Upstream Bio (UPB) Return on Assets (2024 - 2026)

Upstream Bio's (UPB) quarterly Return on Assets came in at 0.01% in Q1 2026, down 1.0% year-on-year from 0.01% in Q1 2025, and down 17.42% quarter-over-quarter from 0.01% in Q4 2025.

Upstream Bio (UPB) Return on Assets (2024 - 2026) Analysis & Trends

Upstream Bio's Return on Assets history runs 3 years deep, the most recent figure standing at 0.01% for Q1 2026.

  • On a quarterly basis, Return on Assets fell 1.0% year-over-year to 0.01% in Q1 2026; TTM through Mar 2026 was 0.01%, a 1.0% decrease from a year earlier, with the FY2025 full-year figure at 0.01%, changed 0.0% from the prior year.
  • Return on Assets declined to 0.01% in Q1 2026 per UPB's latest filing, from 0.01% in the prior quarter.
  • Across five years, Return on Assets topped out at 0.0% in Q1 2025 and bottomed at 0.01% in Q1 2026.
  • The 3-year median for Return on Assets is 0.01% (2025), against an average of 0.01%.
  • Biggest YoY gain for Return on Assets was 1 bps in 2025; the steepest drop was 1 bps in 2025.
  • Year by year, Return on Assets stood at 0.0% in 2024, then tumbled by 149 bps to 0.01% in 2025, then slipped by 17 bps to 0.01% in 2026.
  • Per Business Quant, the three latest UPB Return on Assets figures stand at 0.01% (Q1 2026), 0.01% (Q4 2025), and 0.01% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROA (Qtr)
1 Oculis Holding AG 66,079.99 Bn 66,079.71 Bn - -0.69%
2 Nanobiotix 1,912.79 Bn 1,912.73 Bn - -
3 Akari Therapeutics 1,022.34 Bn 1,022.34 Bn - -0.01%
4 BeOne Medicines 471.68 Bn 466.89 Bn 1.35 Bn 0.00%
5 Vertex Pharmaceuticals 122.31 Bn 115.06 Bn 2.59 Bn 0.00%
6 Regeneron Pharmaceuticals 70.24 Bn 61.49 Bn 3.31 Bn 0.00%
7 Belite Bio 63.01 Bn 63.01 Bn - -0.80%
8 Argenx Se 56.02 Bn 50.83 Bn 1.41 Bn -
9 Alnylam Pharmaceuticals 37.46 Bn 34.45 Bn 959.66 Mn 0.00%
10 Upstream Bio 350.44 Mn 350.44 Mn -3.94 Mn -0.01%

Historic Data

Download Data
DateValue
Mar 31, 2026 -0.01%
Dec 31, 2025 -0.01%
Sep 30, 2025 -0.01%
Jun 30, 2025 -0.01%
Mar 31, 2025 0.00%
Dec 31, 2024 0.00%