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Consolidated Net IncomeCost of RevenueEBITEBITDAEBTEPS (Basic)EPS (Weighted Average and Diluted)Gross ProfitIncome from Continuing OperationsIncome towards Parent CompanyInterest & Investment IncomeNet Income towards Common StockholdersNon Operating IncomeOperating ExpensesOperating IncomeOther Operating ExpensesPreferred Dividend PaymentsProfit After TaxResearch & DevelopmentRestructuring CostsRevenueSelling, General & AdministrativeShares OutstandingShares Outstanding (Diluted Average)Shares Outstanding (Weighted Average)
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Upstream Bio (UPB) Profit After Tax (2023 - 2025)

Upstream Bio has reported Profit After Tax over the past 3 years, most recently at -$42.4 million for Q4 2025.

  • Quarterly results put Profit After Tax at -$42.4 million for Q4 2025, down 99.68% from a year ago — trailing twelve months through Dec 2025 was -$143.4 million (down 128.32% YoY), and the annual figure for FY2025 was -$143.4 million, down 128.32%.
  • Profit After Tax for Q4 2025 was -$42.4 million at Upstream Bio, down from -$33.7 million in the prior quarter.
  • Over the last five years, Profit After Tax for UPB hit a ceiling of -$3.1 million in Q3 2023 and a floor of -$42.4 million in Q4 2025.
  • Median Profit After Tax over the past 3 years was -$18.6 million (2024), compared with a mean of -$22.1 million.
  • Peak annual rise in Profit After Tax hit 80.02% in 2024, while the deepest fall reached 415.54% in 2024.
  • Upstream Bio's Profit After Tax stood at -$11.8 million in 2023, then plummeted by 80.02% to -$21.2 million in 2024, then crashed by 99.68% to -$42.4 million in 2025.
  • The last three reported values for Profit After Tax were -$42.4 million (Q4 2025), -$33.7 million (Q3 2025), and -$40.0 million (Q2 2025) per Business Quant data.