Upstream Bio (UPB) Change in Acquisitions & Divestments (2023 - 2026)
Upstream Bio's (UPB) quarterly Change in Acquisitions & Divestments came in at $56.8 million in Q1 2026, up 7.87% year-on-year from $52.7 million in Q1 2025, and down 41.59% quarter-over-quarter from $97.3 million in Q4 2025.
Upstream Bio (UPB) Change in Acquisitions & Divestments (2023 - 2026) Analysis & Trends
Upstream Bio's Change in Acquisitions & Divestments history runs 4 years deep, the most recent figure standing at $56.8 million for Q1 2026.
- On a quarterly basis, Change in Acquisitions & Divestments rose 7.87% year-over-year to $56.8 million in Q1 2026; TTM through Mar 2026 was $296.7 million, a 20.1% increase from a year earlier, with the FY2025 full-year figure at $292.6 million, up 26.3% from the prior year.
- Change in Acquisitions & Divestments slipped to $56.8 million in Q1 2026 per UPB's latest filing, from $97.3 million in the prior quarter.
- Across five years, Change in Acquisitions & Divestments topped out at $97.3 million in Q4 2025 and bottomed at $29.6 million in Q4 2023.
- The 4-year median for Change in Acquisitions & Divestments is $63.4 million (2025), against an average of $61.1 million.
- Across the five-year window, Change in Acquisitions & Divestments surged 185.25% in 2024 and decreased 3.23% in 2025, its largest moves.
- Year by year, Change in Acquisitions & Divestments stood at $29.6 million in 2023, then jumped by 185.25% to $84.3 million in 2024, then advanced by 15.39% to $97.3 million in 2025, then tumbled by 41.59% to $56.8 million in 2026.
- Per Business Quant, the three latest UPB Change in Acquisitions & Divestments figures stand at $56.8 million (Q1 2026), $97.3 million (Q4 2025), and $72.7 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,222.41 Bn | 67,222.13 Bn | - |
| 2 | Nanobiotix | 1,909.44 Bn | 1,909.38 Bn | - |
| 3 | Akari Therapeutics | 989.71 Bn | 989.71 Bn | - |
| 4 | BeOne Medicines | 471.12 Bn | 466.33 Bn | 1.35 Bn |
| 5 | Vertex Pharmaceuticals | 121.84 Bn | 114.59 Bn | 2.59 Bn |
| 6 | Regeneron Pharmaceuticals | 69.89 Bn | 61.14 Bn | 3.31 Bn |
| 7 | Belite Bio | 62.74 Bn | 62.74 Bn | - |
| 8 | Argenx Se | 55.83 Bn | 50.64 Bn | 1.41 Bn |
| 9 | Alnylam Pharmaceuticals | 37.34 Bn | 34.34 Bn | 959.66 Mn |
| 10 | Upstream Bio | 346.37 Mn | 346.37 Mn | -3.94 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 56.82 Mn |
| Mar 31, 2026 | 56.82 Mn |
| Dec 31, 2025 | 97.28 Mn |
| Dec 31, 2025 | 97.28 Mn |
| Sep 30, 2025 | 72.71 Mn |
| Sep 30, 2025 | 72.71 Mn |
| Jun 30, 2025 | 69.90 Mn |
| Jun 30, 2025 | 69.90 Mn |
| Mar 31, 2025 | 52.68 Mn |
| Mar 31, 2025 | 52.68 Mn |
| Dec 31, 2024 | 84.30 Mn |
| Dec 31, 2024 | 84.30 Mn |
| Sep 30, 2024 | 75.14 Mn |
| Sep 30, 2024 | 75.14 Mn |
| Jun 30, 2024 | 34.93 Mn |
| Jun 30, 2024 | 34.93 Mn |
| Mar 31, 2024 | 37.26 Mn |
| Mar 31, 2024 | 37.26 Mn |
| Dec 31, 2023 | 29.55 Mn |
| Dec 31, 2023 | 29.55 Mn |