Upstream Bio (UPB) Shares Issued (2023 - 2026)
Upstream Bio's (UPB) quarterly Shares Issued came in at $9.0 million in Q1 2026, up 310.48% year-on-year from $2.2 million in Q1 2025, and up 13.07% quarter-over-quarter from $8.0 million in Q4 2025.
Upstream Bio (UPB) Shares Issued (2023 - 2026) Analysis & Trends
Upstream Bio's Shares Issued history runs 4 years deep, the most recent figure standing at $9.0 million for Q1 2026.
- On a quarterly basis, Shares Issued rose 310.48% year-over-year to $9.0 million in Q1 2026; TTM through Mar 2026 was $9.0 million, a 310.48% increase from a year earlier, with the FY2025 full-year figure at $8.0 million, up 22.65% from the prior year.
- Shares Issued rose to $9.0 million in Q1 2026 per UPB's latest filing, from $8.0 million in the prior quarter.
- Across five years, Shares Issued topped out at $9.0 million in Q1 2026 and bottomed at $1.9 million in Q3 2024.
- The 4-year median for Shares Issued is $7.2 million (2024), against an average of $6.0 million.
- Biggest YoY gain for Shares Issued was 337.15% in 2025; the steepest drop was 22.65% in 2025.
- Year by year, Shares Issued stood at $4.2 million in 2023, then jumped by 55.79% to $6.5 million in 2024, then rose by 22.65% to $8.0 million in 2025, then rose by 13.07% to $9.0 million in 2026.
- Per Business Quant, the three latest UPB Shares Issued figures stand at $9.0 million (Q1 2026), $8.0 million (Q4 2025), and $8.1 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Shares Issued (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | - |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | - |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | - |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | 19.44 Mn |
| 10 | Upstream Bio | 347.73 Mn | 347.73 Mn | -3.94 Mn | 9.00 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 9.00 Mn |
| Mar 31, 2026 | 9.00 Mn |
| Dec 31, 2025 | 7.96 Mn |
| Dec 31, 2025 | 7.96 Mn |
| Sep 30, 2025 | 8.14 Mn |
| Sep 30, 2025 | 8.14 Mn |
| Jun 30, 2025 | 8.25 Mn |
| Jun 30, 2025 | 8.25 Mn |
| Mar 31, 2025 | 2.19 Mn |
| Mar 31, 2025 | 2.19 Mn |
| Dec 31, 2024 | 6.49 Mn |
| Dec 31, 2024 | 6.49 Mn |
| Sep 30, 2024 | 1.86 Mn |
| Sep 30, 2024 | 1.86 Mn |
| Dec 31, 2023 | 4.17 Mn |
| Dec 31, 2023 | 4.17 Mn |