Upstream Bio (UPB) Net Income towards Common Stockholders (2023 - 2026)
Upstream Bio (UPB) posted quarterly Net Income towards Common Stockholders of -$61.8 million for Q1 2026, down 126.57% year-over-year from $232.5 million in Q1 2025, and down 45.52% quarter-over-quarter from -$42.5 million in Q4 2025.
Analysis
Upstream Bio (UPB) Net Income towards Common Stockholders (2023 - 2026) Analysis & Trends
Upstream Bio's Net Income towards Common Stockholders history runs 4 years deep, the most recent figure standing at -$61.8 million for Q1 2026.
- In Q1 2026, Net Income towards Common Stockholders fell 126.57% year-over-year to -$61.8 million; the TTM figure through Mar 2026 stood at -$178.0 million (down 98.49% YoY), while the FY2025 annual figure was -$143.4 million, down 87.76% from the prior year.
- Net Income towards Common Stockholders for Q1 2026 stood at -$61.8 million, down from -$42.5 million in the prior quarter.
- The five-year high for Net Income towards Common Stockholders was -$6.3 million in Q3 2023, with the low at -$61.8 million in Q1 2026.
- The 4-year median for Net Income towards Common Stockholders is -$21.8 million (2024), against an average of -$27.5 million.
- Peak annual rise in Net Income towards Common Stockholders reached 45.42% in 2024, while the deepest fall reached 236.37% in 2024.
- Upstream Bio's Net Income towards Common Stockholders stood at -$15.0 million in 2023, then plunged by 45.42% to -$21.8 million in 2024, then plunged by 94.86% to -$42.5 million in 2025, then plunged by 45.52% to -$61.8 million in 2026.
- Business Quant data shows UPB's Net Income towards Common Stockholders at -$61.8 million in Q1 2026, -$42.5 million in Q4 2025, and -$33.7 million in Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Income (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 1.10 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 1.30 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 472.00 Mn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -782.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | -644.37 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 237.01 Mn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 164.49 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 81.49 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -13.27 Mn |
| 10 | Upstream Bio | 327.95 Mn | 327.95 Mn | -3.29 Mn | -39.71 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -39.71 Mn |
| Mar 31, 2026 | -44.05 Mn |
| Dec 31, 2025 | -42.46 Mn |
| Sep 30, 2025 | -33.75 Mn |
| Jun 30, 2025 | -39.97 Mn |
| Mar 31, 2025 | -27.27 Mn |
| Dec 31, 2024 | -21.79 Mn |
| Sep 30, 2024 | -21.03 Mn |
| Jun 30, 2024 | -19.56 Mn |
| Mar 31, 2024 | -14.01 Mn |
| Dec 31, 2023 | -14.98 Mn |
| Sep 30, 2023 | -6.25 Mn |