Spyre Therapeutics (SYRE) Total Liabilities (2015 - 2026)

Spyre Therapeutics (SYRE) posted Total Liabilities of $93.1 million for Q1 2026, up 48.92% on a QoQ basis from $62.5 million in Q4 2025, and up 6.85% year-over-year from $87.2 million in Q1 2025.

Spyre Therapeutics (SYRE) Total Liabilities (2015 - 2026) Analysis & Trends

Spyre Therapeutics' Total Liabilities history runs 12 years deep, the most recent figure standing at $93.1 million for Q1 2026.

  • Quarterly Total Liabilities rose 6.85% year-over-year to $93.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $93.1 million (up 6.85% YoY) and the FY2025 annual result came in at $62.5 million, down 31.03% from the prior year.
  • Total Liabilities was $93.1 million for Q1 2026 at Spyre Therapeutics, up from $62.5 million in the prior quarter.
  • Across five years, Total Liabilities topped out at $253.6 million in Q2 2023 and bottomed at $18.8 million in Q1 2023.
  • A 5-year average of $70.8 million and a median of $65.6 million in 2023 frame the typical range for Total Liabilities.
  • Annual changes were most pronounced in 2023 — Total Liabilities jumped 1024.5% — and 2024, when it tumbled 75.68%.
  • Spyre Therapeutics' Total Liabilities stood at $20.8 million in 2022, then jumped by 251.69% to $73.3 million in 2023, then rose by 23.73% to $90.7 million in 2024, then plunged by 31.03% to $62.5 million in 2025, then surged by 48.92% to $93.1 million in 2026.
  • Business Quant data shows SYRE's Total Liabilities at $93.1 million in Q1 2026, $62.5 million in Q4 2025, and $49.5 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Total Liabilities (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - 60.46 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - 177.22 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 3.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - 7.33 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 7.12 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 9.45 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 15.48 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 1.62 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 753.82 Mn
10 Spyre Therapeutics 257.83 Mn 257.83 Mn - 93.14 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 93.14 Mn
Dec 31, 2025 62.55 Mn
Sep 30, 2025 49.50 Mn
Jun 30, 2025 83.06 Mn
Mar 31, 2025 87.17 Mn
Dec 31, 2024 90.68 Mn
Sep 30, 2024 93.70 Mn
Jun 30, 2024 61.68 Mn
Mar 31, 2024 81.93 Mn
Dec 31, 2023 73.29 Mn
Sep 30, 2023 65.56 Mn
Jun 30, 2023 253.58 Mn
Mar 31, 2023 18.80 Mn
Dec 31, 2022 20.84 Mn
Sep 30, 2022 24.01 Mn
Jun 30, 2022 22.55 Mn
Mar 31, 2022 21.51 Mn
Dec 31, 2021 25.99 Mn
Sep 30, 2021 26.98 Mn
Jun 30, 2021 27.96 Mn