Upstream Bio (UPB) Depreciation & Amortization (CF) (2023 - 2026)

Upstream Bio (UPB) recorded quarterly Depreciation & Amortization (CF) of $49000.0 in Q1 2026, down 51.0% quarter-over-quarter from $100000.0 in Q4 2025, and up 13.95% on a YoY basis from $43000.0 in Q1 2025.

Upstream Bio (UPB) Depreciation & Amortization (CF) (2023 - 2026) Analysis & Trends

Upstream Bio's Depreciation & Amortization (CF) history runs 4 years deep, the most recent figure standing at $49000.0 for Q1 2026.

  • In Q1 2026, Depreciation & Amortization (CF) rose 13.95% year-over-year to $49000.0; the TTM figure through Mar 2026 stood at $349000.0 (up 19.52% YoY), while the FY2025 annual figure was $200000.0, up 124.72% from the prior year.
  • Depreciation & Amortization (CF) was $49000.0 for Q1 2026 at Upstream Bio, down from $100000.0 in the prior quarter.
  • In the past five years, Depreciation & Amortization (CF) ranged from a high of $100000.0 in Q3 2023 to a low of $13000.0 in Q1 2024.
  • Historically, Depreciation & Amortization (CF) has averaged $69818.2 across 4 years, with a median of $100000.0 in 2023.
  • Biggest YoY gain for Depreciation & Amortization (CF) was 250.0% in 2024; the steepest drop was 0.0% in 2024.
  • A 4-year view of Depreciation & Amortization (CF) shows it stood at $14000.0 in 2023, then surged by 250.0% to $49000.0 in 2024, then jumped by 104.08% to $100000.0 in 2025, then sank by 51.0% to $49000.0 in 2026.
  • The last three Depreciation & Amortization (CF) figures came in at $49000.0 (Q1 2026), $100000.0 (Q4 2025), and $100000.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Depreciation & Amortization (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 1,395.22
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -1,330.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 55.90 Mn
9 Abivax 91.96 Bn 91.96 Bn - 429,663.65
10 Upstream Bio 339.03 Mn 339.03 Mn -3.94 Mn 49,000.00

Historic Data

Download Data
DateValue
Mar 31, 2026 49,000.00
Mar 31, 2026 49,000.00
Dec 31, 2025 100,000.00
Dec 31, 2025 100,000.00
Sep 30, 2025 100,000.00
Sep 30, 2025 100,000.00
Jun 30, 2025 100,000.00
Jun 30, 2025 100,000.00
Mar 31, 2025 43,000.00
Mar 31, 2025 43,000.00
Dec 31, 2024 49,000.00
Dec 31, 2024 49,000.00
Sep 30, 2024 100,000.00
Sep 30, 2024 100,000.00
Jun 30, 2024 100,000.00
Jun 30, 2024 100,000.00
Mar 31, 2024 13,000.00
Mar 31, 2024 13,000.00
Dec 31, 2023 14,000.00
Dec 31, 2023 14,000.00