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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Sales

Upstream Bio (UPB) EBITDA Margin (2023 - 2025)

Historic EBITDA Margin for Upstream Bio (UPB) over the last 3 years, with Q3 2025 value amounting to 5539.39%.

  • Upstream Bio's EBITDA Margin fell 24268600.0% to 5539.39% in Q3 2025 from the same period last year, while for Sep 2025 it was 5020.08%, marking a year-over-year decrease of 20397400.0%. This contributed to the annual value of 3281.18% for FY2024, which is 15957200.0% down from last year.
  • According to the latest figures from Q3 2025, Upstream Bio's EBITDA Margin is 5539.39%, which was down 24268600.0% from 4732.87% recorded in Q2 2025.
  • Over the past 5 years, Upstream Bio's EBITDA Margin peaked at 1511.43% during Q3 2023, and registered a low of 5656.01% during Q1 2025.
  • Its 3-year average for EBITDA Margin is 3757.22%, with a median of 3439.22% in 2024.
  • Its EBITDA Margin has fluctuated over the past 5 years, first tumbled by -11088700bps in 2024, then plummeted by -33102300bps in 2025.
  • Upstream Bio's EBITDA Margin (Quarter) stood at 3184.44% in 2023, then tumbled by -35bps to 4293.31% in 2024, then dropped by -29bps to 5539.39% in 2025.
  • Its EBITDA Margin stands at 5539.39% for Q3 2025, versus 4732.87% for Q2 2025 and 5656.01% for Q1 2025.