Upstream Bio (UPB) Common Equity (2023 - 2026)
Upstream Bio (UPB) posted quarterly Common Equity of $304.0 million for Q1 2026, down 31.78% year-over-year from $445.6 million in Q1 2025, and down 10.53% quarter-over-quarter from $339.8 million in Q4 2025.
Analysis
Upstream Bio (UPB) Common Equity (2023 - 2026) Analysis & Trends
Upstream Bio's Common Equity history runs 4 years deep, the most recent figure standing at $304.0 million for Q1 2026.
- In Q1 2026, Common Equity fell 31.78% year-over-year to $304.0 million; the TTM figure through Mar 2026 stood at $304.0 million (down 31.78% YoY), while the FY2025 annual figure was $339.8 million, down 27.69% from the prior year.
- Common Equity for Q1 2026 stood at $304.0 million, down from $339.8 million in the prior quarter.
- The five-year high for Common Equity was $469.9 million in Q4 2024, with the low at -$160.3 million in Q3 2024.
- The 4-year median for Common Equity is $304.0 million (2026), against an average of $151.9 million.
- Peak annual rise in Common Equity reached 481.6% in 2024, while the deepest fall reached 42.87% in 2024.
- Upstream Bio's Common Equity stood at -$123.1 million in 2023, then soared by 481.6% to $469.9 million in 2024, then slipped by 27.69% to $339.8 million in 2025, then slipped by 10.53% to $304.0 million in 2026.
- Business Quant data shows UPB's Common Equity at $304.0 million in Q1 2026, $339.8 million in Q4 2025, and $378.6 million in Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Common Equity (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 20.25 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 31.71 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 8.42 Bn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | 6.76 Bn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | 2.61 Bn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 5.17 Bn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 1.35 Bn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 9.79 Bn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | 757.49 Mn |
| 10 | Upstream Bio | 327.95 Mn | 327.95 Mn | -3.29 Mn | 270.96 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 270.96 Mn |
| Mar 31, 2026 | 304.00 Mn |
| Dec 31, 2025 | 339.77 Mn |
| Sep 30, 2025 | 378.58 Mn |
| Jun 30, 2025 | 408.74 Mn |
| Mar 31, 2025 | 445.61 Mn |
| Dec 31, 2024 | 469.85 Mn |
| Sep 30, 2024 | -160.31 Mn |
| Jun 30, 2024 | -146.61 Mn |
| Mar 31, 2024 | -133.41 Mn |
| Dec 31, 2023 | -123.13 Mn |
| Sep 30, 2023 | -112.20 Mn |