Upstream Bio (UPB) Net Income (2023 - 2026)
Upstream Bio's Net Income came in at -$39.71 million for Q2 2026, compared with -$39.92 million a year earlier.
Powered by 
Analysis
Upstream Bio (UPB) Net Income (2023 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Upstream Bio reported Net Income of -$156.51 million; for FY2025, it was -$143.43 million.
- Going back by year, Net Income was -$65.64 million in FY2024 and -$35.95 million in FY2023.
- The five-year range for quarterly Net Income is -$42.51 million (Q4 2025) to -$7.86 million (Q3 2023).
- Business Quant data shows UPB's Net Income at -$40.56 million (Q1 2026), -$42.51 million (Q4 2025) and -$33.73 million (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Income (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 5.53 Bn |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | 3.62 Bn |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | -1.34 Bn |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 3.26 Bn |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 2.51 Bn |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 2.38 Bn |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -10.50 Bn |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | -237.00 Mn |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 1.10 Bn |
| 10 | Upstream Bio | 288.64 Mn | 288.64 Mn | -3.29 Mn | -39.71 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -39.71 Mn |
| Mar 31, 2026 | -40.56 Mn |
| Dec 31, 2025 | -42.51 Mn |
| Sep 30, 2025 | -33.73 Mn |
| Jun 30, 2025 | -39.92 Mn |
| Mar 31, 2025 | -27.27 Mn |
| Dec 31, 2024 | -21.24 Mn |
| Sep 30, 2024 | -15.99 Mn |
| Jun 30, 2024 | -14.66 Mn |
| Mar 31, 2024 | -13.75 Mn |
| Dec 31, 2023 | -12.81 Mn |
| Sep 30, 2023 | -7.86 Mn |
API Access
Upstream Bio Net Income API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-income&ticker=UPB&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-income", "ticker": "UPB", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-income&ticker=UPB&period=max&api_key=YOUR_API_KEY");
const data = await res.json();