Upstream Bio (UPB) Shares Issued (2023 - 2026)

Upstream Bio's (UPB) quarterly Shares Issued came in at $9.0 million in Q1 2026, up 310.48% year-on-year from $2.2 million in Q1 2025, and up 13.07% quarter-over-quarter from $8.0 million in Q4 2025.

Upstream Bio (UPB) Shares Issued (2023 - 2026) Analysis & Trends

Upstream Bio's Shares Issued history runs 4 years deep, the most recent figure standing at $9.0 million for Q1 2026.

  • On a quarterly basis, Shares Issued rose 310.48% year-over-year to $9.0 million in Q1 2026; TTM through Mar 2026 was $9.0 million, a 310.48% increase from a year earlier, with the FY2025 full-year figure at $8.0 million, up 22.65% from the prior year.
  • Shares Issued rose to $9.0 million in Q1 2026 per UPB's latest filing, from $8.0 million in the prior quarter.
  • Across five years, Shares Issued topped out at $9.0 million in Q1 2026 and bottomed at $1.9 million in Q3 2024.
  • The 4-year median for Shares Issued is $7.2 million (2024), against an average of $6.0 million.
  • Biggest YoY gain for Shares Issued was 337.15% in 2025; the steepest drop was 22.65% in 2025.
  • Year by year, Shares Issued stood at $4.2 million in 2023, then jumped by 55.79% to $6.5 million in 2024, then rose by 22.65% to $8.0 million in 2025, then rose by 13.07% to $9.0 million in 2026.
  • Per Business Quant, the three latest UPB Shares Issued figures stand at $9.0 million (Q1 2026), $8.0 million (Q4 2025), and $8.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Shares Issued (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - 19.44 Mn
10 Upstream Bio 347.73 Mn 347.73 Mn -3.94 Mn 9.00 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 9.00 Mn
Mar 31, 2026 9.00 Mn
Dec 31, 2025 7.96 Mn
Dec 31, 2025 7.96 Mn
Sep 30, 2025 8.14 Mn
Sep 30, 2025 8.14 Mn
Jun 30, 2025 8.25 Mn
Jun 30, 2025 8.25 Mn
Mar 31, 2025 2.19 Mn
Mar 31, 2025 2.19 Mn
Dec 31, 2024 6.49 Mn
Dec 31, 2024 6.49 Mn
Sep 30, 2024 1.86 Mn
Sep 30, 2024 1.86 Mn
Dec 31, 2023 4.17 Mn
Dec 31, 2023 4.17 Mn