Upstream Bio (UPB) Change in Accured Expenses (2023 - 2026)
Upstream Bio's quarterly Change in Accured Expenses came in at $1.2 million in Q1 2026, up 166.4% year-on-year from $461342.3 in Q1 2025, and down 56.43% quarter-over-quarter from $2.8 million in Q4 2025.
Upstream Bio has reported Change in Accured Expenses for 4 years, with the latest figure at $1.2 million in Q1 2026.
- For the quarter ending Q1 2026, Change in Accured Expenses rose 166.4% year-over-year to $1.2 million; the trailing twelve-month figure through Mar 2026 stood at $7.1 million (up 1201.65% YoY), and the FY2025 full-year result was $4.0 million, up 165.48% from the prior year.
- Change in Accured Expenses for Q1 2026 stood at $1.2 million, down from $2.8 million in the prior quarter.
- The five-year high for Change in Accured Expenses was $3.5 million in Q2 2025, with the low at -$1.9 million in Q1 2025.
- Average Change in Accured Expenses over 4 years is $739400.0, with a median of $510500.0 recorded in 2023.
- Peak annual rise in Change in Accured Expenses reached 822.77% in 2025, while the deepest fall reached 285.71% in 2025.
- Tracing UPB's Change in Accured Expenses over 4 years: stood at $639000.0 in 2023, then soared by 174.65% to $1.8 million in 2024, then soared by 60.74% to $2.8 million in 2025, then slumped by 56.43% to $1.2 million in 2026.
- The last three Change in Accured Expenses figures came in at $1.2 million (Q1 2026), $2.8 million (Q4 2025), and -$481000.0 (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Accured Expenses (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | - |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | - |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | 931,000.00 |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 70.50 Mn |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | 107.70 Mn |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | -176.03 Mn |
| 10 | Upstream Bio | 454.22 Mn | 454.22 Mn | -3.94 Mn | 1.23 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 1.23 Mn |
| Mar 31, 2026 | 1.23 Mn |
| Dec 31, 2025 | 2.82 Mn |
| Dec 31, 2025 | 2.82 Mn |
| Sep 30, 2025 | -481,000.00 |
| Sep 30, 2025 | -481,000.00 |
| Jun 30, 2025 | 3.53 Mn |
| Jun 30, 2025 | 3.53 Mn |
| Mar 31, 2025 | -1.85 Mn |
| Mar 31, 2025 | -1.85 Mn |
| Dec 31, 2024 | 1.76 Mn |
| Dec 31, 2024 | 1.76 Mn |
| Sep 30, 2024 | 259,000.00 |
| Sep 30, 2024 | 259,000.00 |
| Jun 30, 2024 | 382,000.00 |
| Jun 30, 2024 | 382,000.00 |
| Mar 31, 2024 | -884,000.00 |
| Mar 31, 2024 | -884,000.00 |
| Dec 31, 2023 | 639,000.00 |
| Dec 31, 2023 | 639,000.00 |