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Upstream Bio (UPB) Net Cash Flow (2023 - 2025)

Upstream Bio (UPB) has 3 years of Net Cash Flow data on record, last reported at $26.7 million in Q3 2025.

  • For Q3 2025, Net Cash Flow rose 288.15% year-over-year to $26.7 million; the TTM value through Sep 2025 reached $39.2 million, up 376.64%, while the annual FY2024 figure was $300.3 million, 3318.96% up from the prior year.
  • Net Cash Flow reached $26.7 million in Q3 2025 per UPB's latest filing, up from -$25.9 million in the prior quarter.
  • Across five years, Net Cash Flow topped out at $292.9 million in Q4 2024 and bottomed at -$254.6 million in Q1 2025.
  • Average Net Cash Flow over 3 years is $3.1 million, with a median of -$4.3 million recorded in 2024.
  • Peak YoY movement for Net Cash Flow: soared 1463.48% in 2024, then plummeted 4584.41% in 2025.
  • A 3-year view of Net Cash Flow shows it stood at -$21.5 million in 2023, then skyrocketed by 1463.48% to $292.9 million in 2024, then crashed by 90.88% to $26.7 million in 2025.
  • Per Business Quant database, its latest 3 readings for Net Cash Flow were $26.7 million in Q3 2025, -$25.9 million in Q2 2025, and -$254.6 million in Q1 2025.