Upstream Bio (UPB) Change in Cash (2023 - 2026)

Upstream Bio's Change in Cash history runs 4 years deep, the most recent figure standing at -$4.9 million for Q1 2026.

• In Q1 2026, Change in Cash rose 98.09% year-over-year to -$4.9 million; the TTM figure through Mar 2026 stood at $25.4 million (down 36.46% YoY), while the FY2025 annual figure was -$224.3 million, down 174.71% from the prior year.
• Change in Cash for Q1 2026 stood at -$4.9 million, down from $29.4 million in the prior quarter.
• The five-year high for Change in Cash was $292.9 million in Q4 2024, with the low at -$254.6 million in Q1 2025.
• The 4-year median for Change in Cash is $411500.0 (2024), against an average of $5.0 million.
• The sharpest annual moves came in 2024 and 2025: Change in Cash surged 1463.48% in 2024, then slumped 4584.41% in 2025.
• Upstream Bio's Change in Cash stood at -$21.5 million in 2023, then soared by 1463.48% to $292.9 million in 2024, then sank by 89.96% to $29.4 million in 2025, then plunged by 116.5% to -$4.9 million in 2026.
• Business Quant data shows UPB's Change in Cash at -$4.9 million in Q1 2026, $29.4 million in Q4 2025, and $26.7 million in Q3 2025.