Spyre Therapeutics (SYRE) Amortizatization of Intangibles (2015 - 2026)

Spyre Therapeutics posted quarterly Amortizatization of Intangibles of $2.1 million for Q1 2026, down 22.07% year-on-year from $2.6 million in Q1 2025, and up 134.29% on a QoQ basis from -$6.0 million in Q4 2025.

Spyre Therapeutics (SYRE) has 12 years of Amortizatization of Intangibles data on file, last reported at $2.1 million in Q1 2026.

  • For the quarter ending Q1 2026, Amortizatization of Intangibles fell 22.07% year-over-year to $2.1 million; the trailing twelve-month figure through Mar 2026 stood at -$583000.0 (down 105.02% YoY), and the FY2024 full-year result was $11.4 million, up 5083.64% from the prior year.
  • Amortizatization of Intangibles for Q1 2026 stood at $2.1 million, up from -$6.0 million in the prior quarter.
  • Across five years, Amortizatization of Intangibles topped out at $3.6 million in Q2 2024 and bottomed at -$6.0 million in Q4 2025.
  • The 5-year median for Amortizatization of Intangibles is $809500.0 (2022), against an average of $880000.0.
  • The widest annual swing landed in 2024, when Amortizatization of Intangibles surged 22156.25%; it then sank 348.24% in 2025.
  • A 5-year view of Amortizatization of Intangibles shows it stood at $105000.0 in 2022, then declined by 7.62% to $97000.0 in 2023, then surged by 2393.81% to $2.4 million in 2024, then tumbled by 348.24% to -$6.0 million in 2025, then surged by 134.29% to $2.1 million in 2026.
  • The last three Amortizatization of Intangibles figures came in at $2.1 million (Q1 2026), -$6.0 million (Q4 2025), and $1.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Amortizatization of Intangibles (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 13,267.00
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -
10 Spyre Therapeutics 5.55 Bn 5.55 Bn - 2.06 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 2.06 Mn
Mar 31, 2026 2.06 Mn
Dec 31, 2025 -6.01 Mn
Dec 31, 2025 -6.01 Mn
Sep 30, 2025 1.35 Mn
Sep 30, 2025 1.35 Mn
Jun 30, 2025 2.01 Mn
Jun 30, 2025 2.01 Mn
Mar 31, 2025 2.64 Mn
Mar 31, 2025 2.64 Mn
Dec 31, 2024 2.42 Mn
Dec 31, 2024 2.42 Mn
Sep 30, 2024 3.00 Mn
Sep 30, 2024 3.00 Mn
Jun 30, 2024 3.56 Mn
Jun 30, 2024 3.56 Mn
Mar 31, 2024 2.42 Mn
Mar 31, 2024 2.42 Mn
Sep 30, 2023 97,000.00
Sep 30, 2023 97,000.00
Jun 30, 2023 16,000.00
Jun 30, 2023 16,000.00
Mar 31, 2023 107,000.00
Mar 31, 2023 107,000.00
Dec 31, 2022 105,000.00
Dec 31, 2022 105,000.00
Sep 30, 2022 269,000.00
Sep 30, 2022 269,000.00
Jun 30, 2022 38,000.00
Jun 30, 2022 38,000.00
Mar 31, 2022 -15,000.00
Mar 31, 2022 -15,000.00
Dec 31, 2021 -58,000.00
Dec 31, 2021 -58,000.00
Sep 30, 2021 -149,000.00
Sep 30, 2021 -149,000.00
Jun 30, 2021 -160,000.00
Jun 30, 2021 -160,000.00
Mar 31, 2021 -181,000.00
Mar 31, 2021 -181,000.00
Dec 31, 2020 -120,000.00
Dec 31, 2020 -120,000.00
Sep 30, 2020 -11,000.00
Sep 30, 2020 -11,000.00
Jun 30, 2020 10,000.00
Jun 30, 2020 10,000.00
Mar 31, 2020 48,000.00
Mar 31, 2020 48,000.00
Dec 31, 2019 69,000.00
Dec 31, 2019 69,000.00
Sep 30, 2019 206,000.00
Sep 30, 2019 206,000.00
Jun 30, 2019 268,000.00
Jun 30, 2019 268,000.00
Mar 31, 2019 275,000.00
Mar 31, 2019 275,000.00
Dec 31, 2018 282,000.00
Dec 31, 2018 282,000.00
Sep 30, 2018 204,000.00
Sep 30, 2018 204,000.00
Jun 30, 2018 93,000.00
Jun 30, 2018 93,000.00
Mar 31, 2018 14,000.00
Mar 31, 2018 14,000.00
Dec 31, 2017 7,000.00
Dec 31, 2017 7,000.00
Sep 30, 2017 -2,000.00
Sep 30, 2017 -2,000.00
Jun 30, 2017 -129,000.00
Jun 30, 2017 -129,000.00
Mar 31, 2017 49,000.00
Mar 31, 2017 49,000.00
Dec 31, 2016 -152,000.00
Dec 31, 2016 -152,000.00
Sep 30, 2016 37,000.00
Sep 30, 2016 37,000.00
Jun 30, 2016 6,000.00
Jun 30, 2016 6,000.00
Mar 31, 2016 8,000.00
Mar 31, 2016 8,000.00
Dec 31, 2015 1,000.00
Dec 31, 2015 1,000.00