Spyre Therapeutics SYRE
NASDAQ SYRE
$89.03 +4.31 (+5.09%)
At close: Sep 30, 2026 · 4:00 PM EDT

Spyre Therapeutics (SYRE) FCF Margin (2017 - 2023)

Updated

Spyre Therapeutics' FCF Margin came in at -11276.52% for FY2023, down 7833.76 percentage points from -3442.77% in FY2022.

Analysis

Spyre Therapeutics (SYRE) FCF Margin (2017 - 2023) Analysis & Trends

Going back to FY2016, Spyre Therapeutics' FCF Margin data covers 6 years.

  • FCF Margin carries a five-year change of -10440.24 percentage points (FY2018 to FY2023).
  • The FY2023 figure represents the lowest annual FCF Margin in data going back to FY2016.
  • Per Business Quant, earlier years put FCF Margin at -3442.77% in FY2022 (-3153.05 pp) and -289.71% in FY2021.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Johnson & Johnson 645.01 Bn 563.54 Bn 17.26 Bn 28.82%
2 AbbVie 465.23 Bn 438.39 Bn 12.70 Bn 18.33%
3 Merck 368.40 Bn 322.83 Bn 12.21 Bn 26.96%
4 Novartis Ag 278.02 Bn 233.89 Bn 11.24 Bn 43.05%
5 Astrazeneca 254.57 Bn 228.13 Bn 12.86 Bn 34.72%
6 Amgen 229.02 Bn 184.42 Bn 7.24 Bn 34.70%
7 Gilead Sciences 187.74 Bn 161.85 Bn 6.22 Bn 44.00%
8 Pfizer 163.75 Bn 110.70 Bn 10.94 Bn 2.01%
9 Vertex Pharmaceuticals 133.45 Bn 105.45 Bn 2.84 Bn 30.39%
10 Spyre Therapeutics 7.46 Bn 7.46 Bn - -
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2023 -2,419.04%
Mar 31, 2023 -8,906.06%
Dec 31, 2022 -10,797.62%
Sep 30, 2022 -8,660.34%
Jun 30, 2022 -3,307.68%
Mar 31, 2022 -1,930.98%
Dec 31, 2021 -528.76%
Sep 30, 2021 -1,221.80%
Jun 30, 2021 14.98%
Jun 30, 2018 -381.79%
Mar 31, 2018 -498.68%
Dec 31, 2017 -408.90%
Sep 30, 2017 -593.10%
Jun 30, 2017 -404.87%
Mar 31, 2017 -580.75%
API Access

Spyre Therapeutics FCF Margin API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=fcf-margin&ticker=SYRE&period=max&api_key=YOUR_API_KEY