Upstream Bio (UPB) Revenue (2023 - 2026)

Upstream Bio (UPB) posted quarterly Revenue of $1.0 million for Q1 2026, up 82.69% year-over-year from $566000.0 in Q1 2025, and up 54.79% quarter-over-quarter from $668000.0 in Q4 2025.

Upstream Bio (UPB) Revenue (2023 - 2026) Analysis & Trends

Upstream Bio's Revenue history runs 4 years deep, the most recent figure standing at $1.0 million for Q1 2026.

  • In Q1 2026, Revenue rose 82.69% year-over-year to $1.0 million; the TTM figure through Mar 2026 stood at $3.3 million (up 44.69% YoY), while the FY2025 annual figure was $2.9 million, up 20.42% from the prior year.
  • Revenue for Q1 2026 stood at $1.0 million, up from $668000.0 in the prior quarter.
  • The five-year high for Revenue was $1.0 million in Q1 2026, with the low at $450000.0 in Q4 2023.
  • The 4-year median for Revenue is $621000.0 (2023), against an average of $666272.7.
  • Peak annual rise in Revenue reached 83.73% in 2025, while the deepest fall reached 11.56% in 2025.
  • Upstream Bio's Revenue stood at $450000.0 in 2023, then surged by 36.22% to $613000.0 in 2024, then climbed by 8.97% to $668000.0 in 2025, then soared by 54.79% to $1.0 million in 2026.
  • Business Quant data shows UPB's Revenue at $1.0 million in Q1 2026, $668000.0 in Q4 2025, and $683000.0 in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Revenue (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 3.33 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 4.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 1.56 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 1.71 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 3,001.92
7 Royalty Pharma 33.72 Bn 35.84 Bn - 674.14 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 1.29 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 425.49 Mn
10 Upstream Bio 387.23 Mn 387.23 Mn -3.29 Mn 773,000.00

Historic Data

Download Data
DateValue
Jun 30, 2026 773,000.00
Mar 31, 2026 1.03 Mn
Dec 31, 2025 668,000.00
Sep 30, 2025 683,000.00
Jun 30, 2025 937,000.00
Mar 31, 2025 566,000.00
Dec 31, 2024 613,000.00
Sep 30, 2024 607,000.00
Jun 30, 2024 510,000.00
Mar 31, 2024 640,000.00
Dec 31, 2023 450,000.00
Sep 30, 2023 621,000.00