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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInvested CapitalMarket CapitalizationNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Sales

Upstream Bio (UPB) Net Margin: 2023-2025

Historic Net Margin for Upstream Bio (UPB) over the last 2 years, with Sep 2025 value amounting to -4,941.14%.

  • Upstream Bio's Net Margin fell 147607.00% to -4,941.14% in Q3 2025 from the same period last year, while for Sep 2025 it was -4,386.35%, marking a year-over-year decrease of 123325.00%. This contributed to the annual value of -3,223.42% for FY2024, which is 161606.00% down from last year.
  • Upstream Bio's Net Margin amounted to -4,941.14% in Q3 2025, which was down 15.84% from -4,265.31% recorded in Q2 2025.
  • Over the past 5 years, Upstream Bio's Net Margin peaked at -1,006.92% during Q3 2023, and registered a low of -4,941.14% during Q3 2025.
  • For the 3-year period, Upstream Bio's Net Margin averaged around -3,489.52%, with its median value being -3,554.65% (2024).
  • Data for Upstream Bio's Net Margin shows a maximum YoY plummeted of 262,896bps (in 2025) over the last 5 years.
  • Quarterly analysis of 3 years shows Upstream Bio's Net Margin stood at -3,329.78% in 2023, then slumped by 22,487bps to -3,554.65% in 2024, then tumbled by 147,607bps to -4,941.14% in 2025.
  • Its last three reported values are -4,941.14% in Q3 2025, -4,265.31% for Q2 2025, and -4,818.02% during Q1 2025.