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Spyre Therapeutics (SYRE) Return on Assets: 2016-2025

Historic Return on Assets for Spyre Therapeutics (SYRE) over the last 10 years, with Sep 2025 value amounting to -0.29%.

  • Spyre Therapeutics' Return on Assets rose 22.00% to -0.29% in Q3 2025 from the same period last year, while for Sep 2025 it was -0.29%, marking a year-over-year increase of 22.00%. This contributed to the annual value of -0.44% for FY2024, which is 120.00% up from last year.
  • As of Q3 2025, Spyre Therapeutics' Return on Assets stood at -0.29%, which was up 23.47% from -0.37% recorded in Q2 2025.
  • In the past 5 years, Spyre Therapeutics' Return on Assets ranged from a high of -0.29% in Q3 2025 and a low of -1.84% during Q2 2023.
  • Moreover, its 3-year median value for Return on Assets was -0.50% (2024), whereas its average is -0.80%.
  • In the last 5 years, Spyre Therapeutics' Return on Assets crashed by 92bps in 2023 and then surged by 144bps in 2024.
  • Over the past 5 years, Spyre Therapeutics' Return on Assets (Quarterly) stood at -0.65% in 2021, then slumped by 38bps to -1.03% in 2022, then decreased by 20bps to -1.23% in 2023, then surged by 83bps to -0.40% in 2024, then rose by 22bps to -0.29% in 2025.
  • Its Return on Assets was -0.29% in Q3 2025, compared to -0.37% in Q2 2025 and -0.35% in Q1 2025.