Upstream Bio (UPB) Enterprise Value (2023 - 2025)
Upstream Bio has reported Enterprise Value over the past 3 years, most recently at -$341.5 million for Q4 2025.
- Quarterly results put Enterprise Value at -$341.5 million for Q4 2025, up 26.65% from a year ago — trailing twelve months through Dec 2025 was -$341.5 million (up 26.65% YoY), and the annual figure for FY2025 was -$341.5 million, up 26.65%.
- Enterprise Value for Q4 2025 was -$341.5 million at Upstream Bio, up from -$372.4 million in the prior quarter.
- Over the last five years, Enterprise Value for UPB hit a ceiling of -$31.5 million in Q1 2024 and a floor of -$465.6 million in Q4 2024.
- Median Enterprise Value over the past 3 years was -$281.1 million (2024), compared with a mean of -$245.9 million.
- Peak annual rise in Enterprise Value hit 26.65% in 2025, while the deepest fall reached 1269.03% in 2025.
- Upstream Bio's Enterprise Value stood at -$107.3 million in 2023, then crashed by 333.98% to -$465.6 million in 2024, then grew by 26.65% to -$341.5 million in 2025.
- The last three reported values for Enterprise Value were -$341.5 million (Q4 2025), -$372.4 million (Q3 2025), and -$393.6 million (Q2 2025) per Business Quant data.