Upstream Bio (UPB) Cash & Equivalents (2023 - 2026)

Upstream Bio (UPB) recorded quarterly Cash & Equivalents of $96.7 million in Q1 2026, down 4.78% quarter-over-quarter from $101.6 million in Q4 2025, and up 35.63% on a YoY basis from $71.3 million in Q1 2025.

Upstream Bio (UPB) Cash & Equivalents (2023 - 2026) Analysis & Trends

Upstream Bio's Cash & Equivalents history runs 4 years deep, the most recent figure standing at $96.7 million for Q1 2026.

  • In Q1 2026, Cash & Equivalents rose 35.63% year-over-year to $96.7 million; the TTM figure through Mar 2026 stood at $96.7 million (up 35.63% YoY), while the FY2025 annual figure was $101.6 million, down 68.36% from the prior year.
  • Cash & Equivalents was $96.7 million for Q1 2026 at Upstream Bio, down from $101.6 million in the prior quarter.
  • In the past five years, Cash & Equivalents ranged from a high of $321.0 million in Q4 2024 to a low of $25.8 million in Q4 2023.
  • Historically, Cash & Equivalents has averaged $81.2 million across 4 years, with a median of $47.3 million in 2024.
  • The sharpest annual moves came in 2024 and 2025: Cash & Equivalents jumped 1142.6% in 2024, then slumped 68.36% in 2025.
  • A 4-year view of Cash & Equivalents shows it stood at $25.8 million in 2023, then surged by 1142.6% to $321.0 million in 2024, then plunged by 68.36% to $101.6 million in 2025, then retreated by 4.78% to $96.7 million in 2026.
  • The last three Cash & Equivalents figures came in at $96.7 million (Q1 2026), $101.6 million (Q4 2025), and $72.2 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Equiv. (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 1.91 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 7.15 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 5.49 Bn
9 Abivax 91.96 Bn 91.96 Bn - 558.94 Mn
10 Upstream Bio 339.03 Mn 339.03 Mn -3.94 Mn 96.72 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 96.72 Mn
Dec 31, 2025 101.58 Mn
Sep 30, 2025 72.16 Mn
Jun 30, 2025 45.46 Mn
Mar 31, 2025 71.31 Mn
Dec 31, 2024 321.00 Mn
Sep 30, 2024 32.95 Mn
Jun 30, 2024 47.34 Mn
Mar 31, 2024 31.51 Mn
Dec 31, 2023 25.83 Mn
Sep 30, 2023 47.32 Mn