Upstream Bio (UPB) Return on Assets (2024 - 2026)
Upstream Bio's (UPB) quarterly Return on Assets came in at 0.01% in Q1 2026, down 1.0% year-on-year from 0.01% in Q1 2025, and down 17.42% quarter-over-quarter from 0.01% in Q4 2025.
Upstream Bio (UPB) Return on Assets (2024 - 2026) Analysis & Trends
Upstream Bio's Return on Assets history runs 3 years deep, the most recent figure standing at 0.01% for Q1 2026.
- On a quarterly basis, Return on Assets fell 1.0% year-over-year to 0.01% in Q1 2026; TTM through Mar 2026 was 0.01%, a 1.0% decrease from a year earlier, with the FY2025 full-year figure at 0.01%, changed 0.0% from the prior year.
- Return on Assets declined to 0.01% in Q1 2026 per UPB's latest filing, from 0.01% in the prior quarter.
- Across five years, Return on Assets topped out at 0.0% in Q1 2025 and bottomed at 0.01% in Q1 2026.
- The 3-year median for Return on Assets is 0.01% (2025), against an average of 0.01%.
- Biggest YoY gain for Return on Assets was 1 bps in 2025; the steepest drop was 1 bps in 2025.
- Year by year, Return on Assets stood at 0.0% in 2024, then tumbled by 149 bps to 0.01% in 2025, then slipped by 17 bps to 0.01% in 2026.
- Per Business Quant, the three latest UPB Return on Assets figures stand at 0.01% (Q1 2026), 0.01% (Q4 2025), and 0.01% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROA (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 66,079.99 Bn | 66,079.71 Bn | - | -0.69% |
| 2 | Nanobiotix | 1,912.79 Bn | 1,912.73 Bn | - | - |
| 3 | Akari Therapeutics | 1,022.34 Bn | 1,022.34 Bn | - | -0.01% |
| 4 | BeOne Medicines | 471.68 Bn | 466.89 Bn | 1.35 Bn | 0.00% |
| 5 | Vertex Pharmaceuticals | 122.31 Bn | 115.06 Bn | 2.59 Bn | 0.00% |
| 6 | Regeneron Pharmaceuticals | 70.24 Bn | 61.49 Bn | 3.31 Bn | 0.00% |
| 7 | Belite Bio | 63.01 Bn | 63.01 Bn | - | -0.80% |
| 8 | Argenx Se | 56.02 Bn | 50.83 Bn | 1.41 Bn | - |
| 9 | Alnylam Pharmaceuticals | 37.46 Bn | 34.45 Bn | 959.66 Mn | 0.00% |
| 10 | Upstream Bio | 350.44 Mn | 350.44 Mn | -3.94 Mn | -0.01% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -0.01% |
| Dec 31, 2025 | -0.01% |
| Sep 30, 2025 | -0.01% |
| Jun 30, 2025 | -0.01% |
| Mar 31, 2025 | 0.00% |
| Dec 31, 2024 | 0.00% |