Balance Sheet
Cash Flow Statement
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Upstream Bio (UPB) Cash from Investing Activities (2023 - 2025)

Upstream Bio has reported Cash from Investing Activities over the past 3 years, most recently at $58.9 million for Q4 2025.

  • Quarterly results put Cash from Investing Activities at $58.9 million for Q4 2025, up 40.65% from a year ago — trailing twelve months through Dec 2025 was -$93.5 million (down 57.15% YoY), and the annual figure for FY2025 was -$93.5 million, down 57.15%.
  • Cash from Investing Activities for Q4 2025 was $58.9 million at Upstream Bio, up from $48.2 million in the prior quarter.
  • Over the last five years, Cash from Investing Activities for UPB hit a ceiling of $58.9 million in Q4 2025 and a floor of -$213.4 million in Q1 2025.
  • Median Cash from Investing Activities over the past 3 years was $12.8 million (2025), compared with a mean of -$17.6 million.
  • Peak annual rise in Cash from Investing Activities hit 3319.87% in 2025, while the deepest fall reached 1640.43% in 2025.
  • Upstream Bio's Cash from Investing Activities stood at -$5.2 million in 2023, then skyrocketed by 899.47% to $41.9 million in 2024, then soared by 40.65% to $58.9 million in 2025.
  • The last three reported values for Cash from Investing Activities were $58.9 million (Q4 2025), $48.2 million (Q3 2025), and $12.8 million (Q2 2025) per Business Quant data.