Upstream Bio (UPB) Non-cash Items (2023 - 2026)

Upstream Bio (UPB) recorded quarterly Non-cash Items of $3.9 million in Q1 2026, down 97.57% quarter-over-quarter from $162.3 million in Q4 2025, and down 83.12% on a YoY basis from $23.4 million in Q1 2025.

Upstream Bio (UPB) Non-cash Items (2023 - 2026) Analysis & Trends

Upstream Bio's Non-cash Items history runs 4 years deep, the most recent figure standing at $3.9 million for Q1 2026.

  • In Q1 2026, Non-cash Items fell 83.12% year-over-year to $3.9 million; the TTM figure through Mar 2026 stood at $3.9 million (down 83.12% YoY), while the FY2025 annual figure was $162.3 million, up 8041.21% from the prior year.
  • Non-cash Items was $3.9 million for Q1 2026 at Upstream Bio, down from $162.3 million in the prior quarter.
  • In the past five years, Non-cash Items ranged from a high of $162.3 million in Q4 2025 to a low of $3.9 million in Q1 2026.
  • Historically, Non-cash Items has averaged $55.0 million across 4 years, with a median of $37.4 million in 2024.
  • The sharpest annual moves came in 2024 and 2026: Non-cash Items jumped 1433.26% in 2024, then sank 83.12% in 2026.
  • A 4-year view of Non-cash Items shows it stood at $4.6 million in 2023, then surged by 1433.26% to $71.3 million in 2024, then soared by 127.71% to $162.3 million in 2025, then slumped by 97.57% to $3.9 million in 2026.
  • The last three Non-cash Items figures came in at $3.9 million (Q1 2026), $162.3 million (Q4 2025), and $99.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn -
7 Psyence Biomedical 212.16 Bn 212.16 Bn -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn
9 Abivax 91.96 Bn 91.96 Bn -
10 Upstream Bio 339.03 Mn 339.03 Mn -3.94 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 3.95 Mn
Mar 31, 2026 3.95 Mn
Dec 31, 2025 162.28 Mn
Dec 31, 2025 162.28 Mn
Sep 30, 2025 99.54 Mn
Sep 30, 2025 99.54 Mn
Jun 30, 2025 39.69 Mn
Jun 30, 2025 39.69 Mn
Mar 31, 2025 23.40 Mn
Mar 31, 2025 23.40 Mn
Dec 31, 2024 71.27 Mn
Dec 31, 2024 71.27 Mn
Sep 30, 2024 35.09 Mn
Sep 30, 2024 35.09 Mn
Dec 31, 2023 4.65 Mn
Dec 31, 2023 4.65 Mn