Upstream Bio (UPB) Income towards Parent Company (2023 - 2026)

Upstream Bio's (UPB) quarterly Income towards Parent Company came in at -$61.8 million in Q1 2026, down 77.23% year-on-year from -$271.3 million in Q1 2025, and up 69.83% quarter-over-quarter from -$204.8 million in Q4 2025.

Upstream Bio (UPB) Income towards Parent Company (2023 - 2026) Analysis & Trends

Upstream Bio's Income towards Parent Company history runs 4 years deep, the most recent figure standing at -$61.8 million for Q1 2026.

  • On a quarterly basis, Income towards Parent Company fell 77.23% year-over-year to -$61.8 million in Q1 2026; TTM through Mar 2026 was -$484.0 million, a 146.9% decrease from a year earlier, with the FY2025 full-year figure at -$305.7 million, down 123.29% from the prior year.
  • Income towards Parent Company improved to -$61.8 million in Q1 2026 per UPB's latest filing, from -$204.8 million in the prior quarter.
  • Across five years, Income towards Parent Company topped out at -$7.9 million in Q3 2023 and bottomed at -$204.8 million in Q4 2025.
  • The 4-year median for Income towards Parent Company is -$52.5 million (2023), against an average of -$68.7 million.
  • Biggest YoY gain for Income towards Parent Company was 76.19% in 2024; the steepest drop was 549.96% in 2024.
  • Year by year, Income towards Parent Company stood at -$52.5 million in 2023, then sank by 76.19% to -$92.5 million in 2024, then tumbled by 121.38% to -$204.8 million in 2025, then surged by 69.83% to -$61.8 million in 2026.
  • Per Business Quant, the three latest UPB Income towards Parent Company figures stand at -$61.8 million (Q1 2026), -$204.8 million (Q4 2025), and -$133.3 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn
7 Belite Bio 61.40 Bn 61.40 Bn -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn
9 Revolution Medicines 37.37 Bn 37.37 Bn -
10 Upstream Bio 343.65 Mn 343.65 Mn -3.94 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -61.79 Mn
Dec 31, 2025 -204.79 Mn
Sep 30, 2025 -133.27 Mn
Jun 30, 2025 -84.15 Mn
Mar 31, 2025 -34.86 Mn
Dec 31, 2024 -92.51 Mn
Sep 30, 2024 -51.08 Mn
Jun 30, 2024 -17.57 Mn
Mar 31, 2024 -15.06 Mn
Dec 31, 2023 -52.51 Mn
Sep 30, 2023 -7.86 Mn