Upstream Bio (UPB) Net Income towards Common Stockholders (2023 - 2026)
Upstream Bio's (UPB) quarterly Net Income towards Common Stockholders came in at -$61.8 million in Q1 2026, down 126.57% year-on-year from $232.5 million in Q1 2025, and down 45.52% quarter-over-quarter from -$42.5 million in Q4 2025.
Upstream Bio (UPB) Net Income towards Common Stockholders (2023 - 2026) Analysis & Trends
Upstream Bio's Net Income towards Common Stockholders history runs 4 years deep, the most recent figure standing at -$61.8 million for Q1 2026.
- On a quarterly basis, Net Income towards Common Stockholders fell 126.57% year-over-year to -$61.8 million in Q1 2026; TTM through Mar 2026 was -$178.0 million, a 98.49% decrease from a year earlier, with the FY2025 full-year figure at -$143.4 million, down 87.76% from the prior year.
- Net Income towards Common Stockholders retreated to -$61.8 million in Q1 2026 per UPB's latest filing, from -$42.5 million in the prior quarter.
- Across five years, Net Income towards Common Stockholders topped out at -$6.3 million in Q3 2023 and bottomed at -$61.8 million in Q1 2026.
- The 4-year median for Net Income towards Common Stockholders is -$21.8 million (2024), against an average of -$27.5 million.
- Biggest YoY gain for Net Income towards Common Stockholders was 45.42% in 2024; the steepest drop was 236.37% in 2024.
- Year by year, Net Income towards Common Stockholders stood at -$15.0 million in 2023, then tumbled by 45.42% to -$21.8 million in 2024, then tumbled by 94.86% to -$42.5 million in 2025, then tumbled by 45.52% to -$61.8 million in 2026.
- Per Business Quant, the three latest UPB Net Income towards Common Stockholders figures stand at -$61.8 million (Q1 2026), -$42.5 million (Q4 2025), and -$33.7 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Income (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 66,621.14 Bn | 66,620.85 Bn | - | -625.73 |
| 2 | Nanobiotix | 1,915.18 Bn | 1,915.11 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -14.46 Mn |
| 4 | BeOne Medicines | 471.27 Bn | 466.48 Bn | 1.35 Bn | 227.36 Mn |
| 5 | Vertex Pharmaceuticals | 121.81 Bn | 114.57 Bn | 2.59 Bn | 1.03 Bn |
| 6 | Regeneron Pharmaceuticals | 69.58 Bn | 60.82 Bn | 3.31 Bn | 727.20 Mn |
| 7 | Belite Bio | 62.72 Bn | 62.72 Bn | - | -0.68 |
| 8 | Argenx Se | 55.51 Bn | 50.33 Bn | 1.41 Bn | 472.00 Mn |
| 9 | Revolution Medicines | 37.35 Bn | 37.35 Bn | - | -453.82 Mn |
| 10 | Upstream Bio | 347.18 Mn | 347.18 Mn | -3.94 Mn | -61.79 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -61.79 Mn |
| Dec 31, 2025 | -42.46 Mn |
| Sep 30, 2025 | -33.75 Mn |
| Jun 30, 2025 | -39.97 Mn |
| Mar 31, 2025 | -27.27 Mn |
| Dec 31, 2024 | -21.79 Mn |
| Sep 30, 2024 | -21.03 Mn |
| Jun 30, 2024 | -19.56 Mn |
| Mar 31, 2024 | -14.01 Mn |
| Dec 31, 2023 | -14.98 Mn |
| Sep 30, 2023 | -6.25 Mn |