Upstream Bio (UPB) Shares Issued (2024 - 2026)

Upstream Bio (UPB) recorded quarterly Shares Issued of $598000.0 in Q1 2026, up 150.85% quarter-over-quarter from -$1.2 million in Q4 2025.

Upstream Bio (UPB) Shares Issued (2024 - 2026) Analysis & Trends

Upstream Bio's Shares Issued history runs 3 years deep, the most recent figure standing at $598000.0 for Q1 2026.

  • In Q1 2026, Shares Issued changed N/A year-over-year to $598000.0; the TTM figure through Mar 2026 stood at $794000.0 (down 99.71% YoY), while the FY2025 annual figure was $196000.0, down 99.93% from the prior year.
  • Shares Issued was $598000.0 for Q1 2026 at Upstream Bio, up from -$1.2 million in the prior quarter.
  • In the past five years, Shares Issued ranged from a high of $272.6 million in Q4 2024 to a low of -$1.2 million in Q4 2025.
  • Historically, Shares Issued has averaged $34.2 million across 3 years, with a median of $349000.0 in 2024.
  • Biggest YoY gain for Shares Issued was 3900.0% in 2025; the steepest drop was 100.43% in 2025.
  • A 3-year view of Shares Issued shows it stood at $272.6 million in 2024, then slumped by 100.43% to -$1.2 million in 2025, then surged by 150.85% to $598000.0 in 2026.
  • The last three Shares Issued figures came in at $598000.0 (Q1 2026), -$1.2 million (Q4 2025), and $760000.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Shares Issued (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 5.40 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 27.00 Mn
9 Abivax 91.96 Bn 91.96 Bn - 26,927.15
10 Upstream Bio 339.03 Mn 339.03 Mn -3.94 Mn 598,000.00

Historic Data

Download Data
DateValue
Mar 31, 2026 598,000.00
Mar 31, 2026 598,000.00
Dec 31, 2025 -1.18 Mn
Dec 31, 2025 -1.18 Mn
Sep 30, 2025 760,000.00
Sep 30, 2025 760,000.00
Jun 30, 2025 612,000.00
Jun 30, 2025 612,000.00
Dec 31, 2024 272.59 Mn
Dec 31, 2024 272.59 Mn
Sep 30, 2024 19,000.00
Sep 30, 2024 19,000.00
Jun 30, 2024 100,000.00
Jun 30, 2024 100,000.00
Mar 31, 2024 12,000.00
Mar 31, 2024 12,000.00