Upstream Bio (UPB) Cash & Equivalents (2023 - 2026)

Upstream Bio's quarterly Cash & Equivalents came in at $96.7 million in Q1 2026, up 35.63% year-on-year from $71.3 million in Q1 2025, and down 4.78% quarter-over-quarter from $101.6 million in Q4 2025.

Upstream Bio has reported Cash & Equivalents for 4 years, with the latest figure at $96.7 million in Q1 2026.

  • For the quarter ending Q1 2026, Cash & Equivalents rose 35.63% year-over-year to $96.7 million; the trailing twelve-month figure through Mar 2026 stood at $96.7 million (up 35.63% YoY), and the FY2025 full-year result was $101.6 million, down 68.36% from the prior year.
  • Cash & Equivalents for Q1 2026 stood at $96.7 million, down from $101.6 million in the prior quarter.
  • The five-year high for Cash & Equivalents was $321.0 million in Q4 2024, with the low at $25.8 million in Q4 2023.
  • Average Cash & Equivalents over 4 years is $81.2 million, with a median of $47.3 million recorded in 2024.
  • Year-over-year, Cash & Equivalents soared 1142.6% in 2024 and slumped 68.36% in 2025.
  • Tracing UPB's Cash & Equivalents over 4 years: stood at $25.8 million in 2023, then soared by 1142.6% to $321.0 million in 2024, then tumbled by 68.36% to $101.6 million in 2025, then decreased by 4.78% to $96.7 million in 2026.
  • The last three Cash & Equivalents figures came in at $96.7 million (Q1 2026), $101.6 million (Q4 2025), and $72.2 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Equiv. (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - 1.91 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - 32.30 Mn
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn 286.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - 61.46 Mn
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - 2.77 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 5.49 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - 18.44 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 2.96 Bn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 1.71 Bn
10 Upstream Bio 454.22 Mn 454.22 Mn -3.94 Mn 96.72 Mn

Historic Data

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DateValue
Mar 31, 2026 96.72 Mn
Dec 31, 2025 101.58 Mn
Sep 30, 2025 72.16 Mn
Jun 30, 2025 45.46 Mn
Mar 31, 2025 71.31 Mn
Dec 31, 2024 321.00 Mn
Sep 30, 2024 32.95 Mn
Jun 30, 2024 47.34 Mn
Mar 31, 2024 31.51 Mn
Dec 31, 2023 25.83 Mn
Sep 30, 2023 47.32 Mn