Upstream Bio (UPB) Revenue (2023 - 2026)
Upstream Bio (UPB) recorded quarterly Revenue of $1.0 million in Q1 2026, up 54.79% quarter-over-quarter from $668000.0 in Q4 2025, and up 82.69% on a YoY basis from $566000.0 in Q1 2025.
Upstream Bio (UPB) Revenue (2023 - 2026) Analysis & Trends
Upstream Bio's Revenue history runs 4 years deep, the most recent figure standing at $1.0 million for Q1 2026.
- In Q1 2026, Revenue rose 82.69% year-over-year to $1.0 million; the TTM figure through Mar 2026 stood at $3.3 million (up 44.69% YoY), while the FY2025 annual figure was $2.9 million, up 20.42% from the prior year.
- Revenue was $1.0 million for Q1 2026 at Upstream Bio, up from $668000.0 in the prior quarter.
- In the past five years, Revenue ranged from a high of $1.0 million in Q1 2026 to a low of $450000.0 in Q4 2023.
- Historically, Revenue has averaged $666272.7 across 4 years, with a median of $621000.0 in 2023.
- Biggest YoY gain for Revenue was 83.73% in 2025; the steepest drop was 11.56% in 2025.
- A 4-year view of Revenue shows it stood at $450000.0 in 2023, then soared by 36.22% to $613000.0 in 2024, then grew by 8.97% to $668000.0 in 2025, then jumped by 54.79% to $1.0 million in 2026.
- The last three Revenue figures came in at $1.0 million (Q1 2026), $668000.0 (Q4 2025), and $683000.0 (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Revenue (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 5.21 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 306.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 2.99 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Upstream Bio | 339.03 Mn | 339.03 Mn | -3.94 Mn | 1.03 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 1.03 Mn |
| Dec 31, 2025 | 668,000.00 |
| Sep 30, 2025 | 683,000.00 |
| Jun 30, 2025 | 937,000.00 |
| Mar 31, 2025 | 566,000.00 |
| Dec 31, 2024 | 613,000.00 |
| Sep 30, 2024 | 607,000.00 |
| Jun 30, 2024 | 510,000.00 |
| Mar 31, 2024 | 640,000.00 |
| Dec 31, 2023 | 450,000.00 |
| Sep 30, 2023 | 621,000.00 |