Upstream Bio (UPB) Profit After Tax (2023 - 2026)

Upstream Bio's Profit After Tax history runs 4 years deep, the most recent figure standing at -$40.6 million for Q1 2026.

• On a quarterly basis, Profit After Tax fell 48.68% year-over-year to -$40.6 million in Q1 2026; TTM through Mar 2026 was -$156.7 million, a 97.99% decrease from a year earlier, with the FY2025 full-year figure at -$143.4 million, down 128.41% from the prior year.
• Profit After Tax climbed to -$40.6 million in Q1 2026 per UPB's latest filing, from -$42.4 million in the prior quarter.
• Across five years, Profit After Tax topped out at -$3.1 million in Q3 2023 and bottomed at -$42.4 million in Q4 2025.
• The 4-year median for Profit After Tax is -$21.2 million (2024), against an average of -$23.8 million.
• Across the five-year window, Profit After Tax sank 415.54% in 2024 and slumped 48.68% in 2026, its largest moves.
• Year by year, Profit After Tax stood at -$11.8 million in 2023, then slumped by 79.16% to -$21.2 million in 2024, then sank by 100.2% to -$42.4 million in 2025, then gained by 4.36% to -$40.6 million in 2026.
• Per Business Quant, the three latest UPB Profit After Tax figures stand at -$40.6 million (Q1 2026), -$42.4 million (Q4 2025), and -$33.7 million (Q3 2025).