Upstream Bio (UPB) Profit After Tax (2023 - 2026)

Upstream Bio's Profit After Tax history runs 4 years deep, the most recent figure standing at -$40.6 million for Q1 2026.

• In Q1 2026, Profit After Tax fell 48.68% year-over-year to -$40.6 million; the TTM figure through Mar 2026 stood at -$156.7 million (down 97.99% YoY), while the FY2025 annual figure was -$143.4 million, down 128.41% from the prior year.
• Profit After Tax for Q1 2026 stood at -$40.6 million, up from -$42.4 million in the prior quarter.
• The five-year high for Profit After Tax was -$3.1 million in Q3 2023, with the low at -$42.4 million in Q4 2025.
• The 4-year median for Profit After Tax is -$21.2 million (2024), against an average of -$23.8 million.
• The sharpest annual moves came in 2024 and 2026: Profit After Tax plunged 415.54% in 2024, then sank 48.68% in 2026.
• Upstream Bio's Profit After Tax stood at -$11.8 million in 2023, then tumbled by 79.16% to -$21.2 million in 2024, then slumped by 100.2% to -$42.4 million in 2025, then rose by 4.36% to -$40.6 million in 2026.
• Business Quant data shows UPB's Profit After Tax at -$40.6 million in Q1 2026, -$42.4 million in Q4 2025, and -$33.7 million in Q3 2025.