Spyre Therapeutics (SYRE) Equity Ratio (2015 - 2026)
Spyre Therapeutics posted quarterly Equity Ratio of 0.88 for Q1 2026, up 3.67% year-on-year from 0.85 in Q1 2025, and down 4.51% on a QoQ basis from 0.92 in Q4 2025.
Spyre Therapeutics (SYRE) has 12 years of Equity Ratio data on file, last reported at 0.88 in Q1 2026.
- For the quarter ending Q1 2026, Equity Ratio rose 3.67% year-over-year to 0.88; the trailing twelve-month figure through Mar 2026 stood at 0.88 (up 3.67% YoY), and the FY2025 full-year result was 0.92, up 8.06% from the prior year.
- Equity Ratio for Q1 2026 stood at 0.88, down from 0.92 in the prior quarter.
- Across five years, Equity Ratio topped out at 0.92 in Q4 2025 and bottomed at 1.18 in Q3 2023.
- The 5-year median for Equity Ratio is 0.78 (2024), against an average of 0.55.
- The widest annual swing landed in 2023, when Equity Ratio slumped 260.48%; it then soared 200.83% in 2024.
- A 5-year view of Equity Ratio shows it stood at 0.71 in 2022, then slipped by 23.87% to 0.54 in 2023, then soared by 58.09% to 0.85 in 2024, then gained by 8.06% to 0.92 in 2025, then fell by 4.51% to 0.88 in 2026.
- The last three Equity Ratio figures came in at 0.88 (Q1 2026), 0.92 (Q4 2025), and 0.9 (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Equity Ratio (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 0.04 |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | - |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 0.42 |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 0.73 |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 0.77 |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 0.21 |
| 10 | Spyre Therapeutics | 5.55 Bn | 5.55 Bn | - | 0.88 |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 0.88 |
| Dec 31, 2025 | 0.92 |
| Sep 30, 2025 | 0.90 |
| Jun 30, 2025 | 0.85 |
| Mar 31, 2025 | 0.85 |
| Dec 31, 2024 | 0.85 |
| Sep 30, 2024 | 0.78 |
| Jun 30, 2024 | 0.86 |
| Mar 31, 2024 | 0.31 |
| Dec 31, 2023 | 0.54 |
| Sep 30, 2023 | -1.18 |
| Jun 30, 2023 | -0.85 |
| Mar 31, 2023 | 0.64 |
| Dec 31, 2022 | 0.71 |
| Sep 30, 2022 | 0.74 |
| Jun 30, 2022 | 0.79 |
| Mar 31, 2022 | 0.74 |
| Dec 31, 2021 | 0.76 |
| Sep 30, 2021 | 0.79 |
| Jun 30, 2021 | 0.81 |
| Mar 31, 2021 | 0.76 |
| Dec 31, 2020 | 0.87 |
| Sep 30, 2020 | 0.88 |
| Jun 30, 2020 | 0.88 |
| Mar 31, 2020 | 0.66 |
| Dec 31, 2019 | 0.72 |
| Sep 30, 2019 | 0.80 |
| Jun 30, 2019 | 0.85 |
| Mar 31, 2019 | 0.90 |
| Dec 31, 2018 | 0.87 |
| Sep 30, 2018 | 0.89 |
| Jun 30, 2018 | 0.92 |
| Mar 31, 2018 | 0.88 |
| Dec 31, 2017 | 0.90 |
| Sep 30, 2017 | 0.92 |
| Jun 30, 2017 | 0.93 |
| Mar 31, 2017 | 0.93 |
| Dec 31, 2016 | 0.94 |
| Sep 30, 2016 | 0.95 |
| Jun 30, 2016 | 0.96 |
| Mar 31, 2016 | -0.75 |
| Dec 31, 2015 | -0.57 |