Upstream Bio UPB
NASDAQ UPB
$6.01 -0.07 (-1.15%)
As of: Sep 4, 2026 · 3:59 PM EDT

Upstream Bio (UPB) Cash & Equivalents (2023 - 2026)

Upstream Bio (UPB) posted quarterly Cash & Equivalents of $96.7 million for Q1 2026, up 35.63% year-over-year from $71.3 million in Q1 2025, and down 4.78% quarter-over-quarter from $101.6 million in Q4 2025.

Analysis

Upstream Bio (UPB) Cash & Equivalents (2023 - 2026) Analysis & Trends

Upstream Bio's Cash & Equivalents history runs 4 years deep, the most recent figure standing at $96.7 million for Q1 2026.

  • In Q1 2026, Cash & Equivalents rose 35.63% year-over-year to $96.7 million; the TTM figure through Mar 2026 stood at $96.7 million (up 35.63% YoY), while the FY2025 annual figure was $101.6 million, down 68.83% from the prior year.
  • Cash & Equivalents for Q1 2026 stood at $96.7 million, down from $101.6 million in the prior quarter.
  • The five-year high for Cash & Equivalents was $325.9 million in Q4 2024, with the low at $25.8 million in Q4 2023.
  • The 4-year median for Cash & Equivalents is $47.3 million (2024), against an average of $81.6 million.
  • The sharpest annual moves came in 2024 and 2025: Cash & Equivalents surged 1161.53% in 2024, then slumped 68.83% in 2025.
  • Upstream Bio's Cash & Equivalents stood at $25.8 million in 2023, then soared by 1161.53% to $325.9 million in 2024, then plunged by 68.83% to $101.6 million in 2025, then fell by 4.78% to $96.7 million in 2026.
  • Business Quant data shows UPB's Cash & Equivalents at $96.7 million in Q1 2026, $101.6 million in Q4 2025, and $72.2 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Equiv. (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 6.14 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 2.46 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 3.58 Bn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn 1.72 Bn
5 Revolution Medicines 44.33 Bn 44.33 Bn - 815.44 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 5.10 Bn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 1.71 Bn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 811.99 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn 544.80 Mn
10 Upstream Bio 327.95 Mn 327.95 Mn -3.29 Mn 79.40 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 79.40 Mn
Mar 31, 2026 96.72 Mn
Dec 31, 2025 101.58 Mn
Sep 30, 2025 72.16 Mn
Jun 30, 2025 45.46 Mn
Mar 31, 2025 71.31 Mn
Dec 31, 2024 325.89 Mn
Sep 30, 2024 32.95 Mn
Jun 30, 2024 47.34 Mn
Mar 31, 2024 31.51 Mn
Dec 31, 2023 25.83 Mn
Sep 30, 2023 47.32 Mn