Upstream Bio (UPB) Market Capitalization (2024 - 2026)
Upstream Bio (UPB) recorded Market Capitalization of $379.02 million in Q2 2026, down 35.8% from $590.7 million a year earlier and down 22.6% from the prior quarter.
Upstream Bio (UPB) Market Capitalization (2024 - 2026) Analysis & Trends
For FY2025, Upstream Bio reported Market Capitalization of $1.47 billion, up 554.7% from FY2024.
- Across earlier years, Market Capitalization came in at $224.94 million in FY2024.
- The Q2 2026 figure is the lowest quarterly Market Capitalization since Q1 2025.
- Per Business Quant, the preceding three quarters came in at $489.78 million (Q1 2026), $1.47 billion (Q4 2025) and $1.02 billion (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn |
| 10 | Upstream Bio | 185.26 Mn | -919.50 Mn | - |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 288.86 Mn |
| Jun 30, 2026 | 379.02 Mn |
| Mar 31, 2026 | 489.78 Mn |
| Dec 31, 2025 | 1.47 Bn |
| Sep 30, 2025 | 1.02 Bn |
| Jun 30, 2025 | 590.70 Mn |
| Mar 31, 2025 | 328.28 Mn |
| Dec 31, 2024 | 224.94 Mn |
Upstream Bio Market Capitalization API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=market-capitalization&ticker=UPB&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "market-capitalization", "ticker": "UPB", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=market-capitalization&ticker=UPB&period=max&api_key=YOUR_API_KEY");
const data = await res.json();