Upstream Bio (UPB) Interest & Investment Income (2023 - 2026)

Upstream Bio's (UPB) quarterly Interest & Investment Income came in at $3.1 million in Q1 2026, down 35.61% year-on-year from $4.7 million in Q1 2025, and down 16.42% quarter-over-quarter from $3.7 million in Q4 2025.

Upstream Bio (UPB) Interest & Investment Income (2023 - 2026) Analysis & Trends

Upstream Bio's Interest & Investment Income history runs 4 years deep, the most recent figure standing at $3.1 million for Q1 2026.

  • On a quarterly basis, Interest & Investment Income fell 35.61% year-over-year to $3.1 million in Q1 2026; TTM through Mar 2026 was $10.7 million, a 15.65% decrease from a year earlier, with the FY2025 full-year figure at $16.9 million, up 39.68% from the prior year.
  • Interest & Investment Income declined to $3.1 million in Q1 2026 per UPB's latest filing, from $3.7 million in the prior quarter.
  • Across five years, Interest & Investment Income topped out at $5.1 million in Q4 2024 and bottomed at -$110000.0 in Q2 2025.
  • The 4-year median for Interest & Investment Income is $2.9 million (2024), against an average of $2.4 million.
  • Biggest YoY gain for Interest & Investment Income was 11392.86% in 2025; the steepest drop was 223.53% in 2025.
  • Year by year, Interest & Investment Income stood at $1.5 million in 2023, then jumped by 234.17% to $5.1 million in 2024, then declined by 28.01% to $3.7 million in 2025, then fell by 16.42% to $3.1 million in 2026.
  • Per Business Quant, the three latest UPB Interest & Investment Income figures stand at $3.1 million (Q1 2026), $3.7 million (Q4 2025), and $4.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Int & Inv Inc (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 27.66 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 114.80 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn -65.80 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 44.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 19.51 Mn
10 Upstream Bio 343.65 Mn 343.65 Mn -3.94 Mn 3.05 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 3.05 Mn
Dec 31, 2025 3.65 Mn
Sep 30, 2025 4.11 Mn
Jun 30, 2025 -110,000.00
Mar 31, 2025 4.74 Mn
Dec 31, 2024 5.08 Mn
Sep 30, 2024 2.90 Mn
Jun 30, 2024 -34,000.00
Mar 31, 2024 -42,000.00
Dec 31, 2023 1.52 Mn
Sep 30, 2023 1.53 Mn