Upstream Bio (UPB) EBIT Margin (2023 - 2025)

Upstream Bio has reported EBIT Margin over the past 3 years, most recently at 6911.23% for Q4 2025.

  • Quarterly results put EBIT Margin at 6911.23% for Q4 2025, down 261792.0% from a year ago — trailing twelve months through Dec 2025 was 5618.82% (down 233763.0% YoY), and the annual figure for FY2025 was 5618.82%, down 233763.0%.
  • EBIT Margin for Q4 2025 was 6911.23% at Upstream Bio, down from 5539.39% in the prior quarter.
  • Over the last five years, EBIT Margin for UPB hit a ceiling of 1511.43% in Q3 2023 and a floor of 6911.23% in Q4 2025.
  • Median EBIT Margin over the past 3 years was 3866.26% (2024), compared with a mean of 4072.62%.
  • Biggest five-year swings in EBIT Margin: plummeted -110887bps in 2024 and later tumbled -331023bps in 2025.
  • Upstream Bio's EBIT Margin stood at 3184.44% in 2023, then crashed by -35bps to 4293.31% in 2024, then crashed by -61bps to 6911.23% in 2025.
  • The last three reported values for EBIT Margin were 6911.23% (Q4 2025), 5539.39% (Q3 2025), and 4732.87% (Q2 2025) per Business Quant data.