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Upstream Bio (UPB) Gross Profit: 2023-2025

Historic Gross Profit for Upstream Bio (UPB) over the last 2 years, with Sep 2025 value amounting to -$1.9 million.

  • Upstream Bio's Gross Profit fell 18.26% to -$1.9 million in Q3 2025 from the same period last year, while for Sep 2025 it was -$14.6 million, marking a year-over-year decrease of 741.40%. This contributed to the annual value of -$4.2 million for FY2024, which is 323.97% down from last year.
  • Latest data reveals that Upstream Bio reported Gross Profit of -$1.9 million as of Q3 2025, which was up 79.49% from -$9.1 million recorded in Q2 2025.
  • In the past 5 years, Upstream Bio's Gross Profit registered a high of $621,000 during Q3 2023, and its lowest value of -$9.1 million during Q2 2025.
  • Over the past 3 years, Upstream Bio's median Gross Profit value was -$1.6 million (recorded in 2025), while the average stood at -$1.8 million.
  • Data for Upstream Bio's Gross Profit shows a maximum YoY crashed of 900.33% (in 2025) over the last 5 years.
  • Over the past 3 years, Upstream Bio's Gross Profit (Quarterly) stood at $450,000 in 2023, then slumped by 577.11% to -$2.1 million in 2024, then dropped by 18.26% to -$1.9 million in 2025.
  • Its Gross Profit was -$1.9 million in Q3 2025, compared to -$9.1 million in Q2 2025 and -$1.6 million in Q1 2025.