Upstream Bio (UPB) EBITDA (2023 - 2025)

Upstream Bio (UPB) has 2 years of EBITDA data on record, last reported at -$40.4 million in Q3 2025.

  • For Q3 2025, EBITDA fell 91.61% year-over-year to -$40.4 million; the TTM value through Sep 2025 reached -$155.8 million, changed N/A, while the annual FY2024 figure was -$84.3 million, 110.26% down from the prior year.
  • EBITDA reached -$40.4 million in Q3 2025 per UPB's latest filing, up from -$54.3 million in the prior quarter.
  • Across five years, EBITDA topped out at -$15.0 million in Q1 2024 and bottomed at -$54.3 million in Q2 2025.