Upstream Bio (UPB) Enterprise Value (2023 - 2025)

Historic Enterprise Value for Upstream Bio (UPB) over the last 3 years, with Q3 2025 value amounting to -$372.4 million.

  • Upstream Bio's Enterprise Value fell 6877.94% to -$372.4 million in Q3 2025 from the same period last year, while for Sep 2025 it was -$372.4 million, marking a year-over-year decrease of 6877.94%. This contributed to the annual value of -$470.5 million for FY2024, which is 32842.27% down from last year.
  • According to the latest figures from Q3 2025, Upstream Bio's Enterprise Value is -$372.4 million, which was down 6877.94% from -$393.6 million recorded in Q2 2025.
  • In the past 5 years, Upstream Bio's Enterprise Value ranged from a high of -$31.5 million in Q1 2024 and a low of -$470.5 million during Q4 2024
  • In the last 3 years, Upstream Bio's Enterprise Value had a median value of -$220.7 million in 2024 and averaged -$236.1 million.
  • Examining YoY changes over the last 5 years, Upstream Bio's Enterprise Value showed a top increase of 6877.94% in 2025 and a maximum decrease of 126902.57% in 2025.
  • Upstream Bio's Enterprise Value (Quarter) stood at -$109.8 million in 2023, then crashed by 328.42% to -$470.5 million in 2024, then increased by 20.84% to -$372.4 million in 2025.
  • Its Enterprise Value was -$372.4 million in Q3 2025, compared to -$393.6 million in Q2 2025 and -$431.4 million in Q1 2025.