Upstream Bio UPB
NASDAQ UPB
$6.01 -0.07 (-1.15%)
As of: Sep 4, 2026 · 3:59 PM EDT

Upstream Bio (UPB) Net Income towards Common Stockholders (2023 - 2026)

Upstream Bio (UPB) posted quarterly Net Income towards Common Stockholders of -$61.8 million for Q1 2026, down 126.57% year-over-year from $232.5 million in Q1 2025, and down 45.52% quarter-over-quarter from -$42.5 million in Q4 2025.

Analysis

Upstream Bio (UPB) Net Income towards Common Stockholders (2023 - 2026) Analysis & Trends

Upstream Bio's Net Income towards Common Stockholders history runs 4 years deep, the most recent figure standing at -$61.8 million for Q1 2026.

  • In Q1 2026, Net Income towards Common Stockholders fell 126.57% year-over-year to -$61.8 million; the TTM figure through Mar 2026 stood at -$178.0 million (down 98.49% YoY), while the FY2025 annual figure was -$143.4 million, down 87.76% from the prior year.
  • Net Income towards Common Stockholders for Q1 2026 stood at -$61.8 million, down from -$42.5 million in the prior quarter.
  • The five-year high for Net Income towards Common Stockholders was -$6.3 million in Q3 2023, with the low at -$61.8 million in Q1 2026.
  • The 4-year median for Net Income towards Common Stockholders is -$21.8 million (2024), against an average of -$27.5 million.
  • Peak annual rise in Net Income towards Common Stockholders reached 45.42% in 2024, while the deepest fall reached 236.37% in 2024.
  • Upstream Bio's Net Income towards Common Stockholders stood at -$15.0 million in 2023, then plunged by 45.42% to -$21.8 million in 2024, then plunged by 94.86% to -$42.5 million in 2025, then plunged by 45.52% to -$61.8 million in 2026.
  • Business Quant data shows UPB's Net Income towards Common Stockholders at -$61.8 million in Q1 2026, -$42.5 million in Q4 2025, and -$33.7 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 472.00 Mn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -782.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -644.37 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 237.01 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 164.49 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 81.49 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -13.27 Mn
10 Upstream Bio 327.95 Mn 327.95 Mn -3.29 Mn -39.71 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -39.71 Mn
Mar 31, 2026 -44.05 Mn
Dec 31, 2025 -42.46 Mn
Sep 30, 2025 -33.75 Mn
Jun 30, 2025 -39.97 Mn
Mar 31, 2025 -27.27 Mn
Dec 31, 2024 -21.79 Mn
Sep 30, 2024 -21.03 Mn
Jun 30, 2024 -19.56 Mn
Mar 31, 2024 -14.01 Mn
Dec 31, 2023 -14.98 Mn
Sep 30, 2023 -6.25 Mn