in Q4 2025 to a low of $29.6 million in Q4 2023.
- Historically, Change in Acquisitions & Divestments has averaged $61.1 million across 4 years, with a median of $63.4 million in 2025.
- The sharpest annual moves came in 2024 and 2025: Change in Acquisitions & Divestments soared 185.25% in 2024, then fell 3.23% in 2025.
- A 4-year view of Change in Acquisitions & Divestments shows it stood at $29.6 million in 2023, then jumped by 185.25% to $84.3 million in 2024, then advanced by 15.39% to $97.3 million in 2025, then sank by 41.59% to $56.8 million in 2026.
- The last three Change in Acquisitions & Divestments figures came in at $56.8 million (Q1 2026), $97.3 million (Q4 2025), and $72.7 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - |
| 10 | Upstream Bio | 339.03 Mn | 339.03 Mn | -3.94 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 56.82 Mn |
| Mar 31, 2026 | 56.82 Mn |
| Dec 31, 2025 | 97.28 Mn |
| Dec 31, 2025 | 97.28 Mn |
| Sep 30, 2025 | 72.71 Mn |
| Sep 30, 2025 | 72.71 Mn |
| Jun 30, 2025 | 69.90 Mn |
| Jun 30, 2025 | 69.90 Mn |
| Mar 31, 2025 | 52.68 Mn |
| Mar 31, 2025 | 52.68 Mn |
| Dec 31, 2024 | 84.30 Mn |
| Dec 31, 2024 | 84.30 Mn |
| Sep 30, 2024 | 75.14 Mn |
| Sep 30, 2024 | 75.14 Mn |
| Jun 30, 2024 | 34.93 Mn |
| Jun 30, 2024 | 34.93 Mn |
| Mar 31, 2024 | 37.26 Mn |
| Mar 31, 2024 | 37.26 Mn |
| Dec 31, 2023 | 29.55 Mn |
| Dec 31, 2023 | 29.55 Mn |