Upstream Bio (UPB) Gains from Investment Securities (2023 - 2026)

Upstream Bio (UPB) recorded quarterly Gains from Investment Securities of $3.1 million in Q1 2026, down 61.06% quarter-over-quarter from $8.0 million in Q4 2025, and up 1450.0% on a YoY basis from $200000.0 in Q1 2025.

Upstream Bio (UPB) Gains from Investment Securities (2023 - 2026) Analysis & Trends

Upstream Bio's Gains from Investment Securities history runs 4 years deep, the most recent figure standing at $3.1 million for Q1 2026.

  • In Q1 2026, Gains from Investment Securities rose 1450.0% year-over-year to $3.1 million; the TTM figure through Mar 2026 stood at $3.3 million (changed N/A YoY), while the FY2025 annual figure was $8.0 million, up 22.65% from the prior year.
  • Gains from Investment Securities was $3.1 million for Q1 2026 at Upstream Bio, down from $8.0 million in the prior quarter.
  • In the past five years, Gains from Investment Securities ranged from a high of $8.3 million in Q2 2025 to a low of $3000.0 in Q4 2023.
  • Historically, Gains from Investment Securities has averaged $4.1 million across 4 years, with a median of $3.1 million in 2026.
  • The sharpest annual moves came in 2025 and 2026: Gains from Investment Securities surged 636.84% in 2025, then soared 1450.0% in 2026.
  • A 4-year view of Gains from Investment Securities shows it stood at $3000.0 in 2023, then soared by 36709.33% to $1.1 million in 2024, then jumped by 620.9% to $8.0 million in 2025, then slumped by 61.06% to $3.1 million in 2026.
  • The last three Gains from Investment Securities figures came in at $3.1 million (Q1 2026), $8.0 million (Q4 2025), and $8.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn -
7 Psyence Biomedical 212.16 Bn 212.16 Bn -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn
9 Abivax 91.96 Bn 91.96 Bn -
10 Upstream Bio 339.03 Mn 339.03 Mn -3.94 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 3.10 Mn
Mar 31, 2026 3.10 Mn
Dec 31, 2025 7.96 Mn
Dec 31, 2025 7.96 Mn
Sep 30, 2025 8.14 Mn
Sep 30, 2025 8.14 Mn
Jun 30, 2025 8.25 Mn
Jun 30, 2025 8.25 Mn
Mar 31, 2025 200,000.00
Mar 31, 2025 200,000.00
Sep 30, 2024 1.10 Mn
Sep 30, 2024 1.10 Mn
Dec 31, 2023 3,000.00
Dec 31, 2023 3,000.00