Upstream Bio (UPB) Market Capitalization (2024 - 2026)
Upstream Bio (UPB) recorded Market Capitalization of $379.02 million in Q2 2026, down 35.8% from $590.7 million a year earlier and down 22.6% from the prior quarter.
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Analysis
Upstream Bio (UPB) Market Capitalization (2024 - 2026) Analysis & Trends
For FY2025, Upstream Bio reported Market Capitalization of $1.47 billion, up 554.7% from FY2024.
- Across earlier years, Market Capitalization came in at $224.94 million in FY2024.
- The Q2 2026 figure is the lowest quarterly Market Capitalization since Q1 2025.
- Per Business Quant, the preceding three quarters came in at $489.78 million (Q1 2026), $1.47 billion (Q4 2025) and $1.02 billion (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn |
| 10 | Upstream Bio | 284.26 Mn | 284.26 Mn | -3.29 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 379.02 Mn |
| Mar 31, 2026 | 489.78 Mn |
| Dec 31, 2025 | 1.47 Bn |
| Sep 30, 2025 | 1.02 Bn |
| Jun 30, 2025 | 590.70 Mn |
| Mar 31, 2025 | 328.28 Mn |
| Dec 31, 2024 | 224.94 Mn |
API Access
Upstream Bio Market Capitalization API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=market-capitalization&ticker=UPB&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "market-capitalization", "ticker": "UPB", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=market-capitalization&ticker=UPB&period=max&api_key=YOUR_API_KEY");
const data = await res.json();