Upstream Bio (UPB) Shares Issued (2023 - 2026)
Upstream Bio (UPB) posted quarterly Shares Issued of $9.0 million for Q1 2026, up 310.48% year-over-year from $2.2 million in Q1 2025, and up 13.07% quarter-over-quarter from $8.0 million in Q4 2025.
Upstream Bio (UPB) Shares Issued (2023 - 2026) Analysis & Trends
Upstream Bio's Shares Issued history runs 4 years deep, the most recent figure standing at $9.0 million for Q1 2026.
- In Q1 2026, Shares Issued rose 310.48% year-over-year to $9.0 million; the TTM figure through Mar 2026 stood at $9.0 million (up 310.48% YoY), while the FY2025 annual figure was $8.0 million, up 22.65% from the prior year.
- Shares Issued for Q1 2026 stood at $9.0 million, up from $8.0 million in the prior quarter.
- The five-year high for Shares Issued was $9.0 million in Q1 2026, with the low at $1.9 million in Q3 2024.
- The 4-year median for Shares Issued is $7.2 million (2024), against an average of $6.0 million.
- Peak annual rise in Shares Issued reached 337.15% in 2025, while the deepest fall reached 22.65% in 2025.
- Upstream Bio's Shares Issued stood at $4.2 million in 2023, then soared by 55.79% to $6.5 million in 2024, then increased by 22.65% to $8.0 million in 2025, then increased by 13.07% to $9.0 million in 2026.
- Business Quant data shows UPB's Shares Issued at $9.0 million in Q1 2026, $8.0 million in Q4 2025, and $8.1 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Shares Issued (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | - |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | - |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | - |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 18.36 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | - |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | - |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | - |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | - |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | - |
| 10 | Upstream Bio | 387.23 Mn | 387.23 Mn | -3.29 Mn | 9.29 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 9.29 Mn |
| Jun 30, 2026 | 9.29 Mn |
| Mar 31, 2026 | 9.00 Mn |
| Mar 31, 2026 | 9.00 Mn |
| Dec 31, 2025 | 7.96 Mn |
| Dec 31, 2025 | 7.96 Mn |
| Sep 30, 2025 | 8.14 Mn |
| Sep 30, 2025 | 8.14 Mn |
| Jun 30, 2025 | 8.25 Mn |
| Jun 30, 2025 | 8.25 Mn |
| Mar 31, 2025 | 2.19 Mn |
| Mar 31, 2025 | 2.19 Mn |
| Dec 31, 2024 | 6.49 Mn |
| Dec 31, 2024 | 6.49 Mn |
| Sep 30, 2024 | 1.86 Mn |
| Sep 30, 2024 | 1.86 Mn |
| Dec 31, 2023 | 4.17 Mn |
| Dec 31, 2023 | 4.17 Mn |