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Assets AverageDebt RatioDebt to EquityEnterprise ValueEquity AverageEquity RatioInvested CapitalReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested Capital

Spyre Therapeutics (SYRE) Return on Assets (2016 - 2025)

Spyre Therapeutics' Return on Assets history spans 10 years, with the latest figure at 0.24% for Q4 2025.

  • For Q4 2025, Return on Assets rose 16.0% year-over-year to 0.24%; the TTM value through Dec 2025 reached 0.24%, up 16.0%, while the annual FY2025 figure was 0.22%, 21.0% up from the prior year.
  • Return on Assets reached 0.24% in Q4 2025 per SYRE's latest filing, up from 0.29% in the prior quarter.
  • In the past five years, Return on Assets ranged from a high of 0.24% in Q4 2025 to a low of 1.84% in Q2 2023.
  • Average Return on Assets over 5 years is 0.73%, with a median of 0.53% recorded in 2021.
  • Peak YoY movement for Return on Assets: tumbled -92bps in 2023, then skyrocketed 144bps in 2024.
  • A 5-year view of Return on Assets shows it stood at 0.55% in 2021, then crashed by -87bps to 1.03% in 2022, then dropped by -20bps to 1.23% in 2023, then soared by 67bps to 0.4% in 2024, then soared by 40bps to 0.24% in 2025.
  • Per Business Quant, the three most recent readings for SYRE's Return on Assets are 0.24% (Q4 2025), 0.29% (Q3 2025), and 0.37% (Q2 2025).