Upstream Bio (UPB) Revenue (2023 - 2026)
Upstream Bio (UPB) recorded Revenue of $773,000 in Q2 2026, down 17.5% from $937,000 a year earlier and down 25.2% from the prior quarter.
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Analysis
Upstream Bio (UPB) Revenue (2023 - 2026) Analysis & Trends
On a TTM basis, Upstream Bio's Revenue came in at $3.16 million as of Jun 30, 2026, up 16.0% year-over-year; for FY2025, it came in at $2.85 million, up 20.4% from FY2024.
- Across earlier years, Revenue came in at $2.37 million in FY2024 (-0.4%) and $2.38 million in FY2023.
- Quarterly Revenue has ranged from $450,000 in Q4 2023 to $1.03 million in Q1 2026 over the past five years.
- On a year-over-year basis, Revenue rose in five of the last eight quarters, with growth averaging 24.1%.
- Peak year-over-year performance for Revenue in the last five years was growth of 83.7% in Q2 2025, against a decline of 17.5% in Q2 2026 at the low end.
- Per Business Quant, the preceding three quarters came in at $1.03 million (Q1 2026), $668,000 (Q4 2025) and $683,000 (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Revenue (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 25.31 Bn |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 16.99 Bn |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 16.61 Bn |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 14.41 Bn |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 15.38 Bn |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 10.05 Bn |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 7.80 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 15.03 Bn |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 3.33 Bn |
| 10 | Upstream Bio | 290.29 Mn | 290.29 Mn | -3.29 Mn | 773,000.00 |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 773,000.00 |
| Mar 31, 2026 | 1.03 Mn |
| Dec 31, 2025 | 668,000.00 |
| Sep 30, 2025 | 683,000.00 |
| Jun 30, 2025 | 937,000.00 |
| Mar 31, 2025 | 566,000.00 |
| Dec 31, 2024 | 613,000.00 |
| Sep 30, 2024 | 607,000.00 |
| Jun 30, 2024 | 510,000.00 |
| Mar 31, 2024 | 640,000.00 |
| Dec 31, 2023 | 450,000.00 |
| Sep 30, 2023 | 621,000.00 |
API Access
Upstream Bio Revenue API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=revenue&ticker=UPB&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "revenue", "ticker": "UPB", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=revenue&ticker=UPB&period=max&api_key=YOUR_API_KEY");
const data = await res.json();