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Upstream Bio (UPB) Free Cash Flow: 2023-2025

Historic Free Cash Flow for Upstream Bio (UPB) over the last 2 years, with Sep 2025 value amounting to -$22.3 million.

  • Upstream Bio's Free Cash Flow fell 59.75% to -$22.3 million in Q3 2025 from the same period last year, while for Sep 2025 it was -$122.5 million, marking a year-over-year decrease of 120.06%. This contributed to the annual value of -$59.7 million for FY2024, which is 56.77% down from last year.
  • Latest data reveals that Upstream Bio reported Free Cash Flow of -$22.3 million as of Q3 2025, which was up 43.16% from -$39.2 million recorded in Q2 2025.
  • Upstream Bio's Free Cash Flow's 5-year high stood at -$8.0 million during Q2 2024, with a 5-year trough of -$41.2 million in Q1 2025.
  • In the last 3 years, Upstream Bio's Free Cash Flow had a median value of -$18.7 million in 2024 and averaged -$22.3 million.
  • Data for Upstream Bio's Free Cash Flow shows a maximum YoY tumbled of 388.29% (in 2025) over the last 5 years.
  • Upstream Bio's Free Cash Flow (Quarterly) stood at -$16.1 million in 2023, then dropped by 22.89% to -$19.8 million in 2024, then tumbled by 59.75% to -$22.3 million in 2025.
  • Its last three reported values are -$22.3 million in Q3 2025, -$39.2 million for Q2 2025, and -$41.2 million during Q1 2025.