Upstream Bio (UPB) Enterprise Value: 2023-2025
Historic Enterprise Value for Upstream Bio (UPB) over the last 2 years, with Sep 2025 value amounting to $641.6 million.
- Upstream Bio's Enterprise Value fell 47.73% to $641.6 million in Q3 2025 from the same period last year, while for Sep 2025 it was -$653.8 million, marking a year-over-year decrease of 162.93%. This contributed to the annual value of $410.7 million for FY2024, which is 473.99% up from last year.
- Latest data reveals that Upstream Bio reported Enterprise Value of $641.6 million as of Q3 2025, which was up 225.57% from $197.1 million recorded in Q2 2025.
- Over the past 5 years, Upstream Bio's Enterprise Value peaked at $1.2 billion during Q3 2024, and registered a low of -$109.8 million during Q4 2023.
- Moreover, its 3-year median value for Enterprise Value was -$31.5 million (2024), whereas its average is $237.5 million.
- Per our database at Business Quant, Upstream Bio's Enterprise Value soared by 2,694.19% in 2024 and then tumbled by 227.19% in 2025.
- Over the past 3 years, Upstream Bio's Enterprise Value (Quarterly) stood at -$109.8 million in 2023, then surged by 473.99% to $410.7 million in 2024, then tumbled by 47.73% to $641.6 million in 2025.
- Its Enterprise Value stands at $641.6 million for Q3 2025, versus $197.1 million for Q2 2025 and -$103.1 million for Q1 2025.