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Upstream Bio (UPB) Operating Expenses: 2023-2025

Historic Operating Expenses for Upstream Bio (UPB) over the last 2 years, with Sep 2025 value amounting to $38.5 million.

  • Upstream Bio's Operating Expenses rose 97.52% to $38.5 million in Q3 2025 from the same period last year, while for Sep 2025 it was $143.3 million, marking a year-over-year increase of 110.80%. This contributed to the annual value of $80.1 million for FY2024, which is 88.58% up from last year.
  • Per Upstream Bio's latest filing, its Operating Expenses stood at $38.5 million for Q3 2025, which was down 14.94% from $45.3 million recorded in Q2 2025.
  • Over the past 5 years, Upstream Bio's Operating Expenses peaked at $45.3 million during Q2 2025, and registered a low of $10.0 million during Q3 2023.
  • Over the past 3 years, Upstream Bio's median Operating Expenses value was $19.5 million (recorded in 2024), while the average stood at $24.6 million.
  • Data for Upstream Bio's Operating Expenses shows a peak YoY skyrocketed of 150.88% (in 2025) over the last 5 years.
  • Upstream Bio's Operating Expenses (Quarterly) stood at $14.8 million in 2023, then skyrocketed by 82.21% to $26.9 million in 2024, then soared by 97.52% to $38.5 million in 2025.
  • Its last three reported values are $38.5 million in Q3 2025, $45.3 million for Q2 2025, and $32.6 million during Q1 2025.