Balance Sheet
Cash Flow Statement
Daily Values
Growth Metrics
Income Statement
Consolidated Net IncomeCost of RevenueEBITEBITDAEBTEPS (Basic)EPS (Weighted Average and Diluted)Gross ProfitIncome from Continuing OperationsIncome towards Parent CompanyInterest & Investment IncomeNet Income towards Common StockholdersNon Operating IncomeOperating ExpensesOperating IncomeOther Operating ExpensesPreferred Dividend PaymentsProfit After TaxResearch & DevelopmentRestructuring CostsRevenueSelling, General & AdministrativeShares OutstandingShares Outstanding (Diluted Average)Shares Outstanding (Weighted Average)
Others
Ratios

Upstream Bio (UPB) Operating Expenses (2023 - 2025)

Upstream Bio has reported Operating Expenses over the past 3 years, most recently at $46.8 million for Q4 2025.

  • Quarterly results put Operating Expenses at $46.8 million for Q4 2025, up 73.91% from a year ago — trailing twelve months through Dec 2025 was $163.2 million (up 103.68% YoY), and the annual figure for FY2025 was $163.2 million, up 103.68%.
  • Operating Expenses for Q4 2025 was $46.8 million at Upstream Bio, up from $38.5 million in the prior quarter.
  • Over the last five years, Operating Expenses for UPB hit a ceiling of $46.8 million in Q4 2025 and a floor of $10.0 million in Q3 2023.
  • Median Operating Expenses over the past 3 years was $23.2 million (2024), compared with a mean of $26.8 million.
  • Peak annual rise in Operating Expenses hit 150.88% in 2025, while the deepest fall reached 73.91% in 2025.
  • Upstream Bio's Operating Expenses stood at $14.8 million in 2023, then soared by 82.21% to $26.9 million in 2024, then skyrocketed by 73.91% to $46.8 million in 2025.
  • The last three reported values for Operating Expenses were $46.8 million (Q4 2025), $38.5 million (Q3 2025), and $45.3 million (Q2 2025) per Business Quant data.