Upstream Bio (UPB) Change in Accured Expenses (2023 - 2026)

Upstream Bio (UPB) recorded quarterly Change in Accured Expenses of $1.2 million in Q1 2026, down 56.43% quarter-over-quarter from $2.8 million in Q4 2025, and up 166.4% on a YoY basis from $461342.3 in Q1 2025.

Upstream Bio (UPB) Change in Accured Expenses (2023 - 2026) Analysis & Trends

Upstream Bio's Change in Accured Expenses history runs 4 years deep, the most recent figure standing at $1.2 million for Q1 2026.

  • In Q1 2026, Change in Accured Expenses rose 166.4% year-over-year to $1.2 million; the TTM figure through Mar 2026 stood at $7.1 million (up 1201.65% YoY), while the FY2025 annual figure was $4.0 million, up 165.48% from the prior year.
  • Change in Accured Expenses was $1.2 million for Q1 2026 at Upstream Bio, down from $2.8 million in the prior quarter.
  • In the past five years, Change in Accured Expenses ranged from a high of $3.5 million in Q2 2025 to a low of -$1.9 million in Q1 2025.
  • Historically, Change in Accured Expenses has averaged $739400.0 across 4 years, with a median of $510500.0 in 2023.
  • Biggest YoY gain for Change in Accured Expenses was 822.77% in 2025; the steepest drop was 285.71% in 2025.
  • A 4-year view of Change in Accured Expenses shows it stood at $639000.0 in 2023, then surged by 174.65% to $1.8 million in 2024, then surged by 60.74% to $2.8 million in 2025, then tumbled by 56.43% to $1.2 million in 2026.
  • The last three Change in Accured Expenses figures came in at $1.2 million (Q1 2026), $2.8 million (Q4 2025), and -$481000.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Accured Expenses (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 931,000.00
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 644,700.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 70.50 Mn
9 Abivax 91.96 Bn 91.96 Bn - -
10 Upstream Bio 339.03 Mn 339.03 Mn -3.94 Mn 1.23 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 1.23 Mn
Mar 31, 2026 1.23 Mn
Dec 31, 2025 2.82 Mn
Dec 31, 2025 2.82 Mn
Sep 30, 2025 -481,000.00
Sep 30, 2025 -481,000.00
Jun 30, 2025 3.53 Mn
Jun 30, 2025 3.53 Mn
Mar 31, 2025 -1.85 Mn
Mar 31, 2025 -1.85 Mn
Dec 31, 2024 1.76 Mn
Dec 31, 2024 1.76 Mn
Sep 30, 2024 259,000.00
Sep 30, 2024 259,000.00
Jun 30, 2024 382,000.00
Jun 30, 2024 382,000.00
Mar 31, 2024 -884,000.00
Mar 31, 2024 -884,000.00
Dec 31, 2023 639,000.00
Dec 31, 2023 639,000.00