Upstream Bio (UPB) Accumulated Expenses (2023 - 2026)
Upstream Bio (UPB) recorded quarterly Accumulated Expenses of $11.2 million in Q1 2026, up 168.01% quarter-over-quarter from $4.2 million in Q4 2025, and up 171.31% on a YoY basis from $4.1 million in Q1 2025.
Upstream Bio (UPB) Accumulated Expenses (2023 - 2026) Analysis & Trends
Upstream Bio's Accumulated Expenses history runs 4 years deep, the most recent figure standing at $11.2 million for Q1 2026.
- In Q1 2026, Accumulated Expenses rose 171.31% year-over-year to $11.2 million; the TTM figure through Mar 2026 stood at $11.2 million (up 171.31% YoY), while the FY2025 annual figure was $4.2 million, down 30.04% from the prior year.
- Accumulated Expenses was $11.2 million for Q1 2026 at Upstream Bio, up from $4.2 million in the prior quarter.
- In the past five years, Accumulated Expenses ranged from a high of $11.2 million in Q1 2026 to a low of $1.9 million in Q2 2025.
- Historically, Accumulated Expenses has averaged $5.6 million across 4 years, with a median of $4.9 million in 2023.
- The sharpest annual moves came in 2025 and 2026: Accumulated Expenses tumbled 30.04% in 2025, then surged 171.31% in 2026.
- A 4-year view of Accumulated Expenses shows it stood at $4.5 million in 2023, then jumped by 33.75% to $6.0 million in 2024, then slumped by 30.04% to $4.2 million in 2025, then soared by 168.01% to $11.2 million in 2026.
- The last three Accumulated Expenses figures came in at $11.2 million (Q1 2026), $4.2 million (Q4 2025), and $7.2 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - |
| 10 | Upstream Bio | 339.03 Mn | 339.03 Mn | -3.94 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 11.24 Mn |
| Dec 31, 2025 | 4.19 Mn |
| Sep 30, 2025 | 7.24 Mn |
| Jun 30, 2025 | 1.91 Mn |
| Mar 31, 2025 | 4.14 Mn |
| Dec 31, 2024 | 5.99 Mn |
| Sep 30, 2024 | 5.30 Mn |
| Dec 31, 2023 | 4.48 Mn |