Upstream Bio UPB
NASDAQ UPB
$6.01 -0.07 (-1.15%)
As of: Sep 4, 2026 · 3:59 PM EDT

Upstream Bio (UPB) Change in Acquisitions & Divestments (2023 - 2026)

Upstream Bio (UPB) posted quarterly Change in Acquisitions & Divestments of $56.8 million for Q1 2026, up 7.87% year-over-year from $52.7 million in Q1 2025, and down 41.59% quarter-over-quarter from $97.3 million in Q4 2025.

Analysis

Upstream Bio (UPB) Change in Acquisitions & Divestments (2023 - 2026) Analysis & Trends

Upstream Bio's Change in Acquisitions & Divestments history runs 4 years deep, the most recent figure standing at $56.8 million for Q1 2026.

  • In Q1 2026, Change in Acquisitions & Divestments rose 7.87% year-over-year to $56.8 million; the TTM figure through Mar 2026 stood at $296.7 million (up 20.1% YoY), while the FY2025 annual figure was $292.6 million, up 26.3% from the prior year.
  • Change in Acquisitions & Divestments for Q1 2026 stood at $56.8 million, down from $97.3 million in the prior quarter.
  • The five-year high for Change in Acquisitions & Divestments was $97.3 million in Q4 2025, with the low at $29.6 million in Q4 2023.
  • The 4-year median for Change in Acquisitions & Divestments is $63.4 million (2025), against an average of $61.1 million.
  • The sharpest annual moves came in 2024 and 2025: Change in Acquisitions & Divestments surged 185.25% in 2024, then declined 3.23% in 2025.
  • Upstream Bio's Change in Acquisitions & Divestments stood at $29.6 million in 2023, then soared by 185.25% to $84.3 million in 2024, then gained by 15.39% to $97.3 million in 2025, then plunged by 41.59% to $56.8 million in 2026.
  • Business Quant data shows UPB's Change in Acquisitions & Divestments at $56.8 million in Q1 2026, $97.3 million in Q4 2025, and $72.7 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn -
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn
10 Upstream Bio 327.95 Mn 327.95 Mn -3.29 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 66.70 Mn
Mar 31, 2026 56.82 Mn
Dec 31, 2025 97.28 Mn
Sep 30, 2025 72.71 Mn
Jun 30, 2025 69.90 Mn
Mar 31, 2025 52.68 Mn
Dec 31, 2024 84.30 Mn
Sep 30, 2024 75.14 Mn
Jun 30, 2024 34.93 Mn
Mar 31, 2024 37.26 Mn
Dec 31, 2023 29.55 Mn