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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Sales

Upstream Bio (UPB) Net Margin (2023 - 2025)

Upstream Bio has reported Net Margin over the past 3 years, most recently at 6356.14% for Q4 2025.

  • Quarterly results put Net Margin at 6356.14% for Q4 2025, down 280149.0% from a year ago — trailing twelve months through Dec 2025 was 5026.03% (down 180262.0% YoY), and the annual figure for FY2025 was 5026.03%, down 180262.0%.
  • Net Margin for Q4 2025 was 6356.14% at Upstream Bio, down from 4941.14% in the prior quarter.
  • Over the last five years, Net Margin for UPB hit a ceiling of 1006.92% in Q3 2023 and a floor of 6356.14% in Q4 2025.
  • Median Net Margin over the past 3 years was 3695.17% (2024), compared with a mean of 3776.18%.
  • Biggest five-year swings in Net Margin: crashed -22487bps in 2024 and later plummeted -280149bps in 2025.
  • Upstream Bio's Net Margin stood at 3329.78% in 2023, then fell by -7bps to 3554.65% in 2024, then tumbled by -79bps to 6356.14% in 2025.
  • The last three reported values for Net Margin were 6356.14% (Q4 2025), 4941.14% (Q3 2025), and 4265.31% (Q2 2025) per Business Quant data.