Upstream Bio (UPB) Non-cash Items (2023 - 2026)
Upstream Bio's quarterly Non-cash Items came in at $43.4 million in Q1 2026, up 1879.22% year-on-year from $2.2 million in Q1 2025, and down 73.26% quarter-over-quarter from $162.3 million in Q4 2025.
Upstream Bio has reported Non-cash Items for 4 years, with the latest figure at $43.4 million in Q1 2026.
- For the quarter ending Q1 2026, Non-cash Items rose 1879.22% year-over-year to $43.4 million; the trailing twelve-month figure through Mar 2026 stood at $43.4 million (up 1879.22% YoY), and the FY2025 full-year result was $162.3 million, up 127.71% from the prior year.
- Non-cash Items for Q1 2026 stood at $43.4 million, down from $162.3 million in the prior quarter.
- The five-year high for Non-cash Items was $162.3 million in Q4 2025, with the low at $2.2 million in Q1 2025.
- Average Non-cash Items over 4 years is $45.2 million, with a median of $37.4 million recorded in 2024.
- Year-over-year, Non-cash Items slumped 90.39% in 2025 and soared 1879.22% in 2026.
- Tracing UPB's Non-cash Items over 4 years: stood at $4.6 million in 2023, then soared by 1433.26% to $71.3 million in 2024, then jumped by 127.71% to $162.3 million in 2025, then slumped by 73.26% to $43.4 million in 2026.
- The last three Non-cash Items figures came in at $43.4 million (Q1 2026), $162.3 million (Q4 2025), and $3.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn |
| 10 | Upstream Bio | 454.22 Mn | 454.22 Mn | -3.94 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 43.40 Mn |
| Mar 31, 2026 | 43.40 Mn |
| Dec 31, 2025 | 162.28 Mn |
| Dec 31, 2025 | 162.28 Mn |
| Sep 30, 2025 | 3.37 Mn |
| Sep 30, 2025 | 3.37 Mn |
| Jun 30, 2025 | 39.69 Mn |
| Jun 30, 2025 | 39.69 Mn |
| Mar 31, 2025 | 2.19 Mn |
| Mar 31, 2025 | 2.19 Mn |
| Dec 31, 2024 | 71.27 Mn |
| Dec 31, 2024 | 71.27 Mn |
| Sep 30, 2024 | 35.09 Mn |
| Sep 30, 2024 | 35.09 Mn |
| Dec 31, 2023 | 4.65 Mn |
| Dec 31, 2023 | 4.65 Mn |