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Assets AverageDebt RatioDebt to EquityEnterprise ValueEquity AverageEquity RatioInvested CapitalReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested Capital

Spyre Therapeutics (SYRE) Return on Assets (2016 - 2025)

Spyre Therapeutics (SYRE) has disclosed Return on Assets for 10 consecutive years, with 0.24% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Return on Assets rose 16.0% year-over-year to 0.24%, compared with a TTM value of 0.24% through Dec 2025, up 16.0%, and an annual FY2025 reading of 0.22%, up 21.0% over the prior year.
  • Return on Assets was 0.24% for Q4 2025 at Spyre Therapeutics, up from 0.29% in the prior quarter.
  • Across five years, Return on Assets topped out at 0.24% in Q4 2025 and bottomed at 1.84% in Q2 2023.
  • Average Return on Assets over 5 years is 0.73%, with a median of 0.53% recorded in 2024.
  • The sharpest move saw Return on Assets tumbled -92bps in 2023, then skyrocketed 144bps in 2024.
  • Year by year, Return on Assets stood at 0.55% in 2021, then crashed by -87bps to 1.03% in 2022, then dropped by -20bps to 1.23% in 2023, then soared by 67bps to 0.4% in 2024, then soared by 40bps to 0.24% in 2025.
  • Business Quant data shows Return on Assets for SYRE at 0.24% in Q4 2025, 0.29% in Q3 2025, and 0.37% in Q2 2025.