Upstream Bio (UPB) Revenue (2023 - 2026)

Upstream Bio (UPB) recorded quarterly Revenue of $1.0 million in Q1 2026, up 54.79% quarter-over-quarter from $668000.0 in Q4 2025, and up 82.69% on a YoY basis from $566000.0 in Q1 2025.

Upstream Bio (UPB) Revenue (2023 - 2026) Analysis & Trends

Upstream Bio's Revenue history runs 4 years deep, the most recent figure standing at $1.0 million for Q1 2026.

  • In Q1 2026, Revenue rose 82.69% year-over-year to $1.0 million; the TTM figure through Mar 2026 stood at $3.3 million (up 44.69% YoY), while the FY2025 annual figure was $2.9 million, up 20.42% from the prior year.
  • Revenue was $1.0 million for Q1 2026 at Upstream Bio, up from $668000.0 in the prior quarter.
  • In the past five years, Revenue ranged from a high of $1.0 million in Q1 2026 to a low of $450000.0 in Q4 2023.
  • Historically, Revenue has averaged $666272.7 across 4 years, with a median of $621000.0 in 2023.
  • Biggest YoY gain for Revenue was 83.73% in 2025; the steepest drop was 11.56% in 2025.
  • A 4-year view of Revenue shows it stood at $450000.0 in 2023, then soared by 36.22% to $613000.0 in 2024, then grew by 8.97% to $668000.0 in 2025, then jumped by 54.79% to $1.0 million in 2026.
  • The last three Revenue figures came in at $1.0 million (Q1 2026), $668000.0 (Q4 2025), and $683000.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Revenue (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 5.21 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 306.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 2.99 Bn
9 Abivax 91.96 Bn 91.96 Bn - -
10 Upstream Bio 339.03 Mn 339.03 Mn -3.94 Mn 1.03 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 1.03 Mn
Dec 31, 2025 668,000.00
Sep 30, 2025 683,000.00
Jun 30, 2025 937,000.00
Mar 31, 2025 566,000.00
Dec 31, 2024 613,000.00
Sep 30, 2024 607,000.00
Jun 30, 2024 510,000.00
Mar 31, 2024 640,000.00
Dec 31, 2023 450,000.00
Sep 30, 2023 621,000.00