Upstream Bio (UPB) Change in Accured Expenses (2023 - 2026)
Upstream Bio's (UPB) quarterly Change in Accured Expenses came in at $1.2 million in Q1 2026, up 166.4% year-on-year from $461342.3 in Q1 2025, and down 56.43% quarter-over-quarter from $2.8 million in Q4 2025.
Upstream Bio (UPB) Change in Accured Expenses (2023 - 2026) Analysis & Trends
Upstream Bio's Change in Accured Expenses history runs 4 years deep, the most recent figure standing at $1.2 million for Q1 2026.
- On a quarterly basis, Change in Accured Expenses rose 166.4% year-over-year to $1.2 million in Q1 2026; TTM through Mar 2026 was $7.1 million, a 1201.65% increase from a year earlier, with the FY2025 full-year figure at $4.0 million, up 165.48% from the prior year.
- Change in Accured Expenses retreated to $1.2 million in Q1 2026 per UPB's latest filing, from $2.8 million in the prior quarter.
- Across five years, Change in Accured Expenses topped out at $3.5 million in Q2 2025 and bottomed at -$1.9 million in Q1 2025.
- The 4-year median for Change in Accured Expenses is $510500.0 (2023), against an average of $739400.0.
- Biggest YoY gain for Change in Accured Expenses was 822.77% in 2025; the steepest drop was 285.71% in 2025.
- Year by year, Change in Accured Expenses stood at $639000.0 in 2023, then surged by 174.65% to $1.8 million in 2024, then surged by 60.74% to $2.8 million in 2025, then sank by 56.43% to $1.2 million in 2026.
- Per Business Quant, the three latest UPB Change in Accured Expenses figures stand at $1.2 million (Q1 2026), $2.8 million (Q4 2025), and -$481000.0 (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Accured Expenses (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | 1.13 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | -16.82 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 23.10 Mn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 107.70 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -16.74 Mn |
| 10 | Upstream Bio | 347.73 Mn | 347.73 Mn | -3.94 Mn | 1.23 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 1.23 Mn |
| Mar 31, 2026 | 1.23 Mn |
| Dec 31, 2025 | 2.82 Mn |
| Dec 31, 2025 | 2.82 Mn |
| Sep 30, 2025 | -481,000.00 |
| Sep 30, 2025 | -481,000.00 |
| Jun 30, 2025 | 3.53 Mn |
| Jun 30, 2025 | 3.53 Mn |
| Mar 31, 2025 | -1.85 Mn |
| Mar 31, 2025 | -1.85 Mn |
| Dec 31, 2024 | 1.76 Mn |
| Dec 31, 2024 | 1.76 Mn |
| Sep 30, 2024 | 259,000.00 |
| Sep 30, 2024 | 259,000.00 |
| Jun 30, 2024 | 382,000.00 |
| Jun 30, 2024 | 382,000.00 |
| Mar 31, 2024 | -884,000.00 |
| Mar 31, 2024 | -884,000.00 |
| Dec 31, 2023 | 639,000.00 |
| Dec 31, 2023 | 639,000.00 |