Upstream Bio (UPB) Share-based Compensation (2023 - 2026)
Upstream Bio's (UPB) quarterly Share-based Compensation came in at $43.4 million in Q1 2026, up 1547.06% year-on-year from $2.6 million in Q1 2025, and up 654.56% quarter-over-quarter from -$7.8 million in Q4 2025.
Upstream Bio (UPB) Share-based Compensation (2023 - 2026) Analysis & Trends
Upstream Bio's Share-based Compensation history runs 4 years deep, the most recent figure standing at $43.4 million for Q1 2026.
- On a quarterly basis, Share-based Compensation rose 1547.06% year-over-year to $43.4 million in Q1 2026; TTM through Mar 2026 was $43.4 million, a 442.77% increase from a year earlier, with the FY2025 full-year figure at $21.4 million, up 37.18% from the prior year.
- Share-based Compensation grew to $43.4 million in Q1 2026 per UPB's latest filing, from -$7.8 million in the prior quarter.
- Across five years, Share-based Compensation topped out at $43.4 million in Q1 2026 and bottomed at -$7.8 million in Q4 2025.
- The 4-year median for Share-based Compensation is $1.9 million (2024), against an average of $8.5 million.
- Biggest YoY gain for Share-based Compensation was 1628.05% in 2025; the steepest drop was 475.17% in 2025.
- Year by year, Share-based Compensation stood at $711000.0 in 2023, then jumped by 193.39% to $2.1 million in 2024, then tumbled by 475.17% to -$7.8 million in 2025, then jumped by 654.56% to $43.4 million in 2026.
- Per Business Quant, the three latest UPB Share-based Compensation figures stand at $43.4 million (Q1 2026), -$7.8 million (Q4 2025), and $23.0 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Share-based Compensation (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | 6.39 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 3.20 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 9.26 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 166.40 Mn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 257.40 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | - |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 87.30 Mn |
| 10 | Upstream Bio | 343.65 Mn | 343.65 Mn | -3.94 Mn | 43.40 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 43.40 Mn |
| Mar 31, 2026 | 43.40 Mn |
| Dec 31, 2025 | -7.83 Mn |
| Dec 31, 2025 | -7.83 Mn |
| Sep 30, 2025 | 23.00 Mn |
| Sep 30, 2025 | 23.00 Mn |
| Jun 30, 2025 | 24.40 Mn |
| Jun 30, 2025 | 24.40 Mn |
| Mar 31, 2025 | 2.64 Mn |
| Mar 31, 2025 | 2.64 Mn |
| Dec 31, 2024 | 2.09 Mn |
| Dec 31, 2024 | 2.09 Mn |
| Sep 30, 2024 | 1.86 Mn |
| Sep 30, 2024 | 1.86 Mn |
| Jun 30, 2024 | 1.41 Mn |
| Jun 30, 2024 | 1.41 Mn |
| Mar 31, 2024 | 643,000.00 |
| Mar 31, 2024 | 643,000.00 |
| Dec 31, 2023 | 711,000.00 |
| Dec 31, 2023 | 711,000.00 |