Upstream Bio (UPB) Change in Acquisitions & Divestments (2023 - 2026)

Upstream Bio (UPB) recorded quarterly Change in Acquisitions & Divestments of $56.8 million in Q1 2026, down 41.59% quarter-over-quarter from $97.3 million in Q4 2025, and up 7.87% on a YoY basis from $52.7 million in Q1 2025.

Upstream Bio (UPB) Change in Acquisitions & Divestments (2023 - 2026) Analysis & Trends

Upstream Bio's Change in Acquisitions & Divestments history runs 4 years deep, the most recent figure standing at $56.8 million for Q1 2026.

  • In Q1 2026, Change in Acquisitions & Divestments rose 7.87% year-over-year to $56.8 million; the TTM figure through Mar 2026 stood at $296.7 million (up 20.1% YoY), while the FY2025 annual figure was $292.6 million, up 26.3% from the prior year.
  • Change in Acquisitions & Divestments was $56.8 million for Q1 2026 at Upstream Bio, down from $97.3 million in the prior quarter.
  • In the past five years, Change in Acquisitions & Divestments ranged from a high of $97.3 million in Q4 2025 to a low of $29.6 million in Q4 2023.
  • Historically, Change in Acquisitions & Divestments has averaged $61.1 million across 4 years, with a median of $63.4 million in 2025.
  • The sharpest annual moves came in 2024 and 2025: Change in Acquisitions & Divestments soared 185.25% in 2024, then fell 3.23% in 2025.
  • A 4-year view of Change in Acquisitions & Divestments shows it stood at $29.6 million in 2023, then jumped by 185.25% to $84.3 million in 2024, then advanced by 15.39% to $97.3 million in 2025, then sank by 41.59% to $56.8 million in 2026.
  • The last three Change in Acquisitions & Divestments figures came in at $56.8 million (Q1 2026), $97.3 million (Q4 2025), and $72.7 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn -
7 Psyence Biomedical 212.16 Bn 212.16 Bn -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn
9 Abivax 91.96 Bn 91.96 Bn -
10 Upstream Bio 339.03 Mn 339.03 Mn -3.94 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 56.82 Mn
Mar 31, 2026 56.82 Mn
Dec 31, 2025 97.28 Mn
Dec 31, 2025 97.28 Mn
Sep 30, 2025 72.71 Mn
Sep 30, 2025 72.71 Mn
Jun 30, 2025 69.90 Mn
Jun 30, 2025 69.90 Mn
Mar 31, 2025 52.68 Mn
Mar 31, 2025 52.68 Mn
Dec 31, 2024 84.30 Mn
Dec 31, 2024 84.30 Mn
Sep 30, 2024 75.14 Mn
Sep 30, 2024 75.14 Mn
Jun 30, 2024 34.93 Mn
Jun 30, 2024 34.93 Mn
Mar 31, 2024 37.26 Mn
Mar 31, 2024 37.26 Mn
Dec 31, 2023 29.55 Mn
Dec 31, 2023 29.55 Mn