Upstream Bio (UPB) Equity Average (2023 - 2025)

Upstream Bio has reported Equity Average over the past 3 years, most recently at $359.2 million for Q4 2025.

  • Quarterly results put Equity Average at $359.2 million for Q4 2025, up 132.07% from a year ago — trailing twelve months through Dec 2025 was $359.2 million (up 132.07% YoY), and the annual figure for FY2025 was $404.8 million, up 133.51%.
  • Equity Average for Q4 2025 was $359.2 million at Upstream Bio, down from $393.7 million in the prior quarter.
  • Over the last five years, Equity Average for UPB hit a ceiling of $457.7 million in Q1 2025 and a floor of -$153.5 million in Q3 2024.
  • Median Equity Average over the past 3 years was $154.8 million (2024), compared with a mean of $139.2 million.
  • Peak annual rise in Equity Average hit 456.86% in 2025, while the deepest fall reached 132.07% in 2025.
  • Upstream Bio's Equity Average stood at -$117.7 million in 2023, then surged by 231.53% to $154.8 million in 2024, then surged by 132.07% to $359.2 million in 2025.
  • The last three reported values for Equity Average were $359.2 million (Q4 2025), $393.7 million (Q3 2025), and $427.2 million (Q2 2025) per Business Quant data.