Upstream Bio (UPB) Depreciation & Amortization (CF) (2023 - 2026)

Upstream Bio (UPB) posted quarterly Depreciation & Amortization (CF) of $49000.0 for Q1 2026, up 13.95% year-over-year from $43000.0 in Q1 2025, and down 14.04% quarter-over-quarter from $57000.0 in Q4 2025.

Upstream Bio (UPB) Depreciation & Amortization (CF) (2023 - 2026) Analysis & Trends

Upstream Bio's Depreciation & Amortization (CF) history runs 4 years deep, the most recent figure standing at $49000.0 for Q1 2026.

  • In Q1 2026, Depreciation & Amortization (CF) rose 13.95% year-over-year to $49000.0; the TTM figure through Mar 2026 stood at $306000.0 (up 4.79% YoY), while the FY2025 annual figure was $188000.0, up 111.24% from the prior year.
  • Depreciation & Amortization (CF) for Q1 2026 stood at $49000.0, down from $57000.0 in the prior quarter.
  • The five-year high for Depreciation & Amortization (CF) was $100000.0 in Q3 2023, with the low at $13000.0 in Q1 2024.
  • The 4-year median for Depreciation & Amortization (CF) is $57000.0 (2025), against an average of $65909.1.
  • Peak annual rise in Depreciation & Amortization (CF) reached 250.0% in 2024, while the deepest fall reached 0.0% in 2024.
  • Upstream Bio's Depreciation & Amortization (CF) stood at $14000.0 in 2023, then jumped by 250.0% to $49000.0 in 2024, then advanced by 16.33% to $57000.0 in 2025, then decreased by 14.04% to $49000.0 in 2026.
  • Business Quant data shows UPB's Depreciation & Amortization (CF) at $49000.0 in Q1 2026, $57000.0 in Q4 2025, and $100000.0 in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Depreciation & Amortization (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 56.50 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 123.70 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - 2.10 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 40.52 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -
7 Royalty Pharma 33.72 Bn 35.84 Bn - -
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 3.18 Mn
10 Upstream Bio 387.23 Mn 387.23 Mn -3.29 Mn 100,000.00

Historic Data

Download Data
DateValue
Jun 30, 2026 100,000.00
Jun 30, 2026 100,000.00
Mar 31, 2026 49,000.00
Mar 31, 2026 49,000.00
Dec 31, 2025 57,000.00
Dec 31, 2025 57,000.00
Sep 30, 2025 100,000.00
Sep 30, 2025 100,000.00
Jun 30, 2025 100,000.00
Jun 30, 2025 100,000.00
Mar 31, 2025 43,000.00
Mar 31, 2025 43,000.00
Dec 31, 2024 49,000.00
Dec 31, 2024 49,000.00
Sep 30, 2024 100,000.00
Sep 30, 2024 100,000.00
Jun 30, 2024 100,000.00
Jun 30, 2024 100,000.00
Mar 31, 2024 13,000.00
Mar 31, 2024 13,000.00