Upstream Bio (UPB) Accumulated Expenses (2023 - 2026)

Upstream Bio (UPB) recorded quarterly Accumulated Expenses of $11.2 million in Q1 2026, up 168.01% quarter-over-quarter from $4.2 million in Q4 2025, and up 171.31% on a YoY basis from $4.1 million in Q1 2025.

Upstream Bio (UPB) Accumulated Expenses (2023 - 2026) Analysis & Trends

Upstream Bio's Accumulated Expenses history runs 4 years deep, the most recent figure standing at $11.2 million for Q1 2026.

  • In Q1 2026, Accumulated Expenses rose 171.31% year-over-year to $11.2 million; the TTM figure through Mar 2026 stood at $11.2 million (up 171.31% YoY), while the FY2025 annual figure was $4.2 million, down 30.04% from the prior year.
  • Accumulated Expenses was $11.2 million for Q1 2026 at Upstream Bio, up from $4.2 million in the prior quarter.
  • In the past five years, Accumulated Expenses ranged from a high of $11.2 million in Q1 2026 to a low of $1.9 million in Q2 2025.
  • Historically, Accumulated Expenses has averaged $5.6 million across 4 years, with a median of $4.9 million in 2023.
  • The sharpest annual moves came in 2025 and 2026: Accumulated Expenses tumbled 30.04% in 2025, then surged 171.31% in 2026.
  • A 4-year view of Accumulated Expenses shows it stood at $4.5 million in 2023, then jumped by 33.75% to $6.0 million in 2024, then slumped by 30.04% to $4.2 million in 2025, then soared by 168.01% to $11.2 million in 2026.
  • The last three Accumulated Expenses figures came in at $11.2 million (Q1 2026), $4.2 million (Q4 2025), and $7.2 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn -
7 Psyence Biomedical 212.16 Bn 212.16 Bn -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn
9 Abivax 91.96 Bn 91.96 Bn -
10 Upstream Bio 339.03 Mn 339.03 Mn -3.94 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 11.24 Mn
Dec 31, 2025 4.19 Mn
Sep 30, 2025 7.24 Mn
Jun 30, 2025 1.91 Mn
Mar 31, 2025 4.14 Mn
Dec 31, 2024 5.99 Mn
Sep 30, 2024 5.30 Mn
Dec 31, 2023 4.48 Mn