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Upstream Bio (UPB) Profit After Tax (2023 - 2025)

Upstream Bio (UPB) has 3 years of Profit After Tax data on record, last reported at -$36.3 million in Q3 2025.

  • For Q3 2025, Profit After Tax fell 126.81% year-over-year to -$36.3 million; the TTM value through Sep 2025 reached -$124.7 million, down 133.79%, while the annual FY2024 figure was -$62.8 million, 206.37% down from the prior year.
  • Profit After Tax reached -$36.3 million in Q3 2025 per UPB's latest filing, up from -$40.0 million in the prior quarter.
  • Across five years, Profit After Tax topped out at -$3.1 million in Q3 2023 and bottomed at -$40.0 million in Q2 2025.
  • Average Profit After Tax over 3 years is -$20.1 million, with a median of -$16.0 million recorded in 2024.
  • The widest YoY moves for Profit After Tax: up 80.08% in 2024, down 415.54% in 2024.
  • A 3-year view of Profit After Tax shows it stood at -$11.8 million in 2023, then plummeted by 80.08% to -$21.2 million in 2024, then tumbled by 70.75% to -$36.3 million in 2025.
  • Per Business Quant database, its latest 3 readings for Profit After Tax were -$36.3 million in Q3 2025, -$40.0 million in Q2 2025, and -$27.3 million in Q1 2025.