Upstream Bio (UPB) Share-based Compensation (2023 - 2026)

Upstream Bio's (UPB) quarterly Share-based Compensation came in at $43.4 million in Q1 2026, up 1547.06% year-on-year from $2.6 million in Q1 2025, and up 654.56% quarter-over-quarter from -$7.8 million in Q4 2025.

Upstream Bio (UPB) Share-based Compensation (2023 - 2026) Analysis & Trends

Upstream Bio's Share-based Compensation history runs 4 years deep, the most recent figure standing at $43.4 million for Q1 2026.

  • On a quarterly basis, Share-based Compensation rose 1547.06% year-over-year to $43.4 million in Q1 2026; TTM through Mar 2026 was $43.4 million, a 442.77% increase from a year earlier, with the FY2025 full-year figure at $21.4 million, up 37.18% from the prior year.
  • Share-based Compensation grew to $43.4 million in Q1 2026 per UPB's latest filing, from -$7.8 million in the prior quarter.
  • Across five years, Share-based Compensation topped out at $43.4 million in Q1 2026 and bottomed at -$7.8 million in Q4 2025.
  • The 4-year median for Share-based Compensation is $1.9 million (2024), against an average of $8.5 million.
  • Biggest YoY gain for Share-based Compensation was 1628.05% in 2025; the steepest drop was 475.17% in 2025.
  • Year by year, Share-based Compensation stood at $711000.0 in 2023, then jumped by 193.39% to $2.1 million in 2024, then tumbled by 475.17% to -$7.8 million in 2025, then jumped by 654.56% to $43.4 million in 2026.
  • Per Business Quant, the three latest UPB Share-based Compensation figures stand at $43.4 million (Q1 2026), -$7.8 million (Q4 2025), and $23.0 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Share-based Compensation (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - 6.39 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 3.20 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 9.26 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 166.40 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 257.40 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - 87.30 Mn
10 Upstream Bio 343.65 Mn 343.65 Mn -3.94 Mn 43.40 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 43.40 Mn
Mar 31, 2026 43.40 Mn
Dec 31, 2025 -7.83 Mn
Dec 31, 2025 -7.83 Mn
Sep 30, 2025 23.00 Mn
Sep 30, 2025 23.00 Mn
Jun 30, 2025 24.40 Mn
Jun 30, 2025 24.40 Mn
Mar 31, 2025 2.64 Mn
Mar 31, 2025 2.64 Mn
Dec 31, 2024 2.09 Mn
Dec 31, 2024 2.09 Mn
Sep 30, 2024 1.86 Mn
Sep 30, 2024 1.86 Mn
Jun 30, 2024 1.41 Mn
Jun 30, 2024 1.41 Mn
Mar 31, 2024 643,000.00
Mar 31, 2024 643,000.00
Dec 31, 2023 711,000.00
Dec 31, 2023 711,000.00