Upstream Bio (UPB) Common Equity (2023 - 2026)
Upstream Bio's quarterly Common Equity came in at $304.0 million in Q1 2026, down 31.78% year-on-year from $445.6 million in Q1 2025, and down 10.53% quarter-over-quarter from $339.8 million in Q4 2025.
Upstream Bio has reported Common Equity for 4 years, with the latest figure at $304.0 million in Q1 2026.
- For the quarter ending Q1 2026, Common Equity fell 31.78% year-over-year to $304.0 million; the trailing twelve-month figure through Mar 2026 stood at $304.0 million (down 31.78% YoY), and the FY2025 full-year result was $339.8 million, down 27.69% from the prior year.
- Common Equity for Q1 2026 stood at $304.0 million, down from $339.8 million in the prior quarter.
- The five-year high for Common Equity was $469.9 million in Q4 2024, with the low at -$160.3 million in Q3 2024.
- Average Common Equity over 4 years is $151.9 million, with a median of $304.0 million recorded in 2026.
- Peak annual rise in Common Equity reached 481.6% in 2024, while the deepest fall reached 42.87% in 2024.
- Tracing UPB's Common Equity over 4 years: stood at -$123.1 million in 2023, then surged by 481.6% to $469.9 million in 2024, then declined by 27.69% to $339.8 million in 2025, then declined by 10.53% to $304.0 million in 2026.
- The last three Common Equity figures came in at $304.0 million (Q1 2026), $339.8 million (Q4 2025), and $378.6 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Common Equity (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | -1.42 Mn |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | 35.63 Mn |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | 1.00 Bn |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | 14.38 Mn |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 19.36 Bn |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | 13.21 Mn |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | 31.42 Bn |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 1.08 Bn |
| 10 | Upstream Bio | 454.22 Mn | 454.22 Mn | -3.94 Mn | 304.00 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 304.00 Mn |
| Dec 31, 2025 | 339.77 Mn |
| Sep 30, 2025 | 378.58 Mn |
| Jun 30, 2025 | 408.74 Mn |
| Mar 31, 2025 | 445.61 Mn |
| Dec 31, 2024 | 469.85 Mn |
| Sep 30, 2024 | -160.31 Mn |
| Jun 30, 2024 | -146.61 Mn |
| Mar 31, 2024 | -133.41 Mn |
| Dec 31, 2023 | -123.13 Mn |
| Sep 30, 2023 | -112.20 Mn |