Upstream Bio (UPB) Operating Margin: 2023-2025
Historic Operating Margin for Upstream Bio (UPB) over the last 2 years, with Sep 2025 value amounting to -5,539.39%.
- Upstream Bio's Operating Margin fell 242686.00% to -5,539.39% in Q3 2025 from the same period last year, while for Sep 2025 it was -5,020.08%, marking a year-over-year decrease of 203974.00%. This contributed to the annual value of -3,281.18% for FY2024, which is 159572.00% down from last year.
- Upstream Bio's Operating Margin amounted to -5,539.39% in Q3 2025, which was down 17.04% from -4,732.87% recorded in Q2 2025.
- Over the past 5 years, Upstream Bio's Operating Margin peaked at -1,511.43% during Q3 2023, and registered a low of -5,656.01% during Q1 2025.
- Moreover, its 3-year median value for Operating Margin was -3,439.22% (2024), whereas its average is -3,757.22%.
- Data for Upstream Bio's Operating Margin shows a maximum YoY crashed of 331,023bps (in 2025) over the last 5 years.
- Quarterly analysis of 3 years shows Upstream Bio's Operating Margin stood at -3,184.44% in 2023, then slumped by 110,887bps to -4,293.31% in 2024, then crashed by 242,686bps to -5,539.39% in 2025.
- Its Operating Margin stands at -5,539.39% for Q3 2025, versus -4,732.87% for Q2 2025 and -5,656.01% for Q1 2025.