Upstream Bio UPB
NASDAQ UPB
$6.01 -0.07 (-1.15%)
As of: Sep 4, 2026 · 3:59 PM EDT

Upstream Bio (UPB) Depreciation & Amortization (CF) (2023 - 2026)

Upstream Bio (UPB) posted quarterly Depreciation & Amortization (CF) of $49000.0 for Q1 2026, up 13.95% year-over-year from $43000.0 in Q1 2025, and down 14.04% quarter-over-quarter from $57000.0 in Q4 2025.

Analysis

Upstream Bio (UPB) Depreciation & Amortization (CF) (2023 - 2026) Analysis & Trends

Upstream Bio's Depreciation & Amortization (CF) history runs 4 years deep, the most recent figure standing at $49000.0 for Q1 2026.

  • In Q1 2026, Depreciation & Amortization (CF) rose 13.95% year-over-year to $49000.0; the TTM figure through Mar 2026 stood at $306000.0 (up 4.79% YoY), while the FY2025 annual figure was $188000.0, up 111.24% from the prior year.
  • Depreciation & Amortization (CF) for Q1 2026 stood at $49000.0, down from $57000.0 in the prior quarter.
  • The five-year high for Depreciation & Amortization (CF) was $100000.0 in Q3 2023, with the low at $13000.0 in Q1 2024.
  • The 4-year median for Depreciation & Amortization (CF) is $57000.0 (2025), against an average of $65909.1.
  • Peak annual rise in Depreciation & Amortization (CF) reached 250.0% in 2024, while the deepest fall reached 0.0% in 2024.
  • Upstream Bio's Depreciation & Amortization (CF) stood at $14000.0 in 2023, then jumped by 250.0% to $49000.0 in 2024, then advanced by 16.33% to $57000.0 in 2025, then decreased by 14.04% to $49000.0 in 2026.
  • Business Quant data shows UPB's Depreciation & Amortization (CF) at $49000.0 in Q1 2026, $57000.0 in Q4 2025, and $100000.0 in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Depreciation & Amortization (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 56.50 Mn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 123.70 Mn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -
5 Revolution Medicines 44.33 Bn 44.33 Bn - -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 40.52 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn -
8 Royalty Pharma 28.45 Bn 27.61 Bn - -
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -
10 Upstream Bio 327.95 Mn 327.95 Mn -3.29 Mn 100,000.00
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 100,000.00
Mar 31, 2026 49,000.00
Dec 31, 2025 69,000.00
Sep 30, 2025 100,000.00
Jun 30, 2025 100,000.00
Mar 31, 2025 43,000.00
Dec 31, 2024 49,000.00
Sep 30, 2024 100,000.00
Jun 30, 2024 100,000.00
Mar 31, 2024 13,000.00
Dec 31, 2023 14,000.00
Sep 30, 2023 100,000.00