Upstream Bio (UPB) Depreciation & Amortization (CF) (2023 - 2026)

Upstream Bio's (UPB) quarterly Depreciation & Amortization (CF) came in at $49000.0 in Q1 2026, up 13.95% year-on-year from $43000.0 in Q1 2025, and down 14.04% quarter-over-quarter from $57000.0 in Q4 2025.

Upstream Bio (UPB) Depreciation & Amortization (CF) (2023 - 2026) Analysis & Trends

Upstream Bio's Depreciation & Amortization (CF) history runs 4 years deep, the most recent figure standing at $49000.0 for Q1 2026.

  • On a quarterly basis, Depreciation & Amortization (CF) rose 13.95% year-over-year to $49000.0 in Q1 2026; TTM through Mar 2026 was $306000.0, a 4.79% increase from a year earlier, with the FY2025 full-year figure at $188000.0, up 111.24% from the prior year.
  • Depreciation & Amortization (CF) slipped to $49000.0 in Q1 2026 per UPB's latest filing, from $57000.0 in the prior quarter.
  • Across five years, Depreciation & Amortization (CF) topped out at $100000.0 in Q3 2023 and bottomed at $13000.0 in Q1 2024.
  • The 4-year median for Depreciation & Amortization (CF) is $57000.0 (2025), against an average of $65909.1.
  • Biggest YoY gain for Depreciation & Amortization (CF) was 250.0% in 2024; the steepest drop was 0.0% in 2024.
  • Year by year, Depreciation & Amortization (CF) stood at $14000.0 in 2023, then surged by 250.0% to $49000.0 in 2024, then climbed by 16.33% to $57000.0 in 2025, then slipped by 14.04% to $49000.0 in 2026.
  • Per Business Quant, the three latest UPB Depreciation & Amortization (CF) figures stand at $49000.0 (Q1 2026), $57000.0 (Q4 2025), and $100000.0 (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Depreciation & Amortization (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - 196,658.72
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 41.14 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 55.90 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 123.20 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - 2.20 Mn
10 Upstream Bio 343.65 Mn 343.65 Mn -3.94 Mn 49,000.00

Historic Data

Download Data
DateValue
Mar 31, 2026 49,000.00
Mar 31, 2026 49,000.00
Dec 31, 2025 57,000.00
Dec 31, 2025 57,000.00
Sep 30, 2025 100,000.00
Sep 30, 2025 100,000.00
Jun 30, 2025 100,000.00
Jun 30, 2025 100,000.00
Mar 31, 2025 43,000.00
Mar 31, 2025 43,000.00
Dec 31, 2024 49,000.00
Dec 31, 2024 49,000.00
Sep 30, 2024 100,000.00
Sep 30, 2024 100,000.00
Jun 30, 2024 100,000.00
Jun 30, 2024 100,000.00
Mar 31, 2024 13,000.00
Mar 31, 2024 13,000.00
Dec 31, 2023 14,000.00
Dec 31, 2023 14,000.00