Upstream Bio (UPB) Cash & Equivalents (2023 - 2026)

Upstream Bio's (UPB) quarterly Cash & Equivalents came in at $96.7 million in Q1 2026, up 35.63% year-on-year from $71.3 million in Q1 2025, and down 4.78% quarter-over-quarter from $101.6 million in Q4 2025.

Upstream Bio (UPB) Cash & Equivalents (2023 - 2026) Analysis & Trends

Upstream Bio's Cash & Equivalents history runs 4 years deep, the most recent figure standing at $96.7 million for Q1 2026.

  • On a quarterly basis, Cash & Equivalents rose 35.63% year-over-year to $96.7 million in Q1 2026; TTM through Mar 2026 was $96.7 million, a 35.63% increase from a year earlier, with the FY2025 full-year figure at $101.6 million, down 68.83% from the prior year.
  • Cash & Equivalents slipped to $96.7 million in Q1 2026 per UPB's latest filing, from $101.6 million in the prior quarter.
  • Across five years, Cash & Equivalents topped out at $325.9 million in Q4 2024 and bottomed at $25.8 million in Q4 2023.
  • The 4-year median for Cash & Equivalents is $47.3 million (2024), against an average of $81.6 million.
  • Across the five-year window, Cash & Equivalents surged 1161.53% in 2024 and tumbled 68.83% in 2025, its largest moves.
  • Year by year, Cash & Equivalents stood at $25.8 million in 2023, then jumped by 1161.53% to $325.9 million in 2024, then tumbled by 68.83% to $101.6 million in 2025, then retreated by 4.78% to $96.7 million in 2026.
  • Per Business Quant, the three latest UPB Cash & Equivalents figures stand at $96.7 million (Q1 2026), $101.6 million (Q4 2025), and $72.2 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Equiv. (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - 82.45 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - 61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - 32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 5.49 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 3.58 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 440.94 Mn
10 Upstream Bio 347.73 Mn 347.73 Mn -3.94 Mn 96.72 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 96.72 Mn
Dec 31, 2025 101.58 Mn
Sep 30, 2025 72.16 Mn
Jun 30, 2025 45.46 Mn
Mar 31, 2025 71.31 Mn
Dec 31, 2024 325.89 Mn
Sep 30, 2024 32.95 Mn
Jun 30, 2024 47.34 Mn
Mar 31, 2024 31.51 Mn
Dec 31, 2023 25.83 Mn
Sep 30, 2023 47.32 Mn