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Upstream Bio (UPB) Net Income: 2023-2025

Historic Net Income for Upstream Bio (UPB) over the last 2 years, with Sep 2025 value amounting to -$33.7 million.

  • Upstream Bio's Net Income fell 110.95% to -$33.7 million in Q3 2025 from the same period last year, while for Sep 2025 it was -$122.2 million, marking a year-over-year decrease of 113.52%. This contributed to the annual value of -$65.6 million for FY2024, which is 82.59% down from last year.
  • Upstream Bio's Net Income amounted to -$33.7 million in Q3 2025, which was up 15.50% from -$39.9 million recorded in Q2 2025.
  • In the past 5 years, Upstream Bio's Net Income ranged from a high of -$7.9 million in Q3 2023 and a low of -$39.9 million during Q2 2025.
  • Moreover, its 3-year median value for Net Income was -$16.0 million (2024), whereas its average is -$20.8 million.
  • Data for Upstream Bio's Net Income shows a maximum YoY tumbled of 172.22% (in 2025) over the last 5 years.
  • Quarterly analysis of 3 years shows Upstream Bio's Net Income stood at -$12.8 million in 2023, then tumbled by 65.81% to -$21.2 million in 2024, then crashed by 110.95% to -$33.7 million in 2025.
  • Its Net Income was -$33.7 million in Q3 2025, compared to -$39.9 million in Q2 2025 and -$27.3 million in Q1 2025.