Upstream Bio (UPB) Enterprise Value (2024 - 2026)
Upstream Bio (UPB) recorded Enterprise Value of $117.71 million in Q2 2026, down 40.3% from $197.12 million a year earlier and down 39.7% from the prior quarter.
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Analysis
Upstream Bio (UPB) Enterprise Value (2024 - 2026) Analysis & Trends
On a TTM basis, Upstream Bio's Enterprise Value came in at -$890.81 million as of Jun 30, 2026; for FY2025, it came in at $1.13 billion.
- Across earlier years, Enterprise Value came in at -$245.51 million in FY2024.
- The Q2 2026 figure is the lowest quarterly Enterprise Value since Q1 2025.
- Per Business Quant, the preceding three quarters came in at $195.2 million (Q1 2026), $1.13 billion (Q4 2025) and $643.3 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn |
| 10 | Upstream Bio | 290.29 Mn | 290.29 Mn | -3.29 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 117.71 Mn |
| Mar 31, 2026 | 195.20 Mn |
| Dec 31, 2025 | 1.13 Bn |
| Sep 30, 2025 | 643.30 Mn |
| Jun 30, 2025 | 197.12 Mn |
| Mar 31, 2025 | -103.10 Mn |
| Dec 31, 2024 | -245.51 Mn |
API Access
Upstream Bio Enterprise Value API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=enterprise-value&ticker=UPB&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "enterprise-value", "ticker": "UPB", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=enterprise-value&ticker=UPB&period=max&api_key=YOUR_API_KEY");
const data = await res.json();