Balance Sheet
Cash Flow Statement
Daily Values
Growth Metrics
Income Statement
Consolidated Net IncomeCost of RevenueEBITEBITDAEBTEPS (Basic)EPS (Weighted Average and Diluted)Gross ProfitIncome from Continuing OperationsIncome towards Parent CompanyInterest & Investment IncomeNet Income towards Common StockholdersNon Operating IncomeOperating ExpensesOperating IncomeOther Operating ExpensesPreferred Dividend PaymentsProfit After TaxResearch & DevelopmentRestructuring CostsRevenueSelling, General & AdministrativeShares OutstandingShares Outstanding (Diluted Average)Shares Outstanding (Weighted Average)
Others
Ratios

Upstream Bio (UPB) Gross Profit (2024 - 2025)

Upstream Bio has reported Gross Profit over the past 2 years, most recently at -$7.7 million for Q4 2025.

  • Quarterly results put Gross Profit at -$7.7 million for Q4 2025, down 257.43% from a year ago — trailing twelve months through Dec 2025 was -$20.2 million (down 364.92% YoY), and the annual figure for FY2025 was -$20.2 million, down 378.84%.
  • Gross Profit for Q4 2025 was -$7.7 million at Upstream Bio, down from -$1.9 million in the prior quarter.
  • Over the last five years, Gross Profit for UPB hit a ceiling of $289000.0 in Q1 2024 and a floor of -$9.1 million in Q2 2025.