Upstream Bio (UPB) Accumulated Expenses (2023 - 2026)
Upstream Bio (UPB) posted quarterly Accumulated Expenses of $2.2 million for Q1 2026, up 153.14% year-over-year from $875000.0 in Q1 2025, and down 47.16% quarter-over-quarter from $4.2 million in Q4 2025.
Upstream Bio (UPB) Accumulated Expenses (2023 - 2026) Analysis & Trends
Upstream Bio's Accumulated Expenses history runs 4 years deep, the most recent figure standing at $2.2 million for Q1 2026.
- In Q1 2026, Accumulated Expenses rose 153.14% year-over-year to $2.2 million; the TTM figure through Mar 2026 stood at $2.2 million (up 153.14% YoY), while the FY2025 annual figure was $4.2 million, up 55.43% from the prior year.
- Accumulated Expenses for Q1 2026 stood at $2.2 million, down from $4.2 million in the prior quarter.
- The five-year high for Accumulated Expenses was $4.2 million in Q4 2025, with the low at $875000.0 in Q1 2025.
- The 4-year median for Accumulated Expenses is $2.2 million (2023), against an average of $2.4 million.
- The sharpest annual moves came in 2024 and 2026: Accumulated Expenses gained 24.4% in 2024, then soared 153.14% in 2026.
- Upstream Bio's Accumulated Expenses stood at $2.2 million in 2023, then grew by 24.4% to $2.7 million in 2024, then soared by 55.43% to $4.2 million in 2025, then plunged by 47.16% to $2.2 million in 2026.
- Business Quant data shows UPB's Accumulated Expenses at $2.2 million in Q1 2026, $4.2 million in Q4 2025, and $3.0 million in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn |
| 10 | Upstream Bio | 387.23 Mn | 387.23 Mn | -3.29 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 6.95 Mn |
| Mar 31, 2026 | 2.22 Mn |
| Dec 31, 2025 | 4.19 Mn |
| Sep 30, 2025 | 3.04 Mn |
| Jun 30, 2025 | 1.91 Mn |
| Mar 31, 2025 | 875,000.00 |
| Dec 31, 2024 | 2.70 Mn |
| Sep 30, 2024 | 2.00 Mn |
| Dec 31, 2023 | 2.17 Mn |